Role of the Histamine H3 Receptor in the Central Nervous System

2016 ◽  
pp. 277-299 ◽  
Author(s):  
Eberhard Schlicker ◽  
Markus Kathmann
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Histamine H3 Receptor ◽  
H3 Receptor ◽  
The Central Nervous System ◽  
Histamine H3

4-Alkynylphenyl Imidazolylpropyl Ethers as Selective Histamine H3-Receptor Antagonists with High Oral Central Nervous System Activity

1998 ◽  
Vol 41 (21) ◽  
pp. 4171-4176 ◽  
Author(s):  
Michael Krause ◽  
Xavier Ligneau ◽  
Holger Stark ◽  
Monique Garbarg ◽  
Jean-Charles Schwartz ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Receptor Antagonists ◽  
Histamine H3 Receptor ◽  
System Activity ◽  
Nervous System Activity ◽  
H3 Receptor ◽  
Central Nervous System Activity ◽  
Histamine H3

scholarly journals 4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity

2019 ◽  
Vol 62 (23) ◽  
pp. 10848-10866 ◽  
Author(s):  
Gábor Wágner ◽  
Tamara A. M. Mocking ◽  
Marta Arimont ◽  
Gustavo Provensi ◽  
Barbara Rani ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Histamine H3 Receptor ◽  
System Activity ◽  
High Affinity ◽  
Nervous System Activity ◽  
H3 Receptor ◽  
Central Nervous System Activity ◽  
Histamine H3

Role of a nurse in the rehabilitation of children using ReviMotion hardware and software complex

2020 ◽  
pp. 49-56
Author(s):  
T. Shirshova
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
School Age Children ◽  
Equipment Management ◽  
School Age ◽  
Rehabilitation Process ◽  
Software Complex ◽  
Trained Personnel ◽  
The Central Nervous System

Disorders of the musculoskeletal system in school-age children occupy 1-2 places in the structure of functional abnormalities. Cognitive impairment without organic damage to the central nervous system is detected in 30-56% of healthy school children. Along with the increase in the incidence rate, the demand for rehabilitation systems, which allow patients to return to normal life as soon as possible and maintain the motivation for the rehabilitation process, is also growing. Adaptation of rehabilitation techniques, ease of equipment management, availability of specially trained personnel and availability of technical support for complexes becomes important.

The Role of Neuropeptide Y and Peptide YY in the Development of Obesity via Gut-brain Axis

2019 ◽  
Vol 20 (7) ◽  
pp. 750-758 ◽  
Author(s):  
Yi Wu ◽  
Hengxun He ◽  
Zhibin Cheng ◽  
Yueyu Bai ◽  
Xi Ma
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuropeptide Y ◽  
Metabolic Diseases ◽  
Peptide Yy ◽  
Vital Role ◽  
Gut Peptides ◽  
Nonalcoholic Fatty Liver ◽  
The Central Nervous System

Obesity is one of the main challenges of public health in the 21st century. Obesity can induce a series of chronic metabolic diseases, such as diabetes, dyslipidemia, hypertension and nonalcoholic fatty liver, which seriously affect human health. Gut-brain axis, the two-direction pathway formed between enteric nervous system and central nervous system, plays a vital role in the occurrence and development of obesity. Gastrointestinal signals are projected through the gut-brain axis to nervous system, and respond to various gastrointestinal stimulation. The central nervous system regulates visceral activity through the gut-brain axis. Brain-gut peptides have important regulatory roles in the gut-brain axis. The brain-gut peptides of the gastrointestinal system and the nervous system regulate the gastrointestinal movement, feeling, secretion, absorption and other complex functions through endocrine, neurosecretion and paracrine to secrete peptides. Both neuropeptide Y and peptide YY belong to the pancreatic polypeptide family and are important brain-gut peptides. Neuropeptide Y and peptide YY have functions that are closely related to appetite regulation and obesity formation. This review describes the role of the gutbrain axis in regulating appetite and maintaining energy balance, and the functions of brain-gut peptides neuropeptide Y and peptide YY in obesity. The relationship between NPY and PYY and the interaction between the NPY-PYY signaling with the gut microbiota are also described in this review.

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