Prediction of Infarct Localization from Myocardial Deformation

The article deals with the physiology of the heart and methods to assess fetal cardiac function. The leadingedge technique to assess the myocardial deformation properties by speckle tracking echocardiography in prenatal period is presented.

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Assessment of right ventricular free wall longitudinal myocardial deformation using speckle tracking imaging in normal subjects

Journal of Huazhong University of Science and Technology [Medical Sciences] ◽

10.1007/s11596-008-0220-8 ◽

2008 ◽

Vol 28 (2) ◽

pp. 194-196 ◽

Cited By ~ 10

Author(s):

Chun Tong ◽

Chunlei Li ◽

Jialin Song ◽

Hongyun Liu ◽

Youbin Deng

Keyword(s):

Right Ventricular ◽

Speckle Tracking ◽

Normal Subjects ◽

Myocardial Deformation ◽

Ventricular Free Wall ◽

Free Wall ◽

Speckle Tracking Imaging ◽

Right Ventricular Free Wall

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Assessment of myocardial deformation with CMR: a comparison with ultrasound speckle tracking in a cohort of highly trained endurance athletes

European Heart Journal - Cardiovascular Imaging ◽

10.1093/ehjci/jeaa356.272 ◽

2021 ◽

Vol 22 (Supplement_1) ◽

Author(s):

B Domenech-Ximenos ◽

M Sanz-De La Garza ◽

A Sepulveda-Martinez ◽

D Lorenzatti ◽

F Simard ◽

...

Keyword(s):

Speckle Tracking ◽

Longitudinal Strain ◽

Systolic Function ◽

Global Longitudinal Strain ◽

Myocardial Deformation ◽

Endurance Athletes ◽

National Budget ◽

Complex Anatomy ◽

Exercise Induced ◽

Public Grant

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Plan Nacional I.D., Del Programa Estatal de Fomento De La Investigación Científica y Técnica de Excelencia, Subprograma De Generación Del Conocimiento, Ministerio de Economía y Competitividad 2013. Background Myocardial deformation integrated with cardiac dimensions provides a comprehensive assessment of the ventricular remodelling patterns induced by cumulative effects of intensive exercise. Feature tracking(FT) can measure myocardial deformation from cardiac magnetic resonance(CMR) cine sequences; however, its accuracy is still scarcely validated. Purpose Our aim was to compare FT’s accuracy and reproducibility to speckle tracking echocardiography (STE) in highly trained endurance athletes (EAs). Methods 93 EAs (>12 hours training/week during the last 5 years, 52% male, 35 ± 5.1 years) and 72 age-matched controls underwent a resting CMR and a transthoracic echocardiography to assess biventricular exercise-induced remodelling and biventricular global longitudinal strain (GLS) by CMR-FT and STE. Results High endurance training load was associated with larger bi-ventricular and bi-atrial sizes and mildly reduced systolic function of both ventricles (p < 0,05). Strain values (both by CMR-FT and STE) proportionally decreased with increasing ventricular volumes potentially depicting the increased volume and functional biventricular reserve that characterize EAs heart. Strain values were lower when assessed by CMR-FT as compared to STE (p < 0.001), with good reproducibility for the LV (bias = 3.94%, LOA= ± 4.27%) but wider variability for RV strains (Figure 2). Conclusions Biventricular longitudinal strain values were lower when assessed by FT compared to STE. Both methods were comparable when measuring LV strain but not RV strain. These differences might be justified by FT’s lower in-plane spatial and temporal resolution, which is particularly relevant for the complex anatomy of the RV. Abstract Figure. Fig 1. Bland-Altman plots; FT vs STE.

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Myocardial Deformation in Fontan Patients Assessed by Cardiac Magnetic Resonance Feature Tracking: Correlation with Function, Clinical Course, and Biomarkers

Pediatric Cardiology ◽

10.1007/s00246-021-02650-w ◽

2021 ◽

Author(s):

Alessia Callegari ◽

Simona Marcora ◽

Barbara Burkhardt ◽

Michael Voutat ◽

Christian Johannes Kellenberger ◽

...

Keyword(s):

Ventricular Function ◽

Feature Tracking ◽

Heart Diseases ◽

Fontan Operation ◽

Myocardial Deformation ◽

Time Interval ◽

Ventricular Volumes ◽

Atrioventricular Valve Regurgitation ◽

Cine Mr ◽

Fontan Patients

AbstractCardiac MR (CMR) is a standard modality for assessing ventricular function of single ventricles. CMR feature-tracking (CMR-FT) is a novel application enabling strain measurement on cine MR images and is used in patients with congenital heart diseases. We sought to assess the feasibility of CMR-FT in Fontan patients and analyze the correlation between CMR-FT strain values and conventional CMR volumetric parameters, clinical findings, and biomarkers. Global circumferential (GCS) and longitudinal (GLS) strain were retrospectively measured by CMR-FT on Steady-State Free Precession cine images. Data regarding post-operative course at Fontan operation, and medication, exercise capacity, invasive hemodynamics, and blood biomarkers at a time interval ± 6 months from CMR were collected. Forty-seven patients underwent CMR 11 ± 6 years after the Fontan operation; age at CMR was 15 ± 7 years. End-diastolic volume (EDV) of the SV was 93 ± 37 ml/m2, end-systolic volume (ESV) was 46 ± 23 ml/m2, and ejection fraction (EF) was 51 ± 11%. Twenty (42%) patients had a single right ventricle (SRV). In single left ventricle (SLV), GCS was higher (p < 0.001), but GLS was lower (p = 0.04) than in SRV. GCS correlated positively with EDV (p = 0.005), ESV (p < 0.001), and EF (p ≤ 0.0001). GLS correlated positively with EF (p = 0.002), but not with ventricular volumes. Impaired GCS correlated with decreased ventricular function (p = 0.03) and atrioventricular valve regurgitation (p = 0.04) at echocardiography, direct atriopulmonary connection (p = 0.02), post-operative complications (p = 0.05), and presence of a rudimentary ventricle (p = 0.01). A reduced GCS was associated with increased NT-pro-BNP (p = 0.05). Myocardial deformation can be measured by CMR-FT in Fontan patients. SLVs have higher GCS, but lower GLS than SRVs. GCS correlates with ventricular volumes and EF, whereas GLS correlates with EF only. Myocardial deformation shows a relationship with several clinical parameters and NT-pro-BNP.

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