Helminth Electron Transport Inhibitors Produced by Fungi

2018 ◽  
pp. 297-329 ◽  
Author(s):  
Mihoko Mori ◽  
Kenichi Nonaka ◽  
Rokuro Masuma ◽  
Satoshi Ōmura ◽  
Kazuro Shiomi
Keyword(s):  
Electron Transport ◽  
Transport Inhibitors

Effects of Diphenylether Herbicides on Reactions of Mitochondria and Chloroplasts

Weed Science ◽  
1970 ◽  
Vol 18 (5) ◽  
pp. 636-642 ◽  
Author(s):  
D. E. Moreland ◽  
W. J. Blackmon ◽  
H. G. Todd ◽  
F. S. Farmer
Keyword(s):  
Electron Transport ◽  
Oxygen Uptake ◽  
Spinacia Oleracea ◽  
White Potato ◽  
Light Reaction ◽  
Site Of Action ◽  
Transport Inhibitors ◽  
Atp Generation ◽  
A Site ◽  
Limited Oxygen

Effects of three diphenylether herbicides [2,4-dichlorophenyl-p-nitrophenyl ether (nitrofen); 2,4,6-trichlorophenyl-4′-nitrophenyl ether (hereinafter referred to as MC-1478); and 2,4′-dinitro-4-trifluoromethyl-diphenylether (hereinafter referred to as C-6989)] were measured on phosphorylation and electron transport in spinach(Spinacia oleraceaL.) chloroplasts, and mung bean(Phaseolus aureusL., var. Jumbo) and white potato tuber(Solarium tuberosumL.) mitochondria. All of the diphenylethers acted primarily as inhibitors of chloroplast noncyclic electron transport, and the coupled photophosphorylation. The compounds ranked in the following decreasing order of inhibitory effectiveness: MC-1478 ≥ C-6989 >> nitrofen. A site of action close to light reaction II was suggested. At high molar concentrations, marginal interference with cyclic electron transport or phosphorylation was obtained. In mitochondria, MC-1478 and nitrofen acted primarily as electron transport inhibitors with malate, NADH, and succinate as substrates. MC-1478 was a slightly stronger inhibitor than nitrofen. Only slight stimulation of ADP-limited oxygen uptake was obtained during the oxidation of NADH and succinate; whereas, strong inhibition of oxygen uptake was obtained with malate. C-6989 also weakly stimulated ADP-limited oxygen uptake with NADH and succinate but differed from the two chlorinated diphenylethers in that electron transport was not inhibited when ADP was present in excess. Interference with ATP generation could be one of the mechanisms through which the phytotoxicity of diphenylether herbicides is expressed.

Electron transport pathways for the oxidation of endogenous substrate(s) in Acidithiobacillus ferrooxidans

2006 ◽  
Vol 52 (4) ◽  
pp. 317-327 ◽  
Author(s):  
Yongqiang Chen ◽  
Isamu Suzuki
Keyword(s):  
Electron Transport ◽  
Electron Acceptor ◽  
Acidithiobacillus Ferrooxidans ◽  
Complex I ◽  
Iron Chelators ◽  
Endogenous Respiration ◽  
Sugar Alcohols ◽  
Transport Pathways ◽  
Endogenous Substrate ◽  
Transport Inhibitors

Oxidation of endogenous substrate(s) of Acidithiobacillus ferrooxidans with O2 or Fe3+ as electron acceptor was studied in the presence of uncouplers and electron transport inhibitors. Endogenous substrate was oxidized with a respiratory quotient (CO2 produced/O2 consumed) of 1.0, indicating its carbohydrate nature. The oxidation was inhibited by complex I inhibitors (rotenone, amytal, and piericidin A) only partially, but piericidin A inhibited the oxidation with Fe3+ nearly completely. The oxidation was stimulated by uncouplers, and the stimulated activity was more sensitive to inhibition by complex I inhibitors. HQNO (2-heptyl-4-hydroxyquinoline N-oxide) also stimulated the oxidation, and the stimulated respiration was more sensitive to KCN inhibition than uncoupler stimulated respiration. Fructose, among 20 sugars and sugar alcohols including glucose and mannose, was oxidized with a CO2/O2 ratio of 1.0 by the organism. Iron chelators in general stimulated endogenous respiration, but some of them reduced Fe3+ chemically, introducing complications. The results are discussed in view of a branched electron transport system of the organism and its possible control.Key words: Acidithiobacillus ferrooxidans, endogenous respiration, uncouplers, electron transport.

