Biomarkers for Individualized Oral Cancer Therapy

2015 ◽  
pp. 43-60
Author(s):  
Nisha J. D’Silva
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer

scholarly journals Use of the ONCO-TreC electronic diary compared with a standard paper diary to improve adherence to oral cancer therapy in patients with solid and haematological tumours: protocol for a randomised controlled trial

BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e055814
Author(s):  
Alessandro Passardi ◽  
Patrizia Serra ◽  
Orazio Caffo ◽  
Carla Masini ◽  
Erika Brugugnoli ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Cancer Therapy ◽  
Oral Cancer ◽  
Healthcare Professionals ◽  
Controlled Trial ◽  
Dropout Rate ◽  
Electronic Diary ◽  
Paper Diary ◽  
Standard Paper ◽  
Randomised Controlled

IntroductionONCO-TreC platform consists of a mobile application delivered to patients as electronic diary and a web-based dashboard managed by healthcare professionals. We aim to compare the effectiveness of ONCO-TreC electronic diary with a standard paper diary, in improving adherence to oral cancer therapy in patients with solid and haematological tumours.Methods and analysisThis is an open label, superiority, randomised controlled trial conducted in two Italian oncology units. Patients will be randomised with a 1:1 ratio to electronic or paper diary. For both groups a counsellor will be responsible for drug and diary delivery. The evaluation period will end after six cycles of therapy. The primary aim is to compare the proportion of non-adherent patients in the two arms. Adherence will be measured through pill count; anyone who takes less than 90% of the total prescribed drug dose will be considered non-adherent. Assuming a percentage of non-adherent patients to oral therapy of 40% in arm B, and a 60% reduction in this percentage in arm A, a sample of 124 patients will provide 80% power to identify an absolute difference greater than 24 percentage points using a bilateral Fisher’s exact test with a significance level of 0.05. Considering a dropout rate of 10%, approximately 136 patients will have to be enrolled. The primary analysis will be performed on the intention-to-treat population. Secondary aims are to describe the reasons for non-adherence, the level of satisfaction of patients and healthcare professionals with the paper and electronic diary, and the impact of non-adherence in terms of healthcare costs.Ethics and disseminationEthical approval was obtained from Romagna Ethics Committee (CEROM), study ID 2108, prot. n. IRST 100.28 of 10/04/2020. Informed consent will be obtained from all study participants. Findings will be disseminated through peer-reviewed journals, conferences and event presentations.Protocol versionVersion 2, 6 April 2021.Trial registration numberNCT04826458.

Immobilization of the mandible in oral cancer therapy

1979 ◽  
Vol 138 (4) ◽  
pp. 508-511 ◽  
Author(s):  
Zelig H. Lieberman ◽  
D.Lamar Byrd ◽  
Tommy J. Davidson
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer

Angelica gigas Nakai extract-loaded fast-dissolving nanofiber based on poly(vinyl alcohol) and Soluplus for oral cancer therapy

2017 ◽  
Vol 526 (1-2) ◽  
pp. 225-234 ◽  
Author(s):  
Suyeong Nam ◽  
Jeong-Jun Lee ◽  
Song Yi Lee ◽  
Jae Young Jeong ◽  
Wie-Soo Kang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Angelica Gigas ◽  
Angelica Gigas Nakai

A case of therapy-related myelodysplastic syndrome after oral cancer therapy

Toukeibu Gan ◽  
2017 ◽  
Vol 43 (3) ◽  
pp. 388-392
Author(s):  
Mioko Matsuo ◽  
Rina Jiromaru
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Myelodysplastic Syndrome

A Case of Drug Hepatopathy which was Suspected of HBV Reactivation during Oral Cancer Therapy

2014 ◽  
Vol 27 (1) ◽  
pp. 56-60
Author(s):  
TADAHIKO YANAGITA ◽  
SHUNGO FURUDOI ◽  
YOSHIKI ISHIDA ◽  
TAKAHIDE KOMORI
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Hbv Reactivation

Incidence of oral cancer therapy medication errors at a private university hospital: Rationale for oral cancer therapy specific policies and procedures

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 6624-6624
Author(s):  
S. D. Stelts ◽  
C. C. Nesheiwat ◽  
J. Ashley ◽  
T. McKibbin ◽  
R. Jennifer ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Medication Errors ◽  
Private University ◽  
University Hospital ◽  
Policies And Procedures

PS-044 Food and drug interactions in oral cancer therapy: Abstract PS-044 Table 1

2016 ◽  
Vol 23 (Suppl 1) ◽  
pp. A233.1-A233
Author(s):  
T Gramage Caro ◽  
E Delgado Silveira ◽  
N Vicente Oliveros ◽  
MI Muñoz Ojeda ◽  
T Bermejo Vicedo
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Drug Interactions

Adherence to oral cancer therapy in older adults: The International Society of Geriatric Oncology (SIOG) taskforce recommendations

2017 ◽  
Vol 57 ◽  
pp. 58-66 ◽  
Author(s):  
Anna Rachelle Mislang ◽  
Tanya M. Wildes ◽  
Ravindran Kanesvaran ◽  
Capucine Baldini ◽  
Holly M. Holmes ◽  
...  
Keyword(s):  
Older Adults ◽  
Cancer Therapy ◽  
Oral Cancer ◽  
International Society ◽  
Geriatric Oncology

scholarly journals Anticancer activity of pyrithione zinc in oral cancer cells identified in small molecule screens and xenograft model: Implications for oral cancer therapy

2015 ◽  
Vol 9 (8) ◽  
pp. 1720-1735 ◽  
Author(s):  
Gunjan Srivastava ◽  
Ajay Matta ◽  
Guodong Fu ◽  
Raj Thani Somasundaram ◽  
Alessandro Datti ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Oral Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Small Molecule ◽  
Xenograft Model ◽  
Oral Cancer Cells
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