Acne is a general but somber skin disease, which affects approximately 80% adolescents and young adults in 11–30 age groups. 42.5 % of men and 50.9 % of women keep onto suffer from this disease into their twenties. Bacterial resistance is now at the alarming stage due to the irrational use of antibiotics. Hence, search for new lead molecule/bioactive and rational delivery of the existing drug (for better therapeutic effect) to the site of action is the need of the hour. Plants and plant-derived products have been an integral part of health care system since time immemorial. Therefore, plants that are currently used for the treatment of acne and those with a high potential are summarized in the present review. Most active plant extracts, namely, P. granatum, M. alba, A. anomala, and M. aquifolium exhibit minimum inhibitory concentration (MIC) in the range of 4–50 µg/mL against P. acnes, while aromatic oils of C. obovoides, C. natsudaidai, C. japonica, and C. nardus possess MICs 0.005–0.6 ?L/mL and phytomolecules such as rhodomyrtone, pulsaquinone, hydropulsaquinone, honokiol, magnolol, xanthohumollupulones, chebulagic acid and rhinacanthin-C show MIC in the range of 0.5–12.5 ?g/mL. Novel drug delivery tant plant leads in the treatment of acne have also been discussed.
REVIEW ON ANTIMICROBIAL AND ANTI ACNE POTENTIAL OF KAEMPFERIA SPP.
