Microfluidic Devices and Three Dimensional-Printing Strategies for in vitro Models of Bone

2020 ◽  
pp. 1-14
Author(s):  
F. Raquel Maia ◽  
Rui L. Reis ◽  
Vitor M. Correlo ◽  
Joaquim M. Oliveira
Keyword(s):  
Three Dimensional ◽  
Microfluidic Devices ◽  
In Vitro Models ◽  
Three Dimensional Printing ◽  
Dimensional Printing

Anti-Reflux Ureteral Stent with Polymeric Flap Valve Using Three-Dimensional Printing: An In Vitro Study

2015 ◽  
Vol 29 (8) ◽  
pp. 933-938 ◽  
Author(s):  
Chang-Ju Park ◽  
Hyeon-Woo Kim ◽  
Sangdo Jeong ◽  
Seungwan Seo ◽  
Yangkyu Park ◽  
...  
Keyword(s):  
Three Dimensional ◽  
In Vitro Study ◽  
Vitro Study ◽  
Ureteral Stent ◽  
Three Dimensional Printing ◽  
Dimensional Printing ◽  
Flap Valve

Study on Biodegradable Implant with Poly (l-Lactic Acid) and its Releasing Character In Vitro

2011 ◽  
Vol 236-238 ◽  
pp. 2744-2747
Author(s):  
Wei Dong Huang ◽  
Sheng Fang Li ◽  
Tao Zou ◽  
Xian You Xia
Keyword(s):  
Three Dimensional ◽  
Environmental Scanning ◽  
Biodegradable Implant ◽  
Three Dimensional Printing ◽  
Novel Technique ◽  
Single Form ◽  
Conventional Technology ◽  
Dimensional Printing ◽  
Scanning Electron

To elucidate the effects of implants fabricated by three-dimensional printing (3DP) technologies, a novel technique enables the complex implant release profiles, precise dosage control and rapid formulation in a single form. In this study, a unique implant with polylactic acid-based polymer powders was developed by the process. Test of the morphology and the releasing experiments in vitro of the implants were done to evaluate the implant devices. At about 100-day release of the implants in vitro, the drug concentration was measured and the profiles were made. The morphology of the implants of both technologies was characterized by three dimensional stereoscopy and environmental scanning electron microscope. The release behaviour and the microstructure were detected to compare the effects. 3DP technology allows the design and fabrication of implants with a novel micro- and macro-architecture which cannot be fabricated or may be fabricated with many difficulties in conventional technology.

scholarly journals Three-Dimensional Printed Devices in Droplet Microfluidics

Micromachines ◽  
2019 ◽  
Vol 10 (11) ◽  
pp. 754 ◽  
Author(s):  
Jia Ming Zhang ◽  
Qinglei Ji ◽  
Huiling Duan
Keyword(s):  
Three Dimensional ◽  
Microfluidic Devices ◽  
Droplet Formation ◽  
Droplet Microfluidics ◽  
Current Development ◽  
Three Dimensional Printing ◽  
The Cost ◽  
Novel Structures ◽  
Dimensional Printing

Droplet microfluidics has become the most promising subcategory of microfluidics since it contributes numerous applications to diverse fields. However, fabrication of microfluidic devices for droplet formation, manipulation and applications is usually complicated and expensive. Three-dimensional printing (3DP) provides an exciting alternative to conventional techniques by simplifying the process and reducing the cost of fabrication. Complex and novel structures can be achieved via 3DP in a simple and rapid manner, enabling droplet microfluidics accessible to more extensive users. In this article, we review and discuss current development, opportunities and challenges of applications of 3DP to droplet microfluidics.

Behavior of capillary valves in centrifugal microfluidic devices prepared by three-dimensional printing

2010 ◽  
Vol 10 (4) ◽  
pp. 877-888 ◽  
Author(s):  
Jessica L. Moore ◽  
Austin McCuiston ◽  
Isaac Mittendorf ◽  
Rudy Ottway ◽  
R. Daniel Johnson
Keyword(s):  
Three Dimensional ◽  
Microfluidic Devices ◽  
Three Dimensional Printing ◽  
Dimensional Printing

scholarly journals Tissue engineering and surgery: from translational studies to human trials

2017 ◽  
Vol 2 (4) ◽  
pp. 189-202 ◽  
Author(s):  
Jan Jeroen Vranckx ◽  
Margot Den Hondt
Keyword(s):  
Tissue Engineering ◽  
Wound Repair ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Engineering Sciences ◽  
Custom Made ◽  
Intrinsic Complexity ◽  
Dimensional Printing ◽  
Extensive Burn

AbstractTissue engineering was introduced as an innovative and promising field in the mid-1980s. The capacity of cells to migrate and proliferate in growth-inducing medium induced great expectancies on generating custom-shaped bioconstructs for tissue regeneration. Tissue engineering represents a unique multidisciplinary translational forum where the principles of biomaterial engineering, the molecular biology of cells and genes, and the clinical sciences of reconstruction would interact intensively through the combined efforts of scientists, engineers, and clinicians. The anticipated possibilities of cell engineering, matrix development, and growth factor therapies are extensive and would largely expand our clinical reconstructive armamentarium. Application of proangiogenic proteins may stimulate wound repair, restore avascular wound beds, or reverse hypoxia in flaps. Autologous cells procured from biopsies may generate an ‘autologous’ dermal and epidermal laminated cover on extensive burn wounds. Three-dimensional printing may generate ‘custom-made’ preshaped scaffolds – shaped as a nose, an ear, or a mandible – in which these cells can be seeded. The paucity of optimal donor tissues may be solved with off-the-shelf tissues using tissue engineering strategies. However, despite the expectations, the speed of translation of in vitro tissue engineering sciences into clinical reality is very slow due to the intrinsic complexity of human tissues. This review focuses on the transition from translational protocols towards current clinical applications of tissue engineering strategies in surgery.

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