Pulmonary Rehabilitation: Targeting the Systemic Manifestations of COPD

MODERN ASPECTS OF PULMONARY REHABILITATION IN THE CONTEXT OF THE COVID-19 PANDEMIC І. А. Iliuk, K. P. Postovitenko, I. V. Baranova, S. I. Leshchenko, S. V. Shevchuk, L. P. Denyshchych, I. V Kurilenko, N. M. Prykhodko Abstract It is well known that patients who have had a coronavirus infection need in rehabilitation measures to eliminate the consequences of the disease. However, the data about methods of medical rehabilitation and their effectiveness in such patients are limited, since this disease is new and insufficiently studied. It is believed that medical rehabilitation in COVID-19 convalescents should be comprehensive and aimed at optimizing the patient’s functional capabilities, reducing the cost of treatment, by stabilizing and reducing the systemic manifestations of the disease. This article is devoted to the problem of pulmonary rehabilitation in the context of the COVID-19 pandemic. This area of medicine pursues important goals - reducing the symptoms of the disease, improving the quality of life and increasing the patient’s physical and emotional participation in daily life. The article lists the main methods of pulmonary rehabilitation. The choice the correct methods and personalization of rehabilitation programs, taking into account the individual clinical situation, can prevent the appearance of functional disorders and improve the quality of life of the patients after COVID-19. Key words: COVID-19, pulmonary rehabilitation, quality of life. Ukr. Pulmonol. J. 2020;29(3):66–72:

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A rapid method for the direct identification of paramyxovirus in canine CSF by ultracentrifugation and negative staining as a rule out for distemper

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100160522 ◽

1990 ◽

Vol 48 (3) ◽

pp. 594-595

Author(s):

W.L. Steffens ◽

M.B. Ard ◽

C.E. Greene ◽

A. Jaggy

Keyword(s):

Subacute Sclerosing Panencephalitis ◽

Clinical Signs ◽

Viral Disease ◽

Etiologic Agent ◽

Mucosal Inflammation ◽

Worldwide Distribution ◽

Negative Stain ◽

Viral Particles ◽

Systemic Manifestations ◽

Rule Out

Canine distemper is a multisystemic contagious viral disease having a worldwide distribution, a high mortality rate, and significant central neurologic system (CNS) complications. In its systemic manifestations, it is often presumptively diagnosed on the basis of clinical signs and history. Few definitive antemortem diagnostic tests exist, and most are limited to the detection of viral antigen by immunofluorescence techniques on tissues or cytologic specimens or high immunoglobulin levels in CSF (cerebrospinal fluid). Diagnosis of CNS distemper is often unreliable due to the relatively low cell count in CSF (<50 cells/μl) and the binding of blocking immunoglobulins in CSF to cell surfaces. A more reliable and definitive test might be possible utilizing direct morphologic detection of the etiologic agent. Distemper is the canine equivalent of human measles, in that both involve a closely related member of the Paramyxoviridae, both produce mucosal inflammation, and may produce CNS complications. In humans, diagnosis of measles-induced subacute sclerosing panencephalitis is through negative stain identification of whole or incomplete viral particles in patient CSF.

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Pulmonary rehabilitation in COPD

Therapeutische Umschau ◽

10.1024/0040-5930.56.3.131 ◽

1999 ◽

Vol 56 (3) ◽

pp. 131-135

Author(s):

Villiger

Keyword(s):

Pulmonary Rehabilitation ◽

Psychosoziale Betreuung

Die Pulmonale Rehabilitation (PR) ist ein wichtiger Bestandteil der Behandlung der chronisch obstruktiven Lungenkrankheiten (COPD und Emphysem). Es ist heute wissenschaftlich erwiesen und durch Metaanalysen bestätigt, daß diese Programme die Leistungsfähigkeit und die Lebensqualität verbessern sowie die Symptome reduzieren. Weiterhin bestehen Hinweise, daß durch die PR der Medikamentenverbrauch reduziert und das Überleben verbessert werden kann. Die PR ist multidisziplinär. Von zentraler Bedeutung sind neben der Medizinischen Trainingstherapie (Ausdauer/Kraft) Physiotherapie, Patientenschulung, psychosoziale Betreuung und Ernährungsberatung. Die PR scheint besonders geeignet für Patienten mit geringer Leistungsfähigkeit, Muskelschwäche, ausgeprägten subjektiven Symptomen und schlechter Lebensqualität. Der Ort der Rehabilitation richtet sich nach dem Schweregrad der Symptome, den Anforderungen an das Reha-Team und den lokalen Möglichkeiten.

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Pulmonary rehabilitation may modestly improve anxiety and depression in adults with chronic obstructive pulmonary disease

10.3310/signal-000794 ◽

2019 ◽

Author(s):

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Pulmonary Disease ◽

Pulmonary Rehabilitation ◽

Anxiety And Depression ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease

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New therapeutic approaches for polymyositis and dermatomyositis

Orvosi Hetilap ◽

10.1556/oh.2011.29176 ◽

2011 ◽

Vol 152 (39) ◽

pp. 1552-1559 ◽

Cited By ~ 2

Author(s):

Katalin Dankó ◽

Melinda Vincze

Keyword(s):

Immunosuppressive Agents ◽

Inflammatory Myopathy ◽

Proximal Muscle ◽

Therapeutic Approaches ◽

First Line ◽

New Therapeutic Approaches ◽

Remission Period ◽

Immune Mediated ◽

Systemic Manifestations ◽

Line Of Therapy

Inflammatory myopathies are chronic, immune-mediated diseases characterized with progressive proximal muscle weakness. They encompass a variety of syndromes with protean manifestations. The aims of therapy are to increase muscle strength, prevent the development of contractures, and to manage the systemic manifestations of the disease. This is a complex treatment which requires routine and wide knowledge. The most important task is to recognize the disease and guide the patient to immunologic center. Although the first line of therapy continues to include corticosteroids, there are a multitude of agents available for treating patients with myositis. There are several different immunosuppressive agents which may be applied alone or in combination with each other, as well as an increasing number of novel and exciting biologic agents targeting molecules participating in the pathogenesis of inflammatory myopathy. Physiotherapy and rehabilitation in the remission period may significantly improve the functional outcome of patients with these disorders. Orv. Hetil., 2011, 152, 1552–1559.

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