The discovery of 3-(1-aminoethylidene)quinoline-2, 4(1H,3H)-dione derivatives as novel PSII electron transport inhibitors

2013 ◽  
Vol 17 (4) ◽  
pp. 701-710 ◽  
Author(s):  
Yu-Xiu Liu ◽  
Hua-Ping Zhao ◽  
Zi-Wen Wang ◽  
Yong-Hong Li ◽  
Hai-Bin Song ◽  
...  
Keyword(s):  
Electron Transport ◽  
Transport Inhibitors

Photoautotrophic Cultured Plant Cells: A Novel System to Survey New Photosynthetic Electron Transport Inhibitors

1991 ◽  
Vol 46 (7-8) ◽  
pp. 563-568 ◽  
Author(s):  
Fumihiko Sato ◽  
Yasuyuki Yamada ◽  
Sang Soo Kwak ◽  
Katsunori Ichinose ◽  
Mitsuhiro Kishida ◽  
...  
Keyword(s):  
Electron Transport ◽  
Cultured Cells ◽  
Plant Cells ◽  
Photosynthetic Electron Transport ◽  
Herbicidal Activity ◽  
Marchantia Polymorpha ◽  
Hill Reaction ◽  
Transport Inhibitors ◽  
Comparison Of The Results ◽  
The Hill

Abstract The responses of photoautotrophic (PA) cultured cells of tobacco (Nicotiana tabacum cv. Samsun NN) and liverwort (Marchantia polymorpha L.) to thirty-eight cyclohexanedione derivatives were surveyed. Each derivative was also tested for inhibitory activity on photosynthetic electron transport (PET), using isolated thylakoids, and herbicidal activity, using seed­ lings and mature plants. Comparison of the results from the different assays showed that the responses of PA cells to each com pound correlated more closely with the responses of seed­ lings and mature plants than did the results of the Hill reaction assays. Our findings suggest that PA cultured cells would be a suitable screening material for identifying potential herbicides with PET-inhibiting activity.

Inhibition of Oxygen Evolution by Cacalol and Its Derivatives

1991 ◽  
Vol 46 (9-10) ◽  
pp. 777-780 ◽  
Author(s):  
B. Lotina-Hennsen ◽  
J. L. Roque-Reséndiz ◽  
M. Jiménez ◽  
M. Aguilar
Keyword(s):  
Electron Transport ◽  
Oxygen Evolution ◽  
Photosystem I ◽  
Atp Synthesis ◽  
The Other ◽  
Other Hand ◽  
Transport Inhibitors ◽  
Proton Uptake

Abstract The inhibition of ATP synthesis, proton uptake and electron transport (basal, phosphory-lating and uncoupled) from water to methylviologen indicates that cacalol and its derivatives act as electron transport inhibitors. Since on one hand photosystem I is not affected and elec­tron transport from DPC to QA is midly affected and on the other hand the electron transport from water to DCIP, and water to silicomolibdate are inhibited, we conclude that the site of inhibition of cacalol is located at the oxygen evolution level. Cacalol derivatives inhibit elec­tron flow between P680 to QA and probably also the QB site.

Influence of Sublethal Concentrations of Herbicides and Growth Regulators on Mouseearcress (Arabidopsis thaliana) Progeny

Weed Science ◽  
1985 ◽  
Vol 33 (4) ◽  
pp. 430-434 ◽  
Author(s):  
Ron Henzell ◽  
John Phillips ◽  
Peter Diggle
Keyword(s):  
Arabidopsis Thaliana ◽  
Electron Transport ◽  
Plant Growth ◽  
Growth Regulators ◽  
Growth And Development ◽  
Auxin Transport ◽  
Photosynthetic Electron Transport ◽  
Persistent Effect ◽  
Transport Inhibitors ◽  
Sublethal Concentrations

The influence of sublethal levels of a number of herbicides and plant growth regulators on the germinability of the seeds and the growth and development of seedlings of mouseearcress [Arabidopsis thaliana(L.) Heynh. ♯ ARBTH] was determined. Only 7 of the 22 chemicals tested had a persistent effect on progeny. Amitrole (3-amino-s-triazole) was one of the most effective compounds. It caused a characteristic bleaching only in shoot tips and pods in parent plants and appeared to act directly on the progeny by accumulation in the seed. Two auxin transport inhibitors, TIBA (2,3,5-triiodobenzoic acid) and CPII (5-O-carboxyphenyl-3-phenylisoxazole), and four of the six photosynthetic electron transport inhibitors included in the study also affected progeny. They appeared to act indirectly by interfering with seed development.

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