A Novel Method for Extracting High-Quality RR Intervals from Noisy Single-Lead ECG Signals

Author(s):  
Shan Xue ◽  
Leirong Tian ◽  
Zhilin Gao ◽  
Xingran Cui
2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
Tng C. H. John ◽  
Edmond C. Prakash ◽  
Narendra S. Chaudhari

This paper proposes a novel method to generate strategic team AI pathfinding plans for computer games and simulations using probabilistic pathfinding. This method is inspired by genetic algorithms (Russell and Norvig, 2002), in that, a fitness function is used to test the quality of the path plans. The method generates high-quality path plans by eliminating the low-quality ones. The path plans are generated by probabilistic pathfinding, and the elimination is done by a fitness test of the path plans. This path plan generation method has the ability to generate variation or different high-quality paths, which is desired for games to increase replay values. This work is an extension of our earlier work on team AI: probabilistic pathfinding (John et al., 2006). We explore ways to combine probabilistic pathfinding and genetic algorithm to create a new method to generate strategic team AI pathfinding plans.


2022 ◽  
Vol 40 (4) ◽  
pp. 1-45
Author(s):  
Weiren Yu ◽  
Julie McCann ◽  
Chengyuan Zhang ◽  
Hakan Ferhatosmanoglu

SimRank is an attractive link-based similarity measure used in fertile fields of Web search and sociometry. However, the existing deterministic method by Kusumoto et al. [ 24 ] for retrieving SimRank does not always produce high-quality similarity results, as it fails to accurately obtain diagonal correction matrix  D . Moreover, SimRank has a “connectivity trait” problem: increasing the number of paths between a pair of nodes would decrease its similarity score. The best-known remedy, SimRank++ [ 1 ], cannot completely fix this problem, since its score would still be zero if there are no common in-neighbors between two nodes. In this article, we study fast high-quality link-based similarity search on billion-scale graphs. (1) We first devise a “varied- D ” method to accurately compute SimRank in linear memory. We also aggregate duplicate computations, which reduces the time of [ 24 ] from quadratic to linear in the number of iterations. (2) We propose a novel “cosine-based” SimRank model to circumvent the “connectivity trait” problem. (3) To substantially speed up the partial-pairs “cosine-based” SimRank search on large graphs, we devise an efficient dimensionality reduction algorithm, PSR # , with guaranteed accuracy. (4) We give mathematical insights to the semantic difference between SimRank and its variant, and correct an argument in [ 24 ] that “if D is replaced by a scaled identity matrix (1-Ɣ)I, their top-K rankings will not be affected much”. (5) We propose a novel method that can accurately convert from Li et al.  SimRank ~{S} to Jeh and Widom’s SimRank S . (6) We propose GSR # , a generalisation of our “cosine-based” SimRank model, to quantify pairwise similarities across two distinct graphs, unlike SimRank that would assess nodes across two graphs as completely dissimilar. Extensive experiments on various datasets demonstrate the superiority of our proposed approaches in terms of high search quality, computational efficiency, accuracy, and scalability on billion-edge graphs.


Proceedings ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 13
Author(s):  
Diogo Tecelão ◽  
Peter Charlton

Hospital patients recovering from major cardiac surgery are at risk of paroxysmal atrial fibrillation (AF), an arrhythmia which can be life-threatening. Wearable sensors are routinely used for electrocardiogram (ECG) monitoring in patients at risk of AF, providing real-time AF detection. However, wearable sensors could have greater impact if used to identify the subtle changes in P-wave morphology which precede AF. This would allow prophylactic treatment to be administered, potentially preventing AF. However, ECG signals acquired by wearable sensors are susceptible to artefact, making it difficult to distinguish between physiological changes in P-wave morphology, and changes due to noise. The aim of this study was to design and assess the performance of a novel automated P-wave quality assessment tool to identify high-quality P-waves, for AF prediction. We designed a two-stage algorithm which uses P-wave template-matching to assess quality. Its performance was assessed using the AFPDB, a database of wearable sensor ECG signals acquired from both healthy subjects and patients susceptible to AF. The algorithm’s quality assessments of 97,989 P-waves were compared to manual annotations. The algorithm identified high-quality P-waves with high sensitivity (93%) and good specificity (82%), indicating that it may have utility for identifying high-quality P-waves in wearable sensor data. Measurements of P-wave morphology derived from high-quality P-waves could be used to predict AF, improving patient outcomes, and reducing healthcare costs. Further studies assessing the clinical utility of the presented tool are warranted for validation.


