Predictive Tools for Older Cancer Patient Management

2019 ◽  
pp. 1-15
Author(s):  
Ki Hyang Kim ◽  
Martine Extermann
2017 ◽  
Vol 44 (13) ◽  
pp. 2153-2157
Author(s):  
Carl von Gall ◽  
Piotr Maniawski ◽  
Fred Verzijlbergen ◽  
Ignasi Carrio ◽  
Thomas Beyer ◽  
...  

Author(s):  
Ken Chen ◽  
Funda Meric-Bernstam ◽  
Hao Zhao ◽  
Tenghui Chen ◽  
Kenna Shaw ◽  
...  

2018 ◽  
Vol 10 (431) ◽  
pp. eaan8840 ◽  
Author(s):  
Xilin Sun ◽  
Zunyu Xiao ◽  
Gongyan Chen ◽  
Zhaoguo Han ◽  
Yang Liu ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1632 ◽  
Author(s):  
Anthony Genna ◽  
Aline M. Vanwynsberghe ◽  
Amélie V. Villard ◽  
Charles Pottier ◽  
Julien Ancel ◽  
...  

Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced ability to adapt to diverse microenvironments encountered during the metastatic spread. Accordingly, EMTs play a crucial role in the biology of circulating tumor cells (CTCs) and contribute to their heterogeneity. Here, we review major EMT-driven properties that may help hybrid Epithelial/Mesenchymal CTCs to survive in the bloodstream and accomplish early phases of metastatic colonization. We then discuss how interrogating EMT in CTCs as a companion biomarker could help refine cancer patient management, further supporting the relevance of CTCs in personalized medicine.


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