Response to Exogenous 1,25(OH)2D during a Low-Calcium Diet in Normal Subjects and Idiopathic Renal-Stone Formers

Urolithiasis ◽  
1989 ◽  
pp. 611-613
Author(s):  
J. R. Weisinger ◽  
E. Bellorín-Font ◽  
A. Aveledo ◽  
P. Durrego ◽  
G. Gonzalez ◽  
...  
Keyword(s):  
Renal Stone ◽  
Normal Subjects ◽  
Calcium Diet ◽  
Low Calcium Diet ◽  
Low Calcium ◽  
Stone Formers

scholarly journals PTH and 1.25 vitamin D response to a low-calcium diet is associated with bone mineral density in renal stone formers

2008 ◽  
Vol 23 (8) ◽  
pp. 2563-2570 ◽  
Author(s):  
A. Pasch ◽  
F. J. Frey ◽  
U. Eisenberger ◽  
M. G. Mohaupt ◽  
O. Bonny
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Renal Stone ◽  
Mineral Density ◽  
Calcium Diet ◽  
Low Calcium Diet ◽  
Low Calcium ◽  
Stone Formers

Involvement of low-calcium diet in the reduced bone mineral content of idiopathic renal stone formers

1990 ◽  
Vol 46 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Michel Fuss ◽  
Thierry Pepersack ◽  
Jean Van Geel ◽  
Jacques Corvilain ◽  
Jean-Claude Vandewalle ◽  
...  
Keyword(s):  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Renal Stone ◽  
Calcium Diet ◽  
Low Calcium Diet ◽  
Low Calcium ◽  
Stone Formers

scholarly journals Changes in urinary risk profile after short-term low sodium and low calcium diet in recurrent Swiss kidney stone formers

2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Harald Seeger ◽  
Andrea Kaelin ◽  
Pietro M. Ferraro ◽  
Damian Weber ◽  
Philippe Jaeger ◽  
...  
Keyword(s):  
Kidney Stone ◽  
Risk Profile ◽  
Short Term ◽  
Calcium Diet ◽  
Low Sodium ◽  
Low Calcium Diet ◽  
Low Calcium ◽  
Stone Formers

scholarly journals Icariin protects against cage layer osteoporosis by intervening in steroid biosynthesis and glycerophospholipid metabolism

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Zhengwang Yu ◽  
Jie Huang ◽  
Zhongxin Zhou
Keyword(s):  
Metabolic Diseases ◽  
Chinese Herb ◽  
Therapeutic Effects ◽  
Mineral Density ◽  
Steroid Biosynthesis ◽  
Metabolic Pathway Analysis ◽  
Effective Prevention ◽  
Calcium Diet ◽  
Low Calcium Diet ◽  
Low Calcium

AbstractCage layer osteoporosis (CLO) is a common bone metabolism disease in the breeding industry of China. However, effective prevention for CLO has not been developed. Icariin (ICA), the main bioactive component of the Chinese herb Epimedium, has been shown to have good therapeutic effects on bone-related diseases. In this study, the effects of ICA were further evaluated in a low-calcium diet-induced CLO, and a serum metabolomics assay was performed to understand the underlying mechanisms. A total of 144 31-wk-old Lohmann pink-shell laying hens were randomly allocated to 4 groups with 6 replicates of 6 hens per replicate. The 4 dietary treatment groups consisted of a basal diet (3.5% calcium), a low-calcium diet (2.0% calcium), and a low-calcium diet supplemented with 0.5 or 2.0 g/kg ICA. The results showed that ICA exerted good osteoprotective effects on low-calcium diet-induced CLO. ICA significantly increased femur bone mineral density, improved bone microstructure, decreased bone metabolic level, and upregulated mRNA expression of bone formation genes in femoral bone tissue. Serum untargeted metabolomics analysis showed that 8 metabolite levels were significantly changed after ICA treatment, including increased contents of 7-dehydrocholesterol, 7-oxocholesterol, desmosterol, PC (18:1(9Z)/18:1(9Z)), PS (18:0/18:1(9Z)), N,N-dimethylaniline and 2-hydroxy-butanoic acid and decreased N2,N2-dimethylguanosine. Metabolic pathway analysis based on the above 8 metabolites indicated that ICA mainly perturbed steroid biosynthesis and glycerophospholipid metabolism. These findings suggest that ICA can effectively prevent bone loss in low-calcium diet-induced CLO by mediating steroid biosynthesis and glycerophospholipid metabolism and provide new information for the regulation of bone metabolic diseases.

Low-calcium diet increases blood pressure and alters peripheral but not central angiotensin II binding sites in rats

1989 ◽  
Vol 7 (5) ◽  
pp. 423-427 ◽  
Author(s):  
Samarendra N. Baksi ◽  
Raymond H. Abhold ◽  
Robert C. Speth
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Binding Sites ◽  
Calcium Diet ◽  
Low Calcium Diet ◽  
Low Calcium
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