Biofilm Matrix-Degrading Enzymes

2014 ◽  
pp. 203-213 ◽  
Author(s):  
Jeffrey B. Kaplan
Keyword(s):  
Degrading Enzymes ◽  
Matrix Degrading Enzymes ◽  
Biofilm Matrix

GENE EXPRESSION OF MATRIX-DEGRADING ENZYMES IN PATELLAR TENDINOPATHY

2013 ◽  
Vol 47 (9) ◽  
pp. e2.3-e2
Author(s):  
T Samiric ◽  
C J Handley ◽  
J Cook ◽  
J Parkinson
Keyword(s):  
Gene Expression ◽  
Patellar Tendinopathy ◽  
Degrading Enzymes ◽  
Matrix Degrading Enzymes

scholarly journals Strain variation in Bacillus cereus biofilms and their susceptibility to extracellular matrix-degrading enzymes

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0245708
Author(s):  
Eun Seob Lim ◽  
Seung-Youb Baek ◽  
Taeyoung Oh ◽  
Minseon Koo ◽  
Joo Young Lee ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Bacillus Cereus ◽  
Biofilm Formation ◽  
Dnase I ◽  
Extracellular Dna ◽  
Proteinase K ◽  
Strain Variation ◽  
Protein Ratio ◽  
Degrading Enzymes ◽  
Matrix Degrading Enzymes

Bacillus cereus is a foodborne pathogen and can form biofilms on food contact surfaces, which causes food hygiene problems. While it is necessary to understand strain-dependent variation to effectively control these biofilms, strain-to-strain variation in the structure of B. cereus biofilms is poorly understood. In this study, B. cereus strains from tatsoi (BC4, BC10, and BC72) and the ATCC 10987 reference strain were incubated at 30°C to form biofilms in the presence of the extracellular matrix-degrading enzymes DNase I, proteinase K, dispase II, cellulase, amyloglucosidase, and α-amylase to assess the susceptibility to these enzymes. The four strains exhibited four different patterns in terms of biofilm susceptibility to the enzymes as well as morphology of surface-attached biofilms or suspended cell aggregates. DNase I inhibited the biofilm formation of strains ATCC 10987 and BC4 but not of strains BC10 and BC72. This result suggests that some strains may not have extracellular DNA, or their extracellular DNA may be protected in their biofilms. In addition, the strains exhibited different patterns of susceptibility to protein- and carbohydrate-degrading enzymes. While other strains were resistant, strains ATCC 10987 and BC4 were susceptible to cellulase, suggesting that cellulose or its similar polysaccharides may exist and play an essential role in their biofilm formation. Our compositional and imaging analyses of strains ATCC 10987 and BC4 suggested that the physicochemical properties of their biofilms are distinct, as calculated by the carbohydrate to protein ratio. Taken together, our study suggests that the extracellular matrix of B. cereus biofilms may be highly diverse and provides insight into the diverse mechanisms of biofilm formation among B. cereus strains.

scholarly journals Lentinan Inhibits AGE-Induced Inflammation and the Expression of Matrix-Degrading Enzymes in Human Chondrocytes

2020 ◽  
Vol Volume 14 ◽  
pp. 2819-2829
Author(s):  
Zhaozhen Zhang ◽  
Zhuqing Zha ◽  
Zhiwei Zhao ◽  
Wenjing Liu ◽  
Wuyin Li
Keyword(s):  
Human Chondrocytes ◽  
Degrading Enzymes ◽  
Matrix Degrading Enzymes

DIFFERENTIAL INVOLVEMENT OF MATRIX DEGRADING ENZYMES IN ANTIHYPERTENSIVE-DRUG INDUCED VASCULAR STRUCTURAL CHANGES

2004 ◽  
Vol 13 (3) ◽  
pp. 120
Author(s):  
Martin J Shoichet ◽  
Taben M Hale ◽  
Charles H Graham ◽  
Terri L Bushfield ◽  
Michael A Adams
Keyword(s):  
Antihypertensive Drug ◽  
Structural Changes ◽  
Drug Induced ◽  
Degrading Enzymes ◽  
Differential Involvement ◽  
Matrix Degrading Enzymes
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