geriatric oncology
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2022 ◽  
Vol 29 ◽  
pp. 28-35
Author(s):  
Dong Xue ◽  
Pingping Li ◽  
Tsun Hsuan Chen ◽  
Qiuling Shi ◽  
Xin Shelley Wang

Cancers ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 244
Author(s):  
Claudia Martinez-Tapia ◽  
Marie Laurent ◽  
Elena Paillaud ◽  
Philippe Caillet ◽  
Emilie Ferrat ◽  
...  

Screening tools have been developed to identify patients warranting a complete geriatric assessment (GA). However, GA lacks standardization and does not capture important aspects of geriatric oncology practice. We measured and compared the diagnostic performance of screening tools G8 and modified G8 according to multiple clinically relevant reference standards. We included 1136 cancer patients ≥ 70 years old referred for GA (ELCAPA cohort; median age, 80 years; males, 52%; main locations: digestive (36.3%), breast (16%), and urinary tract (14.8%); metastases, 43.5%). Area under the receiver operating characteristic curve (AUROC) estimates were compared between both tools against: (1) the detection of ≥1 or (2) ≥2 GA impairments, (3) the prescription of ≥1 geriatric intervention and the identification of an unfit profile according to (4) a latent class typology, expert-based classifications from (5) Balducci, (6) the International Society of Geriatric Oncology task force (SIOG), or using (7) a GA frailty index according to the Rockwood accumulation of deficits principle. AUROC values were ≥0.80 for both tools under all tested definitions. They were statistically significantly higher for the modified G8 for six reference standards: ≥1 GA impairment (0.93 vs. 0.89), ≥2 GA impairments (0.90 vs. 0.87), ≥1 geriatric intervention (0.85 vs. 0.81), unfit according to Balducci (0.86 vs. 0.80) and SIOG classifications (0.88 vs. 0.83), and according to the GA frailty index (0.86 vs. 0.84). Our findings demonstrate the robustness of both screening tools against different reference standards, with evidence of better diagnostic performance of the modified G8.


2021 ◽  
Vol 12 (8) ◽  
pp. S55
Author(s):  
T. Hoang ◽  
N. Timilshina ◽  
R. Jin ◽  
S. Monginot ◽  
S. Alibhai

2021 ◽  
Vol 12 (8) ◽  
pp. S67
Author(s):  
T. Mizutani ◽  
K.L. Cheung ◽  
Y. Hakobyan ◽  
H. Lane ◽  
L. Decoster ◽  
...  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 298-299
Author(s):  
Jessica Krok-Schoen

Abstract Despite the majority of cancer survivors being older adults, the connection between oncology, geriatrics, and gerontology remains unexplored. Our symposium will provide insights across the cancer continuum from prevention through survivorship as well as a comprehensive view of the connection between gerontological and geriatric factors in oncology. Specifically, we will discuss the biopsychosocial and behavioral factors among older adults with cancer, their effect on health outcomes, and how researchers and clinicians can intervene to improve health outcomes. The first abstract by Dr. Cadet found that despite a lack of knowledge of options and harms of cancer screening among older adults with low health literacy, there was a desire to understand more to better their health. The second abstract by Dr. Bhattacharyya found that older patients with cancer experience high levels of social isolation, loneliness, and fear that are heightened by individual and technology-based barriers to telehealth. The third abstract by Dr. Carroll found that breast cancer survivors with good sleep quality had less accelerated biological aging than those with sleep problems. The fourth abstract by Dr. Krok-Schoen utilized one of the largest datasets of older women, the Women’s Health Initiative, and found multiple gerontological and geriatric factors associated with physical activity among older female cancer survivors. Closing this symposium is Dr. Guida, a Program Director at the National Cancer Institute (NCI), who will profile the current research efforts, programmatic priorities, and current funding in aging and cancer. These multidisciplinary researchers and clinicians will provide a comprehensive symposium regarding geriatric oncology.


2021 ◽  
Vol 12 (8) ◽  
pp. S65
Author(s):  
R. Elias ◽  
M.K. Eanniello ◽  
K. Doney ◽  
Q. Yu ◽  
P. Kaehrle ◽  
...  

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