2018 ◽  
Vol 89 (11) ◽  
pp. 2098-2112 ◽  
Author(s):  
Xueliang Xiao ◽  
Ke Dong ◽  
Chenhao Li ◽  
Guanzheng Wu ◽  
Hongtao Zhou ◽  
...  

Long-term electrocardiogram (ECG) recording can reveal some vital cardiovascular disorders and provide warning of human sudden cerebral or vascular diseases in advance. This requires high-quality ECG skin electrodes. Gel (Ag/AgCl) electrodes were reported to have good signal quality in ECG acquisition, but easily caused human skin irritation or allergy. Consequently, textile electrodes have attracted more attention for long-term ECG acquisition. In this paper, eight woven fabrics with diverse yarns and weft densities were fabricated in plain and honeycomb structures. The fabrics were investigated in terms of comfortability, fabric–skin contact impedance and acquired bio-signal quality. Honeycomb weave electrodes were measured with a high comfort level from subjective and objective views, including pleasant tactile comfort, high visual acceptance, good air permeability and good heat transfer. Weave electrodes made of all conductive filaments in high density had low skin contact impedance and high-quality ECG signals. An increase of compression load on weave electrodes resulted in a decrease of contact impedance with a high signal quality. A conductive honeycomb weave with unit repeat of 6*6 warps*wefts presented the highest score of acquired ECG signals of all studied electrodes based on the qualities of the QRS complex, P and T waves, R peak amplitude and variation and signal-to-noise ratio. This study contributes to the future design and fabrication of textile electrodes using honeycomb weave in long-term and real-time collection of human ECGs.


2016 ◽  
Vol 49 (6) ◽  
pp. 2106-2115 ◽  
Author(s):  
Janusz Wolny ◽  
Ireneusz Buganski ◽  
Pawel Kuczera ◽  
Radoslaw Strzalka

A very serious concern of scientists dealing with crystal structure refinement, including theoretical research, pertains to the characteristic bias in calculatedversusmeasured diffraction intensities, observed particularly in the weak reflection regime. This bias is here attributed to corrective factors for phonons and, even more distinctly, phasons, and credible proof supporting this assumption is given. The lack of a consistent theory of phasons in quasicrystals significantly contributes to this characteristic bias. It is shown that the most commonly used exponential Debye–Waller factor for phasons fails in the case of quasicrystals, and a novel method of calculating the correction factor within a statistical approach is proposed. The results obtained for model quasiperiodic systems show that phasonic perturbations can be successfully described and refinement fits of high quality are achievable. The standard Debye–Waller factor for phonons works equally well for periodic and quasiperiodic crystals, and it is only in the last steps of a refinement that different correction functions need to be applied to improve the fit quality.


2018 ◽  
Author(s):  
Huilong Du ◽  
Chengzhi Liang

AbstractDue to the large number of repetitive sequences in complex eukaryotic genomes, fragmented and incompletely assembled genomes lose value as reference sequences, often due to short contigs that cannot be anchored or mispositioned onto chromosomes. Here we report a novel method Highly Efficient Repeat Assembly (HERA), which includes a new concept called a connection graph as well as algorithms for constructing the graph. HERA resolves repeats at high efficiency with single-molecule sequencing data, and enables the assembly of chromosome-scale contigs by further integrating genome maps and Hi-C data. We tested HERA with the genomes of rice R498, maize B73, human HX1 and Tartary buckwheat Pinku1. HERA can correctly assemble most of the tandemly repetitive sequences in rice using single-molecule sequencing data only. Using the same maize and human sequencing data published by Jiao et al. (2017) and Shi et al. (2016), respectively, we dramatically improved on the sequence contiguity compared with the published assemblies, increasing the contig N50 from 1.3 Mb to 61.2 Mb in maize B73 assembly and from 8.3 Mb to 54.4 Mb in human HX1 assembly with HERA. We provided a high-quality maize reference genome with 96.9% of the gaps filled (only 76 gaps left) and several incorrectly positioned sequences fixed compared with the B73 RefGen_v4 assembly. Comparisons between the HERA assembly of HX1 and the human GRCh38 reference genome showed that many gaps in GRCh38 could be filled, and that GRCh38 contained some potential errors that could be fixed. We assembled the Pinku1 genome into 12 scaffolds with a contig N50 size of 27.85 Mb. HERA serves as a new genome assembly/phasing method to generate high quality sequences for complex genomes and as a curation tool to improve the contiguity and completeness of existing reference genomes, including the correction of assembly errors in repetitive regions.


