A Novel Approach for Assessing Power Wheelchair Users’ Mobility by Using Curve Fitting

Author(s):  
Jicheng Fu ◽  
Fang Li ◽  
Marcus Ong ◽  
Tyler Cook ◽  
Gang Qian ◽  
...  

Interpolation methods and curve fitting represent so huge problem that each individual interpolation is exceptional and requires specific solutions. PNC method is such a novel tool with its all pros and cons. The user has to decide which interpolation method is the best in a single situation. The choice is yours if you have any choice. Presented method is such a new possibility for curve fitting and interpolation when specific data (for example handwritten symbol or character) starts up with no rules for polynomial interpolation. This chapter consists of two generalizations: generalization of previous MHR method with various nodes combinations and generalization of linear interpolation with different (no basic) probability distribution functions and nodes combinations. This probabilistic view is novel approach a problem of modeling and interpolation. Computer vision and pattern recognition are interested in appropriate methods of shape representation and curve modeling.


2021 ◽  
Vol 10 (2) ◽  
pp. 65
Author(s):  
Amin Gharebaghi ◽  
Mir-Abolfazl Mostafavi ◽  
Geoffrey Edwards ◽  
Patrick Fougeyrollas

Mobility is fundamental for social participation. Everyone benefits from pedestrian networks for their mobility and daily activities. People without disabilities may have little difficulty walking on narrow sidewalks, over potholes, and so on. However, people with motor disabilities (PWMD) may find it more difficult to deal with such conditions. For PWMD, even routine trips are often fraught with problems, with many different obstacles restricting their mobility and consequently rendering their participation in social and recreational activities difficult. The potential problems and risks associated with mobility for PWMD could be significantly reduced if navigation systems provided them with appropriate accessible routes. These routes should consider PWMD’s personal capabilities as well as sidewalk-network conditions. In this paper, we propose a novel approach for computing a user-specific route for PWMD. Such a route is personalized based on the user’s confidence to deal with obstacles such as slopes, uneven pavement, etc. We show how user reported confidence levels could be used to aggregate sidewalk conditions in a routing model to offer user-specific routes. The proposed methodology was developed using a fuzzy approach and is evaluated by manual wheelchair users in Quebec City.


2020 ◽  
pp. 509-538
Author(s):  
Dariusz Jacek Jakóbczak

Interpolation methods and curve fitting represent so huge problem that each individual interpolation is exceptional and requires specific solutions. Presented method is such a new possibility for curve fitting and interpolation when specific data (for example handwritten symbol or character) starts up with no rules for polynomial interpolation. The method of Probabilistic Nodes Combination (PNC) enables interpolation and modeling of two-dimensional curves using nodes combinations and different coefficients γ. This probabilistic view is novel approach a problem of modeling and interpolation. Computer vision and pattern recognition are interested in appropriate methods of shape representation and curve modeling. PNC method represents the possibilities of shape reconstruction and curve interpolation via the choice of nodes combination and probability distribution function for interpolated points. It seems to be quite new look at the problem of contour representation and curve modeling in artificial intelligence and computer vision.


2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Edward M. Giesbrecht ◽  
William C. Miller ◽  
Ian M. Mitchell ◽  
Roberta L. Woodgate

Restricted mobility is the most common impairment among older adults and a manual wheelchair is often prescribed to address these limitations. However, limited access to rehabilitation services results in older adults typically receiving little or no mobility training when they receive a wheelchair. As an alternative and novel approach, we developed a therapist-monitored wheelchair skills home training program delivered via a computer tablet. To optimize efficacy and adherence, principles of self-efficacy and adult learning theory were foundational in the program design. A participatory action design approach was used to engage older adult wheelchair users, care providers, and prescribing clinicians in an iterative design and development process. A series of prototypes were fabricated and revised, based on feedback from eight stakeholder focus groups, until a final version was ready for evaluation in a clinical trial. Stakeholder contributions affirmed and enhanced the foundational theoretical principles and provided validation of the final product for the target population.


Interpolation methods and curve fitting represent so huge problem that each individual interpolation is exceptional and requires specific solutions. Presented method is such a new possibility for curve fitting and interpolation when specific data (for example handwritten symbol or character) starts up with no rules for polynomial interpolation. The method of Probabilistic Nodes Combination (PNC) enables interpolation and modeling of two-dimensional curves using nodes combinations and different coefficients ?. This probabilistic view is novel approach a problem of modeling and interpolation. Computer vision and pattern recognition are interested in appropriate methods of shape representation and curve modeling. PNC method represents the possibilities of shape reconstruction and curve interpolation via the choice of nodes combination and probability distribution function for interpolated points. It seems to be quite new look at the problem of contour representation and curve modeling in artificial intelligence and computer vision.


Sensors ◽  
2021 ◽  
Vol 21 (24) ◽  
pp. 8275
Author(s):  
Jicheng Fu ◽  
Shuai Zhang ◽  
Hongwu Wang ◽  
Yan Daniel Zhao ◽  
Gang Qian

This study is motivated by the fact that there are currently no widely used applications available to quantitatively measure a power wheelchair user’s mobility, which is an important indicator of quality of life. To address this issue, we propose an approach that allows power wheelchair users to use their own mobile devices, e.g., a smartphone or smartwatch, to non-intrusively collect mobility data in their daily life. However, the convenience of data collection brings substantial challenges in data analysis because the data patterns associated with wheelchair maneuvers are not as strong as other activities, e.g., walking, running, etc. In addition, the built-in sensors in different mobile devices create significant heterogeneity in terms of sensitivity, noise patterns, sampling settings, etc. To address the aforementioned challenges, we developed a novel approach composed of algorithms that work collaboratively to reduce noise, identify patterns intrinsic to wheelchair maneuvers, and finalize mobility analysis by removing spikes and dips caused by abrupt maneuver changes. We conducted a series of experiments to evaluate the proposed approach. Experimental results showed that our approach could accurately determine wheelchair maneuvers regardless of the models and placements of the mobile devices.


2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.


2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687


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