Are there two Types of Adenosine Receptors in Peripheral Tissues?

Purines ◽  
1985 ◽  
pp. 75-84 ◽  
Author(s):  
Michael G. Collis
Keyword(s):  
Adenosine Receptors ◽  
Peripheral Tissues

Autoradiographic visualization of A1-adenosine receptors in brain and peripheral tissues of rat and guinea pig using 125I-HPIA

1988 ◽  
Vol 87 (3) ◽  
pp. 215-220 ◽  
Author(s):  
Ruthild G. Weber ◽  
C.Richard Jones ◽  
JoséM. Palacios ◽  
Martin J. Lohse
Keyword(s):  
Guinea Pig ◽  
Adenosine Receptors ◽  
Peripheral Tissues ◽  
A1 Adenosine Receptors

Melatonin: a novel strategy for prevention of obesity and fat accumulation in peripheral organs through the improvements of circadian rhythms and antioxidative capacity

2020 ◽  
Vol 3 (1) ◽  
pp. 58-76 ◽  
Author(s):  
Bohan Rong ◽  
Qiong Wu ◽  
Chao Sun
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Circadian Rhythms ◽  
Regulatory Mechanisms ◽  
Antioxidative Capacity ◽  
Unicellular Alga ◽  
Peripheral Tissues ◽  
Peripheral Organs ◽  
Regulatory Effects ◽  
Novel Strategy

Melatonin is a well-known molecule for its involvement in circadian rhythm regulation and its contribution to protection against oxidative stress in organisms including unicellular alga, animals and plants. Currently, the bio-regulatory effects of melatonin on the physiology of various peripheral tissues have drawn a great attention of scientists. Although melatonin was previously defined as a neurohormone secreted from pineal gland, recently it has been identified that virtually, every cell has the capacity to synthesize melatonin and the locally generated melatonin has multiple pathophysiological functions, including regulations of obesity and metabolic syndromes. Herein, we focus on the effects of melatonin on fat deposition in various peripheral organs/tissues. The two important regulatory mechanisms related to the topic, i.e., the improvements of circadian rhythms and antioxidative capacity will be thoroughly discussed since they are linked to several biomarkers involved in obesity and energy imbalance, including metabolism and immunity. Furthermore, several other functions of melatonin which may serve to prevent or promote obesity and energy dysmetabolism-induced pathological states are also addressed. The organs of special interest include liver, pancreas, skeletal muscle, adipose tissue and the gut microbiota.

280-LB: Role of A1 and A3 Adenosine Receptors in Whole Body Glucose Metabolism

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 280-LB ◽  
Author(s):  
SHANU JAIN ◽  
DILIP K. TOSH ◽  
MARC REITMAN ◽  
KENNETH A. JACOBSON
Keyword(s):  
Glucose Metabolism ◽  
Adenosine Receptors ◽  
Whole Body

Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues

Diabetes ◽  
1992 ◽  
Vol 41 (2) ◽  
pp. 241-253 ◽  
Author(s):  
Y. J. Yang ◽  
I. Hope ◽  
M. Ader ◽  
R. A. Poulin ◽  
R. N. Bergman
Keyword(s):  
Insulin Sensitivity ◽  
Glucose Uptake ◽  
Dose Response ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Peripheral Tissues
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