2022 ◽  
Author(s):  
Hao Chu ◽  
Chenxi Yang ◽  
Yantao Xing ◽  
Jianqing Li ◽  
Chengyu Liu

Abstract PurposeLong-term electrocardiogram (ECG) monitoring is an essential approach for the early diagnosis of cardiovascular diseases. Flexible dry electrodes that contains electrolyte without water could be a potential substitution of wet electrodes for long-term ECG monitoring. Therefore, this paper developes a long-term, portable ECG patch based on flexible dry electrodes, namely SEUECG-100.MethodA device consists of analog-front-end acquisition, data acquisition, and storage modules is developed and tested. An impedance test was conducted to compare the skin-electrode impedance of the flexible dry electrode and the Ag/AgCl wet electrode. The ECG signals were simutanously collected from the same subject using the SEUECG-100 and Shimmer device , which were then compared and analyzed from the perspective of ECG morphology, RR interval, and signal quality indices (SQI).ResultsThe experimental results reveal that the flexible dry electrode has the characteristics of low skin-electrode impedance. SEUECG-100 could collect high-quality ECG signals. The ECG signals collected by the two devices have a high RR interval correlation (r=0.999). SQI results show that SEUECG-100 is better than the Shimmer device in overcoming baseline drift. Long-term ECG acquisition and storage experiments show that SEUECG-100 could collect ECG signals with good stability and high reliability.ConclusionThe implementation of the proposed system design with dry electrodes could can effectively record long-term ECG monitoring with high quality in comparison to systems with wet electrodes from both impedance characteristics and signal morphology aspects.


2017 ◽  
Vol 17 (08) ◽  
pp. 1750111 ◽  
Author(s):  
M. M. BENOSMAN ◽  
F. BEREKSI-REGUIG ◽  
E. GORAN SALERUD

Heart rate variability (HRV) analysis is used as a marker of autonomic nervous system activity which may be related to mental and/or physical activity. HRV features can be extracted by detecting QRS complexes from an electrocardiogram (ECG) signal. The difficulties in QRS complex detection are due to the artifacts and noises that may appear in the ECG signal when subjects are performing their daily life activities such as exercise, posture changes, climbing stairs, walking, running, etc. This study describes a strong computation method for real-time QRS complex detection. The detection is improved by the prediction of the position of [Formula: see text] waves by the estimation of the RR intervals lengths. The estimation is done by computing the intensity of the electromyogram noises that appear in the ECG signals and known here in this paper as ECG Trunk Muscles Signals Amplitude (ECG-TMSA). The heart rate (HR) and ECG-TMSA increases with the movement of the subject. We use this property to estimate the lengths of the RR intervals. The method was tested using famous databases, and also with signals acquired when an experiment with 17 subjects from our laboratory. The obtained results using ECG signals from the MIT-Noise Stress Test Database show a QRS complex detection error rate (ER) of 9.06%, a sensitivity of 95.18% and a positive prediction of 95.23%. This method was also tested against MIT-BIH Arrhythmia Database, the result are 99.68% of sensitivity and 99.89% of positive predictivity, with ER of 0.40%. When applied to the signals obtained from the 17 subjects, the algorithm gave an interesting result of 0.00025% as ER, 99.97% as sensitivity and 99.99% as positive predictivity.


Sign in / Sign up

Export Citation Format

Share Document