Cystic and Mucinous Lesions: Mucocele and Low-Grade Mucoepidermoid Carcinoma

2008 ◽  
pp. 159-181
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Low Grade

Hosszú túléléssel járó malignus tumor miatti tüdőmegtartó centrális főhörgőplasztikáink

2013 ◽  
Vol 66 (6) ◽  
pp. 338-347
Author(s):  
László István Kecskés ◽  
Győző Bátor ◽  
Árpád Füredi ◽  
Pál Gehér ◽  
Béla Kiss ◽  
...  
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Low Grade ◽  
Karnofsky Index

AbsztraktBevezetés:A daganatos haláloki statisztikát vezető malignus hörgőtumorok eseteiben hosszú túlélésre csak a radikálisan operált betegek számíthatnak. Mégis, jól lokalizált, centrális és low grade malignomák kezelésében a tüdőmegtartó centrális bronchusplasztikáknak is helye lehet.Célkitűzés:A parenchymakonzerváló műtétek az egyik oldali teljes tüdő eltávolításának vagy az inoperabilitásnak a pozitív alternatívái lehetnek. Értékét a mortalitás, a szövődmények és a túlélés alapján lehet megítélni.Beteganyag és módszer:1985–2012 között 7130 hörgőcarcinomás beteget operáltunk. 80 centrális bronchoplasztikai műtétből7 esetben a jobb vagy bal főhörgő izolált vagy az egész bifurcatiós carina resectiója és a tüdő autotranszplantációja révén teljes tüdőmegtartást értünk el.A 4 nő és 3 férfi átlagéletkora 28,5 (14–58) év volt. 4 beteg carcinoid, 1 laphámrák, 1 mucoepidermoid carcinoma miatt, 1 beteg kissejtes tüdőrák (SCLC) miatti kemo-radioterápia (KRT) után került műtétre. 1 esetben izolált carina-, 1 betegnél balfőhörgő-, 5 betegnél jobbfőhörgő-resectio történt. Az anastomosist csomós PDS öltésekkel a műtéti területen át bevezetett steril tubus (6 beteg), illetve jet-katéter (1 beteg) felett varrtuk. A betegeket műtét után extubáltuk.Eredmények:Műtéti mortalitás nem volt. A korai posztoperatív szakban ismételt bronchoscopos leszívásokat alkalmaztunk. A SCLC miatt operált betegnél subacut anastomosisstenosis miatt kétoldali ideiglenes stentimplantációt alkalmaztunk. 174 hónapja él, Karnofsky-index 90%. 5 másik beteg is tumorrecidíva, metastasis nélkül él. A laphámrák miatti izolált jobbfőhörgő-resecált beteg 83 hónap után bal oldali disseminált kissejtes tüdőrák miatt exitált.Átlagos túlélés: 118 hónap (7–233).Következtetések:Fiatal betegeknél, lokalizált centrális főhörgő rosszindulatú daganatok szelektált eseteiben, izolált carina-főhörgő resectióval nemcsak teljes tüdőmegtartás, hanem hosszú túlélés is elérhető. Az irodalomban vannak hasonlóan sikeres, kisebb szériák és esetbemutatások (összes esetszám 200 alatt), de hosszú távú eredményekről kevés az adat. Hazánkban ez a legnagyobb széria, eredményeink nemzetközi kitekintéssel mérve is helytállóak.

Different effects of bronchoscopic interventions on children and adults with tracheobronchial mucoepidermoid carcinoma

2021 ◽  
pp. 030089162199589
Author(s):  
Zhang Jieli ◽  
Zhou Yunzhi ◽  
Zhang Nan ◽  
Zou Heng ◽  
Wang Hongwu ◽  
...  
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Argon Plasma Coagulation ◽  
Survival Rates ◽  
Argon Plasma ◽  
Rigid Bronchoscopy ◽  
Low Grade ◽  
High Grade ◽  
Adult Group ◽  
Histologic Grading ◽  
Comprehensive Therapy

Aims: To investigate the efficacy and safety of minimally invasive bronchoscopic interventions for patients with tracheobronchial mucoepidermoid carcinoma (MEC). Methods: Patients with tracheobronchial MEC were included in this retrospective study, and the clinical features, histologic grading, treatments, and cumulative survival rates were calculated. Patients were categorized into child (n = 16) and adult (n = 19) group according to their ages. Histologic grading, treatments, and survival status were compared between the two groups. Results: In pathology, high-grade MEC counts for 6.77% and 42.10% in the child and adult group, respectively. As tumor growth pattern was concerned, 93.33% and 21.05% tumors in the child and adult group present intratracheal type. Multiple bronchoscopic interventions were conducted, including rigid bronchoscopy, argon plasma coagulation (APC), dioxide carbon cryotherapy, and electric loop. Tumors could be removed by multiple bronchoscopic interventions. Bronchoscopy-associated complications were rare, including an oral mucosa injury and a glottis edema. In the child group, one patient underwent left upper lung lobectomy. In the adult group, lobectomy and/or chemotherapy and/or radiotherapy were conducted in seven patients. The 5-year survival rate was 100% and 68.90% in the child and the adult group, respectively. Conclusions: Almost all children have low-grade and intratracheal MEC; 2/5 adults have invasive high-grade MEC. Multiple bronchoscopic interventions are effective in erasing low-grade intratracheal MEC without severe complications. For high-grade invasive MEC, aggressive and comprehensive therapy should be considered.

