The Gastric H/K ATPase in the Pathogenesis of Autoimmune Gastritis

2002 ◽  
pp. 107-114 ◽  
Author(s):  
Ban-Hock Toh ◽  
Mark Biondo ◽  
Aiden Marshall ◽  
Deanne Greenwood ◽  
John Sentry ◽  
...  
Keyword(s):  
Autoimmune Gastritis

Evidence for high Helicobacter pylori mucosal specific IgG secretion in autoimmune gastritis

2001 ◽  
Vol 120 (5) ◽  
pp. A708-A708
Author(s):  
G DORTA ◽  
D ANTOS ◽  
J RADKE ◽  
S MIEHLKE ◽  
J MARTINEK ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Autoimmune Gastritis ◽  
Specific Igg ◽  
Igg Secretion

Iron deficiency workup reveals high incidence of autoimmune gastritis with parietal cell antibody as reliable screening test

2017 ◽  
Vol 55 (05) ◽  
pp. e28-e56
Author(s):  
S Dabsch ◽  
M Resch ◽  
G Oberhuber ◽  
F Klinglmüller ◽  
A Gasche ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Parietal Cell ◽  
Screening Test ◽  
Autoimmune Gastritis ◽  
Cell Antibody ◽  
High Incidence ◽  
Parietal Cell Antibody

Sa1343 CLASSIFICATION OF AUTOIMMUNE GASTRITIS BASED ON THE STATUS OF POLYGLANDULAR POLYGLANDULAR AUTOIMMUNE SYNDROME

2020 ◽  
Vol 158 (6) ◽  
pp. S-324-S-325
Author(s):  
Takahisa Furuta ◽  
Takuma Kagami ◽  
Mihoko Yamade ◽  
Takahiro Suzuki ◽  
Tomohiro Higuchi ◽  
...  
Keyword(s):  
Autoimmune Gastritis ◽  
Polyglandular Autoimmune Syndrome ◽  
Autoimmune Syndrome ◽  
The Status

Mouse mammary tumor virus superantigens and murine autoimmune gastritis

1994 ◽  
Vol 107 (4) ◽  
pp. 924-933 ◽  
Author(s):  
Dirk Claeys ◽  
Ochine Karapetian ◽  
Emilia Saraga ◽  
Magali Schreyer ◽  
Jacques Louis ◽  
...  
Keyword(s):  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Autoimmune Gastritis ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus

Lack of uniformity in reporting autoimmune gastritis among a diverse group of pathologists

2021 ◽  
pp. 151840
Author(s):  
M. Suzanne Bloomquist ◽  
John Powell ◽  
Ramya Masand ◽  
Deepti Dhall ◽  
Dipti M. Karamchandani ◽  
...  
Keyword(s):  
Autoimmune Gastritis ◽  
Diverse Group

Helicobacter pylori in autoimmune gastritis

1991 ◽  
Vol 101 (6) ◽  
pp. 1759 ◽  
Author(s):  
Giulio Cariani ◽  
Gabriella Bonora ◽  
Alberto Vandelli ◽  
Guido Mazzoleni ◽  
Giovanni Fontana
Keyword(s):  
Helicobacter Pylori ◽  
Autoimmune Gastritis

scholarly journals Two Distinct Etiologies of Gastric Cancer: Infection and Autoimmunity

2021 ◽  
Vol 9 ◽  
Author(s):  
Stella G. Hoft ◽  
Christine N. Noto ◽  
Richard J. DiPaolo
Keyword(s):  
Gastric Cancer ◽  
T Cells ◽  
Gastric Adenocarcinoma ◽  
Inflammatory Diseases ◽  
The United States ◽  
Autoimmune Gastritis ◽  
Gastric Disease ◽  
Increased Risk ◽  
H Pylori ◽  
Gastrointestinal Ulceration

Gastric cancer is a leading cause of mortality worldwide. The risk of developing gastric adenocarcinoma, which comprises >90% of gastric cancers, is multifactorial, but most associated with Helicobacter pylori infection. Autoimmune gastritis is a chronic autoinflammatory syndrome where self-reactive immune cells are activated by gastric epithelial cell autoantigens. This cause of gastritis is more so associated with the development of neuroendocrine tumors. However, in both autoimmune and infection-induced gastritis, high risk metaplastic lesions develop within the gastric mucosa. This warrants concern for carcinogenesis in both inflammatory settings. There are many similarities and differences in disease progression between these two etiologies of chronic gastritis. Both diseases have an increased risk of gastric adenocarcinoma development, but each have their own unique comorbidities. Autoimmune gastritis is a primary cause of pernicious anemia, whereas chronic infection typically causes gastrointestinal ulceration. Both immune responses are driven by T cells, primarily CD4+ T cells of the IFN-γ producing, Th1 phenotype. Neutrophilic infiltrates help clear H. pylori infection, but neutrophils are not necessarily recruited in the autoimmune setting. There have also been hypotheses that infection with H. pylori initiates autoimmune gastritis, but the literature is far from definitive with evidence of infection-independent autoimmune gastric disease. Gastric cancer incidence is increasing among young women in the United States, a population at higher risk of developing autoimmune disease, and H. pylori infection rates are falling. Therefore, a better understanding of these two chronic inflammatory diseases is needed to identify their roles in initiating gastric cancer.

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