Creatinephosphokinase in Human Diploid Cell Lines

1975 ◽  
pp. 185-192
Author(s):  
M. Macek ◽  
H. Tomášová ◽  
J. Hurych ◽  
D. Řezáčová
Keyword(s):  
Cell Lines ◽  
Diploid Cell ◽  
Human Diploid Cell

Catalase turnover in human diploid cell cultures

1972 ◽  
Vol 73 (2) ◽  
pp. 399-409 ◽  
Author(s):  
W.J. Mellman ◽  
R.T. Schimke ◽  
L. Hayflick
Keyword(s):  
Cell Cultures ◽  
Diploid Cell ◽  
Human Diploid Cell

Antibody persistence, 32 years after post-exposure prophylaxis with human diploid cell rabies vaccine (HDCV)

Vaccine ◽  
2011 ◽  
Vol 29 (21) ◽  
pp. 3742-3745 ◽  
Author(s):  
Ahmad Fayaz ◽  
Susan Simani ◽  
Alireza Janani ◽  
Firouzeh Farahtaj ◽  
Peyvand Biglari ◽  
...  
Keyword(s):  
Diploid Cell ◽  
Rabies Vaccine ◽  
Post Exposure Prophylaxis ◽  
Human Diploid Cell ◽  
Post Exposure ◽  
Antibody Persistence ◽  
Exposure Prophylaxis

Quantitative cell fusion: the fusion sensitivity (FS) potential

1981 ◽  
Vol 49 (1) ◽  
pp. 87-97
Author(s):  
D. Rohme
Keyword(s):  
Cell Line ◽  
Cell Fusion ◽  
Cell Lines ◽  
Dose Response ◽  
Sendai Virus ◽  
Biological Significance ◽  
Diploid Cell ◽  
Mammalian Cell Lines ◽  
Virus Dose ◽  
A Cell

The dose response of Sendai virus-induced cell fusion was studied in 10 mammalian cell lines, comprising 5 continuous and 5 diploid cell lines originating from 5 species. The extent of fusion was calculated using a parameter directly proportional to the number of fusion events (t-parameter). At lower levels of fusion the dose response was found to be based on the same simple kinetic rules in all cell lines and was defined by the formula: t = FS. FAU/(I + FS. FAU), where FS (fusion sensitivity) is a cell-specific constant of the fusion rate and FAU (fusion activity units) is the virus dose. The FS potential of a cell line was determined as the linear regression coefficient of the fusion index (t/(I - t)) on the virus dose. At higher levels of fusion, when the fusion extent reached cell-line-specific maximal levels, the dose response was not as uniform. In general, and particularly in the cases of the diploid cell lines, these maximal levels were directly proportional to the FS potentials. Thus, it was concluded that the FS potential is the basic quantitative feature, which expresses the cellular fusion efficiency. The fact that FS varied extensively between cell lines, but at the same time apparently followed certain patterns (being higher in continuous compared to diploid cell lines and being related to the species of origin of the cells), emphasizes it biological significance as well as its possible usefulness in studies of the efficiency of various molecular interactions in the cell membrane/cytoskeleton system.

Inactivated Mayaro Vaccine Produced in Human Diploid Cell Cultures

1976 ◽  
Vol 141 (3) ◽  
pp. 163-166 ◽  
Author(s):  
David M. Robinson ◽  
Albert T. McManus ◽  
Francis E. Cole ◽  
Carl E. Pedersen
Keyword(s):  
Cell Cultures ◽  
Diploid Cell ◽  
Human Diploid Cell

Clinical Experience With a Human Diploid Cell Rabies Vaccine

JAMA ◽  
1980 ◽  
Vol 244 (8) ◽  
pp. 781 ◽  
Author(s):  
Larry J. Anderson
Keyword(s):  
Clinical Experience ◽  
Diploid Cell ◽  
Rabies Vaccine ◽  
Human Diploid Cell

scholarly journals Biocompatibility assessment of glas ionomer cement: Test of cytotoxicity

2002 ◽  
Vol 49 (3-4) ◽  
pp. 75-80 ◽  
Author(s):  
Dejan Markovic
Keyword(s):  
Composite Material ◽  
Cytotoxic Effect ◽  
Dental Materials ◽  
Cost Effective ◽  
Diploid Cell ◽  
Test Results ◽  
Human Diploid Cell ◽  
Significant Difference ◽  
Materials Used ◽  
Ionomer Cement

Evaluation o f cytotoxicity is a first step in assessment of dental materials biocompatibility. Necessity for unique criteria in researches resulted in international standard methodology (ISO). The aim of this study was to assess the cytotoxicity of four restorative materials (three glas ionomer cements and one composite material) and to define adventages and disadventages of common ISO methodology for evaluation of this aspect of dental materials biocompatibility. Research was designed according to ISO/TC 106/1995 and ISO/ 10993-5/1994 methodology. Materials used in this investigation were Fuji IILC (GC), Vitiemer (3M), Ionosit fill (DMG-Hamburg), Luxat (DMG-Hamburg). Evaluation of cytotoxicity was carried out on standardized Human Diploid Cell Lung WI-38. Obtained results showed expressive cytotoxic effect of all investigated materials without statisticaly significant difference. Estimation of material biocompatibility and assessment of obtained results can be made only after establishment of correlation with test results. Common ISO methodology is simple for conductance and reproduction, and use of cell cultures in researches is painless, cost effective and without moral or ethical dilemma.

A comparative field trial of five measles vaccines produced in human diploid cell, MRC-5

1977 ◽  
Vol 5 (1) ◽  
pp. 1-18 ◽  
Author(s):  
H. Mirchamsy ◽  
A. Shafyi ◽  
S. Bahrami ◽  
M. Kamali ◽  
P. Nazari ◽  
...  
Keyword(s):  
Field Trial ◽  
Diploid Cell ◽  
Human Diploid Cell
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