Factors Influencing the Urinary Excretion of Phenol and Cresols

Author(s):  
F. Sanguinetti ◽  
M. C. Sanguinetti ◽  
S. Mantovani ◽  
C. Melandri
1970 ◽  
Vol 30 (3) ◽  
pp. 316-324 ◽  
Author(s):  
ANDREW L. TAYLOR ◽  
BERNARD B. DAVIS ◽  
L. GREGORY PAWLSON ◽  
JOHN B. JOSIMOVICH ◽  
DANIEL H. MINTZ

1959 ◽  
Vol 196 (6) ◽  
pp. 1352-1355 ◽  
Author(s):  
G. M. Krise ◽  
C. M. Williams

Normal albino rats exposed to 1500 r of whole-body Co60 gamma radiation were found to have a significant increase in urinary creatine excretion for the first 3 postirradiation days. Adrenalectomized rats, irradiated at 8 days postoperatively, did not show a creatinuria significantly greater than nonirradiated controls. Thyroparathyroidectomized rats, irradiated at 8 days postoperatively, did not have a significant increase in urinary creatine excretion over that of nonirradiated fasted controls. There were no significant increases in polyuria or polydipsia on the 1st postirradiation day in either the adrenalectomized or thyroparathyroidectomized rats. The intramuscular injection of 500 mu of the antidiuretic hormone vasopressin (Pitressin tannate) in oil inhibited postirradiation polydipsia and polyuria in normal rats but significantly increased the urinary excretion of creatine over that of irradiated noninjected controls.


1973 ◽  
Vol 44 (3) ◽  
pp. 253-265 ◽  
Author(s):  
Mary M. Townshend ◽  
A. J. Smith

1. The 24 h urinary excretion of noradrenaline and adrenaline is significantly lower in recumbent than ambulant normal subjects. 2. A diurnal variation exists in catecholamine excretion, the lowest values occurring during sleep. 3. Diurnal variation in sodium excretion parallels that in noradrenaline and adrenaline loss but the cycles can be separated by acute alterations in sleep/awake pattern. 4. Diurnal variation is lost during exercise, after myocardial infarction and was absent pre-operatively in a patient with a phaeochromocytoma. 5. Acute alterations in renal blood flow, diuresis, natriuresis and urinary acidification do not alter catecholamine excretion significantly. 6. Urinary catecholamine excretion is related to physical activity and wakefulness; the normal diurnal variation is easily overriden by sustained sympatho-adrenal activity. Alterations in renal function in exercise or after myocardial infarction do not account for the observed increases in catecholamine excretion.


Author(s):  
Julie A. Martini ◽  
Robert H. Doremus

Tracy and Doremus have demonstrated chemical bonding between bone and hydroxylapatite with transmission electron microscopy. Now researchers ponder how to improve upon this bond in turn improving the life expectancy and biocompatibility of implantable orthopedic devices.This report focuses on a study of the- chemical influences on the interfacial integrity and strength. Pure hydroxylapatite (HAP), magnesium doped HAP, strontium doped HAP, bioglass and medical grade titanium cylinders were implanted into the tibial cortices of New Zealand white rabbits. After 12 weeks, the implants were retrieved for a scanning electron microscopy study coupled with energy dispersive spectroscopy.Following sacrifice and careful retrieval, the samples were dehydrated through a graduated series starting with 50% ethanol and continuing through 60, 70, 80, 90, 95, and 100% ethanol over a period of two days. The samples were embedded in LR White. Again a graduated series was used with solutions of 50, 75 and 100% LR White diluted in ethanol.


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