Liquid Chromatography for Plant Metabolite Profiling in the Field of Drug Discovery

Natural Products as Source of Molecules with Therapeutic Potential ◽

10.1007/978-3-030-00545-0_3 ◽

2018 ◽

pp. 73-109

Author(s):

Luiz Carlos Klein-Júnior ◽

Johan Viaene ◽

Amorn Slosse ◽

Yvan Vander Heyden

Keyword(s):

Liquid Chromatography ◽

Drug Discovery ◽

Metabolite Profiling ◽

Plant Metabolite

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Liquid chromatography coupled to mass spectrometry for metabolite profiling in the field of drug discovery

Expert Opinion on Drug Discovery ◽

10.1080/17460441.2019.1582638 ◽

2019 ◽

Vol 14 (5) ◽

pp. 469-483 ◽

Cited By ~ 4

Author(s):

Javier Saurina ◽

Sonia Sentellas

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Discovery ◽

Metabolite Profiling

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A systematic approach to development of analytical scale and microflow-based liquid chromatography coupled to mass spectrometry metabolomics methods to support drug discovery and development

Journal of Chromatography A ◽

10.1016/j.chroma.2021.462047 ◽

2021 ◽

Vol 1642 ◽

pp. 462047

Author(s):

Sarah Geller ◽

Harvey Lieberman ◽

Alla Kloss ◽

Alexander R. Ivanov

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Discovery ◽

Systematic Approach ◽

Drug Discovery And Development ◽

Analytical Scale

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Active fragments-guided drug discovery and design of selective tropane alkaloids using ultra-high performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry coupled with virtual calculation and biological evaluation

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-016-0043-6 ◽

2016 ◽

Vol 409 (4) ◽

pp. 1145-1157 ◽

Cited By ~ 9

Author(s):

Mengge Zhou ◽

Xiaoyao Ma ◽

Jixue Sun ◽

Guoyu Ding ◽

Qingxin Cui ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Drug Discovery ◽

Tandem Mass Spectrometry ◽

High Performance ◽

Tropane Alkaloids ◽

Biological Evaluation ◽

Tandem Mass ◽

Active Fragments

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An electrospray ionisation tandem mass spectrometric investigation of selected psychoactive pharmaceuticals and its application in drug and metabolite profiling by liquid chromatography/electrospray ionisation tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3060 ◽

2007 ◽

Vol 21 (13) ◽

pp. 2031-2038 ◽

Cited By ~ 19

Author(s):

Bernadette Doherty ◽

Virginia Rodriguez ◽

Julian C. Leslie ◽

Stephen McClean ◽

W. Franklin Smyth

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Profiling ◽

Mass Spectrometric ◽

Tandem Mass ◽

Spectrometric Investigation ◽

Mass Spectrometric Investigation ◽

Electrospray Ionisation ◽

Tandem Mass Spectrometric

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Application of High Performance Liquid Chromatography for the Measurements of Lipophilicity and Biomimetic Binding Properties in Drug Discovery

Physico-Chemical Methods in Drug Discovery and Development ◽

10.5599/obp.7.2 ◽

2012 ◽

pp. 61-119

Author(s):

Klara Valko

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Drug Discovery ◽

High Performance ◽

Binding Properties

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Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography–atmospheric pressure ionization tandem mass spectrometry method

Journal of Chromatography B ◽

10.1016/s1570-0232(02)00061-2 ◽

2002 ◽

Vol 772 (1) ◽

pp. 89-98 ◽

Cited By ~ 8

Author(s):

Lawrence F. Colwell ◽

Constantin S. Tamvakopoulos ◽

Pei Ran Wang ◽

James V. Pivnichny ◽

Thomas L. Shih

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Discovery ◽

Atmospheric Pressure ◽

Tandem Mass ◽

Atmospheric Pressure Ionization ◽

Spectrometry Method ◽

Pharmacokinetic Screening ◽

Selection Of ◽

Ionization Tandem Mass Spectrometry

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High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS)-Based Drug Metabolite Profiling

Methods in Molecular Biology - Metabolic Profiling ◽

10.1007/978-1-61737-985-7_10 ◽

2010 ◽

pp. 173-190 ◽

Cited By ~ 9

Author(s):

Ian D. Wilson

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Metabolite Profiling ◽

High Performance ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Drug Metabolite

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Identification and metabolite profiling of alkaloids in aerial parts of Papaver rhoeas by liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Journal of Separation Science ◽

10.1002/jssc.201701402 ◽

2018 ◽

Vol 41 (12) ◽

pp. 2517-2527 ◽

Cited By ~ 10

Author(s):

Jae-Hyeon Oh ◽

In Jin Ha ◽

Min Young Lee ◽

Eun-Ok Kim ◽

Dain Park ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Profiling ◽

Time Of Flight ◽

Tandem Mass ◽

Papaver Rhoeas ◽

Aerial Parts

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Metabolite profiling and quantification of phytochemicals of Tianma–Gouteng granule in human and rat urine using ultra high performance liquid chromatography coupled with tandem mass spectrometry

Journal of Separation Science ◽

10.1002/jssc.201900029 ◽

2019 ◽

Vol 42 (17) ◽

pp. 2762-2770 ◽

Cited By ~ 1

Author(s):

Hongye Zhang ◽

Lu Wang ◽

Bin Lu ◽

Wen Qi ◽

Fuying Jiao ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Profiling ◽

High Performance ◽

Tandem Mass ◽

Rat Urine

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Open-access liquid chromatography/mass spectrometry in a drug discovery environment

Journal of Mass Spectrometry ◽

10.1002/jms.360 ◽

2002 ◽

Vol 37 (9) ◽

pp. 889-896 ◽

Cited By ~ 23

Author(s):

Larry M. Mallis ◽

Ani B. Sarkahian ◽

John M. Kulishoff ◽

William L. Watts

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Discovery ◽

Open Access ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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