Effects of Ageing upon Airways Smooth Muscle Contractility

1994 ◽  
pp. 185-218 ◽  
Author(s):  
Marsha Wills-Karp
Keyword(s):  
Smooth Muscle ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility ◽  
Airways Smooth Muscle

The Role of Biaxial Loading on Smooth Muscle Contractility in the Nulliparous Murine Cervix

2021 ◽  
Author(s):  
Cassandra K. Conway ◽  
Asha Varghese ◽  
Mala Mahendroo ◽  
Kristin S. Miller
Keyword(s):  
Smooth Muscle ◽  
Biaxial Loading ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility

Extracellular Matrix Rigidity Modulates Human Cervical Smooth Muscle Contractility—New Insights into Premature Cervical Failure and Spontaneous Preterm Birth

2020 ◽  
Vol 28 (1) ◽  
pp. 237-251 ◽  
Author(s):  
Joy Vink ◽  
Victoria Yu ◽  
Sudip Dahal ◽  
James Lohner ◽  
Conrad Stern-Asher ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Smooth Muscle ◽  
Preterm Birth ◽  
Matrix Rigidity ◽  
Spontaneous Preterm Birth ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility

scholarly journals Complementary vasoactivity and matrix remodelling in arterial adaptations to altered flow and pressure

2008 ◽  
Vol 6 (32) ◽  
pp. 293-306 ◽  
Author(s):  
A Valentín ◽  
L Cardamone ◽  
S Baek ◽  
J.D Humphrey
Keyword(s):  
Smooth Muscle ◽  
Continuum Theory ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility ◽  
Rates Of Change ◽  
Biomechanical Loading ◽  
Smooth Muscle Proliferation ◽  
And Function ◽  
Diverse Data ◽  
Induced Changes

Arteries exhibit a remarkable ability to adapt to sustained alterations in biomechanical loading, probably via mechanisms that are similarly involved in many arterial pathologies and responses to treatment. Of particular note, diverse data suggest that cell and matrix turnover within vasoaltered states enables arteries to adapt to sustained changes in blood flow and pressure. The goal herein is to show explicitly how altered smooth muscle contractility and matrix growth and remodelling work together to adapt the geometry, structure, stiffness and function of a representative basilar artery. Towards this end, we employ a continuum theory of constrained mixtures to model evolving changes in the wall, which depend on both wall shear stress-induced changes in vasoactive molecules (which alter smooth muscle proliferation and synthesis of matrix) and intramural stress-induced changes in growth factors (which alter cell and matrix turnover). Simulations show, for example, that such considerations help explain the different rates of experimentally observed adaptations to increased versus decreased flows as well as differences in rates of change in response to increased flows or pressures.

scholarly journals Are Interstitial Cells of Cajal Involved in Mechanical Stress-Induced Gene Expression and Impairment of Smooth Muscle Contractility in Bowel Obstruction?

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e76222 ◽  
Author(s):  
Chester C. Wu ◽  
You-Min Lin ◽  
Jerry Gao ◽  
John H. Winston ◽  
Leo K. Cheng ◽  
...  
Keyword(s):  
Gene Expression ◽  
Smooth Muscle ◽  
Mechanical Stress ◽  
Bowel Obstruction ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility ◽  
Cells Of Cajal
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