Interaction of RF and MW with the Living Systems: Research and Experience in China

Author(s):  
K. C. Yee
Author(s):  
Igor Gurevich

The work confirms the priority of information laws, which are the basis of physical informatics: the information laws (informatics laws) are defined and restrict the physical laws; the informatics laws have a general, universal character, and operate in all possible universes with different physical laws. Physical Informatics is the science of modern Information in physical and chemical systems, including Quantum Informatics, and is the basis for Informatics of the Living Systems.


Author(s):  
Igor Gurevich

The work confirms the priority of information laws, which are the basis of physical informatics: the information laws (informatics laws) are defined and restrict the physical laws; the informatics laws have a general, universal character, and operate in all possible universes with different physical laws. Physical Informatics is the science of modern Information in physical and chemical systems, including Quantum Informatics, and is the basis for Informatics of the Living Systems.


Many vitally important functions in living systems are carried out by metal ions held as complexes within organic ligands, the organic part of the molecule being a tetrapyrrolic macrocycle. Chlorophyll, haemoglobin, the cytochromes and vitamin B 12 all fall into this family of ‘pigments of life’, a list that emphasizes their central importance in living systems. Research on the biosynthesis of these pigments has involved the synergistic combination of synthesis, structure determination, carbon nuclear magnetic resonance and isotopic labelling with radioactive and stable isotopes in conjunction with enzymology and kinetics. The lecture describes the logical series of experiments based on these approaches which have led to a step-by-step knowledge of the biosynthesis of the parent macrocycle (uroporphyrinogen-III) from which the other pigments are derived. One main pathway from the parent macrocycle involves oxidative transformations and leads eventually to protohaem required inter alia for haemoglobin and myoglobin. The second important pathway makes use of C-methylation to convert the parent macrocycle through many stages finally into vitamin B 12 . The biosynthetic studies on vitamin B 12 are outlined with particular emphasis on the use of isotopic labelling with both radioactive and stable isotopes of carbon and hydrogen. Roughly two-thirds of the entire biosynthetic pathway to vitamin B 12 has now been elucidated. The scarcity of several of the known intermediates on the pathway severely hampers future researches and progress towards the total synthesis of these key materials is reviewed. Finally, the lecture brings out the evolutionary interest of what has been discovered about the biosynthesis of the pigments of life.


1997 ◽  
Vol 161 ◽  
pp. 437-442
Author(s):  
Salvatore Di Bernardo ◽  
Romana Fato ◽  
Giorgio Lenaz

AbstractOne of the peculiar aspects of living systems is the production and conservation of energy. This aspect is provided by specialized organelles, such as the mitochondria and chloroplasts, in developed living organisms. In primordial systems lacking specialized enzymatic complexes the energy supply was probably bound to the generation and maintenance of an asymmetric distribution of charged molecules in compartmentalized systems. On the basis of experimental evidence, we suggest that lipophilic quinones were involved in the generation of this asymmetrical distribution of charges through vectorial redox reactions across lipid membranes.


Author(s):  
Robert Corbett ◽  
Delbert E. Philpott ◽  
Sam Black

Observation of subtle or early signs of change in spaceflight induced alterations on living systems require precise methods of sampling. In-flight analysis would be preferable but constraints of time, equipment, personnel and cost dictate the necessity for prolonged storage before retrieval. Because of this, various tissues have been stored in fixatives and combinations of fixatives and observed at various time intervals. High pressure and the effect of buffer alone have also been tried.Of the various tissues embedded, muscle, cartilage and liver, liver has been the most extensively studied because it contains large numbers of organelles common to all tissues (Fig. 1).


1990 ◽  
Vol 45 (8) ◽  
pp. 980-981 ◽  
Author(s):  
Donald H. Ford

1976 ◽  
Vol 21 (4) ◽  
pp. 313-313
Author(s):  
KARL E. WEICK
Keyword(s):  

2009 ◽  
Author(s):  
Tim Kotnour ◽  
Kay Stanney ◽  
Rafael Landaeta ◽  
Laura Milham ◽  
Julie Drexler ◽  
...  

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