Experimental Therapies for Multiple Sclerosis: Historical Perspective

1992 ◽  
pp. 1-15 ◽  
Author(s):  
George W. Ellison
Keyword(s):  
Multiple Sclerosis ◽  
Historical Perspective ◽  
Experimental Therapies

Imaging and depression in multiple sclerosis: a historical perspective

2021 ◽  
Author(s):  
Fabio Giuseppe Masuccio ◽  
Giulia Gamberini ◽  
Massimiliano Calabrese ◽  
Claudio Solaro
Keyword(s):  
Multiple Sclerosis ◽  
Historical Perspective

The Epidemiology of Multiple Sclerosis: An Historical Perspective

2017 ◽  
Author(s):  
Kassandra L. Munger
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Environmental Factors ◽  
Sex Ratio ◽  
Cigarette Smoking ◽  
Historical Perspective ◽  
Current Evidence ◽  
Descriptive Epidemiology ◽  
Ebv Infection ◽  
Over Time

The descriptive epidemiology has proved to be dynamic with attenuation of the latitude gradient, increase in incidence among women, and changes in the sex ratio over time, indicating that recent changes in environmental factors are responsible. Although we still do not know the causes of MS, or how to prevent it, the current evidence supports causal roles for EBV infection, vitamin D, and cigarette smoking.

scholarly journals Russell W Brain and the aetiology of multiple sclerosis--a historical perspective

QJM ◽  
2014 ◽  
Vol 107 (6) ◽  
pp. 423-427 ◽  
Author(s):  
J. Pakpoor ◽  
S. V. Ramagopalan
Keyword(s):  
Multiple Sclerosis ◽  
Historical Perspective

Experimental therapies for multiple sclerosis: current status

1992 ◽  
Vol 59 (1) ◽  
pp. 63-74 ◽  
Author(s):  
D. E. Goodkin ◽  
R. M. Ransohoff ◽  
R. A. Rudick
Keyword(s):  
Multiple Sclerosis ◽  
Current Status ◽  
Experimental Therapies

Multiple Sclerosis

2019 ◽  
pp. 59-100
Author(s):  
Gary Birnbaum
Keyword(s):  
Multiple Sclerosis ◽  
Monoclonal Antibodies ◽  
Stem Cell ◽  
Plasma Exchange ◽  
Practical Approach ◽  
Oral Disease ◽  
Adult Onset ◽  
Experimental Therapies ◽  
Disease Modifying ◽  
Underlying Pathology

This chapter provides a broad overview of adult onset multiple sclerosis (MS), with the intent of providing a practical approach to diagnosis and treatments. It starts by looking at the epidemiology and demographics of MS, followed by a detailed discussion of the pathogenesis and pathology of MS. The chapter discusses the diagnosis, the various stages, and the symptoms of MS. Treatment of the disease, addressing both underlying pathology and symptoms, are discussed in detail. These include discussions of established therapies such as injectable and oral disease-modifying therapies, monoclonal antibodies, plasmapheresis or plasma exchange (PLEX), as well as new, and currently experimental therapies such as autologous stem cell transplants. Emphasis is especially directed at the often-underutilized management of MS-related symptoms.

scholarly journals Multiple sclerosis: treatment approaches in a historical perspective (clinical lecture, continued)

2016 ◽  
pp. 4-10
Author(s):  
G. Chupryna ◽  
N. Svyrydova ◽  
Y. Trufanov ◽  
N. Khanenko ◽  
T. Cherednichenko ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Historical Perspective ◽  
Treatment Approach ◽  
Parallel Flow ◽  
Human Organism ◽  
Diagnostic Features ◽  
Common Features ◽  
Appropriate Treatment ◽  
Syndromic Diagnosis ◽  
Multiple Sclerosis Treatment

Analytical view of the human organism, its physiology and pathology, treatment methods, formed under the influence of many centuries of observing the progress of the disease, when there was not this or that individual symptoms and groups related by birth, with common features and parallel flow of symptoms, under the influence of treatment and its effects have been studied as weight, texture, color, damaged organs, the link between a specific and complex pathology of affected organs and tissues. Thus was formed syndromal diagnosis of multiple sclerosis, where each syndrome reflects the general, substantiality and local disturbances, had characteristic diagnostic features. On the basis of this multi-faceted study of the patient was placed syndromic diagnosis and the appropriate treatment approach, aimed at restoring the overall balance of the body's defenses.

scholarly journals Can we Depend on Sunshine for Vitamin D? A mini review and historical perspective

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kirti Mohan Marya
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Vitamin D ◽  
Middle East ◽  
Vitamin D Deficiency ◽  
Metabolic Disorders ◽  
Historical Perspective ◽  
Sunlight Exposure

Worldwide studies have confirmed that vast population globally is suffering from vitamin D deficiency that can be linked to not only calcium and bone metabolic disorders, but also to diabetes, hypertension, rheumatoid arthritis and multiple sclerosis. Traditionally, inadequate sunlight exposure was implicated in Vitamin D deficiency. However recent studies from the Middle East and other countries suggest the contrary and thus unreliable. Test based diagnostics remain the most desirable way to prevent and treat Vitamin D deficiency rather than relying on sunshine.

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