Role of Androgens and Extracellular Matrix in the Growth and Differentiation of Benign and Malignant Prostate Epithelial Cells

1991 ◽  
pp. 267-269 ◽  
Author(s):  
Edward R. Sherwood ◽  
Chau-Jye Fong ◽  
James M. Kozlowski ◽  
Chung Lee
Keyword(s):  
Extracellular Matrix ◽  
Epithelial Cells ◽  
Prostate Epithelial Cells ◽  
Malignant Prostate

scholarly journals Cell death in irradiated prostate epithelial cells: role of apoptotic and clonogenic cell kill

2003 ◽  
Vol 6 (1) ◽  
pp. 73-85 ◽  
Author(s):  
G P Bromfield ◽  
A Meng ◽  
P Warde ◽  
R G Bristow
Keyword(s):  
Cell Death ◽  
Epithelial Cells ◽  
Prostate Epithelial Cells ◽  
Cell Kill ◽  
Clonogenic Cell

scholarly journals Normal and Malignant Prostate Epithelial Cells Differ in Their Response to Hepatocyte Growth Factor/Scatter Factor

2001 ◽  
Vol 159 (2) ◽  
pp. 579-590 ◽  
Author(s):  
Glenn A. Gmyrek ◽  
Marc Walburg ◽  
Craig P. Webb ◽  
Hsiao-Man Yu ◽  
Xueke You ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epithelial Cells ◽  
Hepatocyte Growth Factor ◽  
Scatter Factor ◽  
Prostate Epithelial Cells ◽  
Hepatocyte Growth ◽  
Malignant Prostate

scholarly journals Transforming growth factor–β in tissue fibrosis

2020 ◽  
Vol 217 (3) ◽  
Author(s):  
Nikolaos G. Frangogiannis
Keyword(s):  
Extracellular Matrix ◽  
Growth Factor ◽  
Epithelial Cells ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Cell Types ◽  
Cellular Targets ◽  
Extracellular Matrix Molecules ◽  
Interacting Networks

TGF-β is extensively implicated in the pathogenesis of fibrosis. In fibrotic lesions, spatially restricted generation of bioactive TGF-β from latent stores requires the cooperation of proteases, integrins, and specialized extracellular matrix molecules. Although fibroblasts are major targets of TGF-β, some fibrogenic actions may reflect activation of other cell types, including macrophages, epithelial cells, and vascular cells. TGF-β–driven fibrosis is mediated through Smad-dependent or non-Smad pathways and is modulated by coreceptors and by interacting networks. This review discusses the role of TGF-β in fibrosis, highlighting mechanisms of TGF-β activation and signaling, the cellular targets of TGF-β actions, and the challenges of therapeutic translation.

STEM CELL FEATURES OF BENIGN AND MALIGNANT PROSTATE EPITHELIAL CELLS

1998 ◽  
pp. 2381-2392 ◽  
Author(s):  
ANGELO M. DE MARZO ◽  
WILLIAM G. NELSON ◽  
ALAN K. MEEKER ◽  
DONALD S. COFFEY
Keyword(s):  
Stem Cell ◽  
Epithelial Cells ◽  
Prostate Epithelial Cells ◽  
Malignant Prostate

STEM CELL FEATURES OF BENIGN AND MALIGNANT PROSTATE EPITHELIAL CELLS

1998 ◽  
Vol 160 (6 Part 2) ◽  
pp. 2381-2392 ◽  
Author(s):  
ANGELO M. DE MARZO ◽  
WILLIAM G. NELSON ◽  
ALAN K. MEEKER ◽  
DONALD S. COFFEY
Keyword(s):  
Stem Cell ◽  
Epithelial Cells ◽  
Prostate Epithelial Cells ◽  
Malignant Prostate
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