Da Qing, Finnish DPP, Tripod, and Dream: Lifestyle and Thiazolidinediones in the Prevention of Diabetes

2012 ◽  
pp. 189-202
Author(s):  
Mariela Glandt ◽  
Zachary Bloomgarden
Diabetes ◽  
1989 ◽  
Vol 38 (12) ◽  
pp. 1647-1651 ◽  
Author(s):  
E. P. Reich ◽  
D. Scaringe ◽  
J. Yagi ◽  
R. S. Sherwin ◽  
C. A. Janeway

Diabetes ◽  
1989 ◽  
Vol 38 (1) ◽  
pp. 24-30 ◽  
Author(s):  
D. Burstein ◽  
J. P. Mordes ◽  
D. L. Greiner ◽  
D. Stein ◽  
N. Nakamura ◽  
...  

2020 ◽  
Vol 16 (7) ◽  
pp. 674-689 ◽  
Author(s):  
Ronald B. Brown

This article presents a scoping review and synthesis of research findings investigating the toxic cellular accumulation of dysregulated inorganic phosphate—phosphate toxicity—as a pathophysiological determinant of diabetes and diabetic complications. Phosphorus, an essential micronutrient, is closely linked to the cellular metabolism of glucose for energy production, and serum inorganic phosphate is often transported into cells along with glucose during insulin therapy. Mitochondrial dysfunction and apoptosis, endoplasmic reticulum stress, neuronal degeneration, and pancreatic cancer are associated with dysregulated levels of phosphate in diabetes. Ectopic calcification involving deposition of calcium-phosphate crystals is prevalent throughout diabetic complications, including vascular calcification, nephropathy, retinopathy, and bone disorders. A low-glycemic, low-phosphate dietary intervention is proposed for further investigations in the treatment and prevention of diabetes and related diabetic pathologies.


Life Sciences ◽  
1993 ◽  
Vol 53 (26) ◽  
pp. PL453-PL458 ◽  
Author(s):  
Irving Lieberman ◽  
Brian V. Heil ◽  
W.Kim Seow ◽  
Y.H. Thong

Diabetologia ◽  
2020 ◽  
Author(s):  
Shammi Luhar ◽  
Dimple Kondal ◽  
Rebecca Jones ◽  
Ranjit M. Anjana ◽  
Shivani A. Patel ◽  
...  

Abstract Aims/hypothesis We aimed to estimate the lifetime risk of diabetes and diabetes-free life expectancy in metropolitan cities in India among the population aged 20 years or more, and their variation by sex, age and BMI. Methods A Markov simulation model was adopted to estimate age-, sex- and BMI-specific lifetime risk of developing diabetes and diabetes-free life expectancy. The main data inputs used were as follows: age-, sex- and BMI-specific incidence rates of diabetes in urban India taken from the Centre for Cardiometabolic Risk Reduction in South Asia (2010–2018); age-, sex- and urban-specific rates of mortality from period lifetables reported by the Government of India (2014); and prevalence of diabetes from the Indian Council for Medical Research INdia DIABetes study (2008–2015). Results Lifetime risk (95% CI) of diabetes in 20-year-old men and women was 55.5 (51.6, 59.7)% and 64.6 (60.0, 69.5)%, respectively. Women generally had a higher lifetime risk across the lifespan. Remaining lifetime risk (95% CI) declined with age to 37.7 (30.1, 46.7)% at age 60 years among women and 27.5 (23.1, 32.4)% in men. Lifetime risk (95% CI) was highest among obese Indians: 86.0 (76.6, 91.5)% among 20-year-old women and 86.9 (75.4, 93.8)% among men. We identified considerably higher diabetes-free life expectancy at lower levels of BMI. Conclusions/interpretation Lifetime risk of diabetes in metropolitan cities in India is alarming across the spectrum of weight and rises dramatically with higher BMI. Prevention of diabetes among metropolitan Indians of all ages is an urgent national priority, particularly given the rapid increase in urban obesogenic environments across the country.


2014 ◽  
Vol 18 (3) ◽  
pp. 252 ◽  
Author(s):  
Ambady Ramachandran ◽  
Chamukuttan Snehalatha

Author(s):  
Mette Aadahl ◽  
Anne H. Andreasen ◽  
Christina B. Petersen ◽  
Nidhi Gupta ◽  
Andreas Holtermann ◽  
...  

2013 ◽  
Vol 7 ◽  
pp. e97
Author(s):  
Jennie Brand-Miller ◽  
Stephen Colagiuri ◽  
Mikael Fogelholm ◽  
Edith Feskens ◽  
Margriet Westerterp-Plantenga ◽  
...  

2009 ◽  
Vol 8 (4) ◽  
pp. 169-175 ◽  
Author(s):  
Sheri R. Colberg ◽  
Carmine R. Grieco

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