Metabolic Changes in Long-Term Stimulated Fast Muscles

Author(s):  
M. Brown ◽  
M. Cotter ◽  
O. Hudlická ◽  
M. Smith ◽  
G. Vrbová
2018 ◽  
Vol 9 ◽  
Author(s):  
Martina Rojnic Kuzman ◽  
Dina Bosnjak Kuharic ◽  
Ivana Kekin ◽  
Porin Makaric ◽  
Zoran Madzarac ◽  
...  

2014 ◽  
Vol 27 (3) ◽  
pp. 379-389 ◽  
Author(s):  
F. Molinari ◽  
V. Simonetti ◽  
M. Franzini ◽  
S. Pandolfi ◽  
F. Vaiano ◽  
...  

Author(s):  
Max LENZ ◽  
Robert SCHÖNBAUER ◽  
Stefan STOJKOVIC ◽  
Michael LICHTENAUER ◽  
Vera PAAR ◽  
...  

Planta ◽  
1983 ◽  
Vol 159 (2) ◽  
pp. 182-188 ◽  
Author(s):  
Andrew D. Powell ◽  
David W. M. Leung ◽  
J. Derek Bewley

2012 ◽  
Vol 8 (6) ◽  
pp. 1050-1054 ◽  
Author(s):  
H. Colinet ◽  
D. Renault

Immobilization of insects is necessary for various experimental purposes, and CO 2 exposure remains the most popular anaesthetic method in entomological research. A number of negative side effects of CO 2 anaesthesia have been reported, but CO 2 probably brings about metabolic modifications that are poorly known. In this work, we used GC/MS-based metabolic fingerprinting to assess the effect of CO 2 anaesthesia in Drosophila melanogaster adults. We analysed metabolic variation of flies submitted to acute CO 2 exposure and assessed the temporal metabolic changes during short- and long-term recovery. We found that D. melanogaster metabotypes were significantly affected by the anaesthetic treatment. Metabolic changes caused by acute CO 2 exposure were still manifested after 14 h of recovery. However, we found no evidence of metabolic alterations when a long recovery period was allowed (more than 24 h). This study points to some metabolic pathways altered during CO 2 anaesthesia (e.g. energetic metabolism). Evidence of short-term metabolic changes indicates that CO 2 anaesthesia should be used with utmost caution in physiological studies when a short recovery is allowed. In spite of this, CO 2 treatment seems to be an acceptable anaesthetic method provided that a long recovery period is allowed (more than 24 h).


1987 ◽  
Vol 65 (11) ◽  
pp. 2188-2190 ◽  
Author(s):  
C. N. Fong ◽  
H. L. Atwood ◽  
K. N. Jeejeebhoy ◽  
M. P. Charlton

The effects of malnutrition on intracellular K+ activity, (aK)i, and membrane potential, Em, were measured by means of double-barrelled K+ -selective microlectrodes in the soleus and gastrocnemius muscles of the rat. (aK)i and Em were measured in vivo in normal anaesthetized animals and in rats subjected to one of two diet restrictions: a 2-day fast or a long-term hypocaloric diet. In the soleus muscle, (aK)i fell by similar amounts in both 2-day fasted and long-term hypocalorically fed rats, while Em depolarized significantly only in hypocalorically fed rats. In the gastrocnemius muscle, neither the 2-day fast nor the hypocaloric diet affected (aK)i or Em. It is suggested that the selective loss of K+ from the soleus muscle may be related to its activity pattern.


2019 ◽  
Vol 18 (2) ◽  
pp. 114-119
Author(s):  
A. B. Smirnova ◽  
B. S. Pershin ◽  
N. V. Myakova

Modern technologies of treatment of children with oncohaematological diseases allowed to noticebly increase the survival indexes in this group of patients, enhancing the value of maintenance of their life quality. More than half of those who received long-term steriod and radiation treatment develop cataract that causes decrease in vision. In this review we represent data concerning mechanisms of cataract formation in patients after steriod and radiation treatment, results of anatomical, physiological and biochemical studies of the lens as well as metabolic changes in aqueous humor leading to cataract formation.


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