Human Muscle Acetylcholine Receptor Alpha-subunit Gene (CHRNA1) Association with Autoimmune Myasthenia Gravis in Black, Mixed-Ancestry and Caucasian Subjects

Jeannine M. Heckmann; Karen E. Morrison; Barbara Emeryk-Szajewska; Halina Strugalska; JoAnn Bergoffen; Nicholas Willcox; John Newsom-Davis

doi:10.1006/jaut.1996.0021

Human Muscle Acetylcholine Receptor Alpha-subunit Gene (CHRNA1) Association with Autoimmune Myasthenia Gravis in Black, Mixed-Ancestry and Caucasian Subjects

Journal of Autoimmunity ◽

10.1006/jaut.1996.0021 ◽

1996 ◽

Vol 9 (2) ◽

pp. 175-180 ◽

Cited By ~ 20

Author(s):

Jeannine M. Heckmann ◽

Karen E. Morrison ◽

Barbara Emeryk-Szajewska ◽

Halina Strugalska ◽

JoAnn Bergoffen ◽

...

Keyword(s):

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Human Muscle ◽

Alpha Subunit ◽

Subunit Gene ◽

Mixed Ancestry ◽

Receptor Alpha ◽

Autoimmune Myasthenia

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Involvement of human muscle acetylcholine receptor alpha-subunit gene (CHRNA) in susceptibility to myasthenia gravis.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.91.11.4668 ◽

1994 ◽

Vol 91 (11) ◽

pp. 4668-4672 ◽

Cited By ~ 54

Author(s):

H. J. Garchon ◽

F. Djabiri ◽

J. P. Viard ◽

P. Gajdos ◽

J. F. Bach

Keyword(s):

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Human Muscle ◽

Alpha Subunit ◽

Subunit Gene ◽

Receptor Alpha

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Reconstitution of conformationally dependent epitopes on the N-terminal extracellular domain of the human muscle acetylcholine receptor alpha subunit expressed in Escherichia coli: implications for myasthenia gravis therapeutic approaches

International Immunology ◽

10.1093/intimm/12.9.1255 ◽

2000 ◽

Vol 12 (9) ◽

pp. 1255-1265 ◽

Cited By ~ 23

Author(s):

T. Tsouloufis

Keyword(s):

Escherichia Coli ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Extracellular Domain ◽

Human Muscle ◽

Alpha Subunit ◽

Therapeutic Approaches ◽

Receptor Alpha

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Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.

Journal of Clinical Investigation ◽

10.1172/jci114282 ◽

1989 ◽

Vol 84 (4) ◽

pp. 1174-1180 ◽

Cited By ~ 94

Author(s):

P L Schwimmbeck ◽

T Dyrberg ◽

D B Drachman ◽

M B Oldstone

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Molecular Mimicry ◽

Alpha Subunit ◽

Receptor Alpha ◽

Biologic Activity ◽

Simplex Virus

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Induction of acetylcholine receptor alpha-subunit gene expression in chicken myotubes by blocking electrical activity requires ongoing protein synthesis.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.87.4.1391 ◽

1990 ◽

Vol 87 (4) ◽

pp. 1391-1395 ◽

Cited By ~ 17

Author(s):

A. Duclert ◽

J. Piette ◽

J. P. Changeux

Keyword(s):

Gene Expression ◽

Protein Synthesis ◽

Electrical Activity ◽

Acetylcholine Receptor ◽

Alpha Subunit ◽

Subunit Gene ◽

Receptor Alpha

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Experimental study Improved methodology to obtain large quantities of correctly folded recombinant N-terminal extracellular domain of the human muscle acetylcholine receptor for inducing experimental autoimmune myasthenia gravis in rats

Archives of Medical Science ◽

10.5114/aoms.2013.36921 ◽

2014 ◽

Vol 2 ◽

pp. 389-395 ◽

Cited By ~ 1

Author(s):

Chenjing Sun ◽

Hongliang Zhang ◽

Jiang Xu ◽

Jie Gao ◽

Xiaokun Qi ◽

...

Keyword(s):

Experimental Study ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Extracellular Domain ◽

Human Muscle ◽

Experimental Autoimmune Myasthenia Gravis ◽

Autoimmune Myasthenia ◽

Experimental Autoimmune

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Acetylcholine Receptor Alpha Subunit mRNA Expression in Human Thymus: Augmented Expression in Myasthenia Gravis and Upregulation by Interferon-γ

Clinical Immunology ◽

10.1006/clim.1999.4689 ◽

1999 ◽

Vol 91 (2) ◽

pp. 170-177 ◽

Cited By ~ 20

Author(s):

Yi Zheng ◽

Lisa M. Wheatley ◽

Thomas Liu ◽

Arnold I. Levinson

Keyword(s):

Myasthenia Gravis ◽

Mrna Expression ◽

Acetylcholine Receptor ◽

Interferon Γ ◽

Alpha Subunit ◽

Receptor Alpha ◽

Subunit Mrna ◽

Human Thymus

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T-Cell Epitopes on the Human Acetylcholine Receptor alpha-Subunit Residues 10-84 in Myasthenia Gravis

Scandinavian Journal of Immunology ◽

10.1111/j.1365-3083.1992.tb02958.x ◽

1992 ◽

Vol 36 (3) ◽

pp. 435-442 ◽

Cited By ~ 6

Author(s):

R. AHLBERG ◽

Q. YI ◽

H. ENG ◽

R. PIRSKANEN ◽

A. K. LEFVERT

Keyword(s):

T Cell ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Alpha Subunit ◽

T Cell Epitopes ◽

Receptor Alpha

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Stimulation of Autoimmune Helper T Lymphocytes from Patients with Myasthenia Gravis with Synthetic Peptides of the Acetylcholine Receptor Alpha Subunit

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1988.tb27154.x ◽

1988 ◽

Vol 540 (1 Advances in N) ◽

pp. 511-512 ◽

Cited By ~ 1

Author(s):

REINHARD HOHLFELD ◽

KLAUS V. TOYKA ◽

LUCINDA L. MINER ◽

BIANCA M. CONTI-TRONCONI

Keyword(s):

T Lymphocytes ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Synthetic Peptides ◽

Alpha Subunit ◽

Receptor Alpha ◽

Helper T Lymphocytes ◽

Stimulation Of

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Stimulation of autoimmune helper T-lymphocytes from myasthenia gravis patients with synthetic peptides of the acetylcholine receptor alpha subunit

Journal of Neuroimmunology ◽

10.1016/0165-5728(87)90248-7 ◽

1987 ◽

Vol 16 (1) ◽

pp. 79

Author(s):

Reinhard Hohlfeld ◽

Klaus V. Toyka ◽

Bianca M. Conti-Tronconi

Keyword(s):

T Lymphocytes ◽

Myasthenia Gravis ◽

Acetylcholine Receptor ◽

Synthetic Peptides ◽

Alpha Subunit ◽

Receptor Alpha ◽

Helper T Lymphocytes ◽

Stimulation Of

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A developmental and tissue-specific enhancer in the mouse skeletal muscle acetylcholine receptor alpha-subunit gene regulated by myogenic factors.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54612-3 ◽

1991 ◽

Vol 266 (33) ◽

pp. 22588-22596

Author(s):

C.A. Prody ◽

J.P. Merlie

Keyword(s):

Skeletal Muscle ◽

Acetylcholine Receptor ◽

Alpha Subunit ◽

Subunit Gene ◽

Tissue Specific ◽

Receptor Alpha ◽

Mouse Skeletal Muscle ◽

Myogenic Factors

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