Salivary Gland Mucoepidermoid Carcinoma, Low Grade: Diagnostic Pearls Among Pitfalls

2018 ◽  
Vol 7 (5) ◽  
pp. S18
Author(s):  
Ameer Hamza ◽  
Ahmed Alrajjal ◽  
Zhifei Zhang ◽  
Basim Al-Khafaji
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Low Grade

LOW-GRADE MUCOEPIDERMOID CARCINOMA OF LOWER LIP MIMICKING MUCOCELE

2020 ◽  
Vol 130 (3) ◽  
pp. e202
Author(s):  
RICARDO NATã FONSECA SILVA ◽  
SEBASTIãO SILVéRIO DE SOUSA-NETO ◽  
JéSSICA SILVA BUSO ◽  
ROBSON RODRIGUES GARCIA ◽  
ENEIDA FRANCO VÊNCIO ◽  
...  
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Low Grade ◽  
Lower Lip

scholarly journals Primary intraosseous mucoepidermoid carcinoma of the mandible: radiographic evolution and clinicopathological features

2019 ◽  
Vol 12 (4) ◽  
pp. e224612
Author(s):  
Nicholas B Abt ◽  
Matthew E Lawler ◽  
Joseph Zacharias ◽  
Edward T Lahey
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Malignant Neoplasm ◽  
Inflammatory Lesion ◽  
Advancement Flap ◽  
Careful Examination ◽  
Iliac Crest Bone Graft ◽  
Odontogenic Cysts ◽  
Low Grade ◽  
Malignant Tumours ◽  
Second Molar

Mucoepidermoid carcinoma (MEC) can be rarely found as a primarily intraosseous lesion and mistaken for other intraosseous or odontogenic pathology. A 65-year-old man had a poorly defined radiolucency distal to the left mandibular second molar root. Periapical radiographs demonstrated a minor radiolucency from 2.5 years prior. An oral and maxillofacial surgeon felt the radiolucency represented periodontal disease, extracting tooth #18. The differential diagnosis of mixed radiolucent/radio-opaque mandibular lesions includes: (1) fibro-osseous lesion, (2) odontogenic and non-odontogenic cyst, (3) infection and inflammatory lesion, or (4) benign or malignant neoplasm (odontogenic, non-odontogenic, or metastatic). Histological analysis revealed low-grade MEC. A composite resection was performed with a 1 cm margin from first molar to ascending ramus. A buccal fat pad advancement flap covered the defect with an iliac crest bone graft placed later for a resulting osseous defect. Careful examination and diagnostic work-up for odontogenic cysts should be provided as they may harbour malignant tumours.

scholarly journals Postoperative Radiation Therapy for Parotid Mucoepidermoid Carcinoma

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Meghan P. Olsen ◽  
Allen O. Mitchell ◽  
Edward F. Miles
Keyword(s):  
Radiation Therapy ◽  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Controlled Trials ◽  
Adjuvant Radiation ◽  
Low Grade ◽  
Postoperative Radiation ◽  
Postoperative Radiation Therapy ◽  
Randomized Controlled

Salivary gland cancers are rare and represent approximately 5% of all head and neck cancers and only 0.3% of all malignancies. The majority (75%) of salivary gland tumors occur in the parotid gland, and while benign lesions are more common, mucoepidermoid carcinoma (MEC) makes up 40–50% of malignant parotid gland tumors. No randomized controlled trials exist regarding the role of adjuvant radiation for patients who undergo surgical resection of low-grade MECs. Herein, we report two cases of successful postoperative radiation therapy in low-grade, pT2N0 MEC of the parotid gland. The role of adjuvant radiation therapy for patients with MEC of the parotid gland is based on data from institution reviews and lacks data from randomized controlled trials. Per our review of the literature, the pathological findings of positive surgical margins and/or perineural invasion in two patients with low-grade MEC of the parotid gland warranted adjuvant radiation for improved local control after partial parotidectomy. Both patients tolerated postoperative radiation therapy with only mild side effects and, at last follow-up, five years after completion of therapy, had no clinical or radiographic evidence of either local recurrence or distant metastasis.

scholarly journals Oncocytes in Mucoepidermoid Carcinoma of the Palate: Diagnostic Challenges

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Rammohan Kumar ◽  
Srikant Natarajan ◽  
K.S. Sneha ◽  
Nunna Sai Chitra ◽  
Karen Boaz ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Salivary Glands ◽  
Mucoepidermoid Carcinoma ◽  
Good Prognosis ◽  
Salivary Gland Tumour ◽  
Diagnostic Workup ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Gland Tumour

The origin of a salivary gland tumour is attributed to cells at various levels of differentiation which present histologically as diverse tissues and cellular patterns. Mitochondria-rich, eosinophilic oncocytes are cells commonly encountered in salivary gland neoplasms. We report a case of mucoepidermoid carcinoma (MEC) in the palate of a 43-year-old female that exhibited a prominent oncocytic component. While the parotid and submandibular glands have been reported as predominant sites for oncocytic MEC (OMEC), the palate and minor salivary glands are rare sites for occurrence. Also, most of the reported cases of OMEC have been histologically of low-grade mucoepidermoid carcinoma with large cystic spaces and good prognosis. In this article, we discuss the differential diagnosis and diagnostic workup of an MEC presenting with oncocytes.

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