Selection of Growth Factors and Myelomas To Enhance Monoclonal Antibody-Producing Hybridoma Formation

1987 ◽  
pp. 195-208
Author(s):  
Janet H. Ransom ◽  
Martin V. Haspel
Keyword(s):  
Monoclonal Antibody ◽  
Growth Factors ◽  
Selection Of

Selection of aptamers with high affinity and high specificity against C595, an anti-MUC1 IgG3 monoclonal antibody, for antibody targeting

2005 ◽  
Vol 296 (1-2) ◽  
pp. 45-62 ◽  
Author(s):  
Sotiris Missailidis ◽  
Despina Thomaidou ◽  
K. Eszter Borbas ◽  
Mike R. Price
Keyword(s):  
Monoclonal Antibody ◽  
High Specificity ◽  
High Affinity ◽  
Antibody Targeting ◽  
Selection Of

Mapping the conformational epitope of a therapeutic monoclonal antibody against HBsAg by in vivo selection of HBV escape variants

Hepatology ◽  
2021 ◽  
Author(s):  
Chang‐Ru Wu ◽  
Hyun‐Jin Kim ◽  
Cheng‐Pu Sun ◽  
Chen‐Yen Chung ◽  
You‐Yu Lin ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Conformational Epitope ◽  
Therapeutic Monoclonal Antibody ◽  
In Vivo Selection ◽  
Selection Of

scholarly journals Mammalian cell surface display for monoclonal antibody-based FACS selection of viral envelope proteins

mAbs ◽  
2017 ◽  
Vol 9 (7) ◽  
pp. 1052-1064 ◽  
Author(s):  
Tim-Henrik Bruun ◽  
Veronika Grassmann ◽  
Benjamin Zimmer ◽  
Benedikt Asbach ◽  
David Peterhoff ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Cell Surface ◽  
Mammalian Cell ◽  
Surface Display ◽  
Cell Surface Display ◽  
Envelope Proteins ◽  
Viral Envelope ◽  
Selection Of ◽  
Viral Envelope Proteins

Generation and Characterization of a Murine Monoclonal Antibody Specific for the Human T1-Cd5 Molecule

1987 ◽  
Vol 2 (3) ◽  
pp. 143-150 ◽  
Author(s):  
Federico Genzano ◽  
Ada Funaro ◽  
Massimo Alessio ◽  
Lucia B. De Monte ◽  
Graziella Bellone ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
T Cell ◽  
T Lymphocytes ◽  
Membrane Glycoprotein ◽  
Functional Features ◽  
Specific Membrane ◽  
Murine Monoclonal Antibodies ◽  
Selection Of

Murine monoclonal antibodies (MoAbs) have found widespread applications in the characterization of the molecular and functional features of lymphocyte differentiation antigens. The present paper summarizes the results of our work dealing with the production and selection of a murine MoAb recognizing a molecule expressed during the whole differentiative life of T lymphocytes. The MoAb CB01 resulted to be specific for an apparently unique epitope of the T-cell specific membrane glycoprotein T1-CD5.

Selection of a monoclonal antibody to detect PVYN and its use in ELISA and DIBA assays

1993 ◽  
Vol 15 (4) ◽  
pp. 293-300 ◽  
Author(s):  
R.P. Singh ◽  
A. Boucher ◽  
T.H. Somerville ◽  
A.K. Dhar
Keyword(s):  
Monoclonal Antibody ◽  
Selection Of

Selection of a dtpa chelate conjugate for monoclonal antibody targeting to a human colonic tumor in nude mice

1990 ◽  
Vol 46 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Robert M. Sharkey ◽  
Cecilia Motta-Hennessy ◽  
Otto A. Gansow ◽  
Martin W. Brechbiel ◽  
Irwin Fand ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Nude Mice ◽  
Colonic Tumor ◽  
Antibody Targeting ◽  
Selection Of

Vanadium and bone development: putative signaling pathwaysThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.

2006 ◽  
Vol 84 (7) ◽  
pp. 677-686 ◽  
Author(s):  
D.A. Barrio ◽  
S.B. Etcheverry
Keyword(s):  
Growth Factors ◽  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Bone Development ◽  
Second Messengers ◽  
Vanadium Compounds ◽  
Intracellular Signaling Pathways ◽  
Osteoblast Cell Line ◽  
Secondary Side ◽  
Selection Of

Vanadium is a trace element present in practically all cells in plants and animals. It exerts interesting actions in living systems. At pharmacological doses, vanadium compounds display relevant biological actions such as mimicking insulin and growth factors as well as having osteogenic activity. Some vanadium compounds also show antitumoral properties. The importance of vanadium in bone arises from the studies developed to establish the essentiality of this element in animals and humans. Bone tissue, where the element seems to play an important role, accumulates great amounts of vanadium. This paper reviews the physiology of osteoblasts, the involvement of different growth factors on bone development, and the effects of vanadium derivatives on the skeletal system of animal models and bone-related cells. Two cellular lines are discussed in particular; one derived from a rat osteosarcoma (UMR106) and the other is a nontransformed osteoblast cell line (MC3T3-E1). The effects of different growth factors and their mechanisms of action in these cellular lines are reviewed. These models of osteoblasts are especially useful in understanding the intracellular signaling pathways of vanadium derivatives in hard tissues. Vanadium uses an intricate interplay of intracellular mechanisms to exert different biochemical and pharmacological actions. The effects of vanadium derivatives on some cellular signaling pathways related to insulin are compiled in this review. The comprehension of these intracellular signaling pathways may facilitate the design of vanadium compounds with promising therapeutic applications as well as the understanding of secondary side effects derived from the use of vanadium as a therapeutic agent.

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