scholarly journals Structural Adaptation in Normal and Cancerous Vasculature

2007 ◽  
pp. 165-178
Author(s):  
Philip K. Maini ◽  
Tomás Alarcón ◽  
Helen M. Byrne ◽  
Markus R. Owen ◽  
James Murphy
Keyword(s):  
Structural Adaptation

scholarly journals Studies of transmembrane peptides by pulse dipolar spectroscopy with semi-rigid TOPP spin labels

2021 ◽  
Author(s):  
Igor Tkach ◽  
Ulf Diederichsen ◽  
Marina Bennati
Keyword(s):  
Molecular Level ◽  
Dipolar Interaction ◽  
Spin Labels ◽  
Paramagnetic Centers ◽  
Structural Adaptation ◽  
Paramagnetic Resonance ◽  
Transmembrane Peptides ◽  
Distance Distributions ◽  
Lipid Environment ◽  
Electron Paramagnetic

AbstractElectron paramagnetic resonance (EPR)-based pulsed dipolar spectroscopy measures the dipolar interaction between paramagnetic centers that are separated by distances in the range of about 1.5–10 nm. Its application to transmembrane (TM) peptides in combination with modern spin labelling techniques provides a valuable tool to study peptide-to-lipid interactions at a molecular level, which permits access to key parameters characterizing the structural adaptation of model peptides incorporated in natural membranes. In this mini-review, we summarize our approach for distance and orientation measurements in lipid environment using novel semi-rigid TOPP [4-(3,3,5,5-tetramethyl-2,6-dioxo-4-oxylpiperazin-1-yl)-L-phenylglycine] labels specifically designed for incorporation in TM peptides. TOPP labels can report single peak distance distributions with sub-angstrom resolution, thus offering new capabilities for a variety of TM peptide investigations, such as monitoring of various helix conformations or measuring of tilt angles in membranes. Graphical Abstract

Stability of a microvessel subject to structural adaptation of diameter and wall thickness

2010 ◽  
Vol 28 (3) ◽  
pp. 271-286 ◽  
Author(s):  
I. Shafer ◽  
R. Nancollas ◽  
M. Boes ◽  
A. L. Sieminski ◽  
J. B. Geddes
Keyword(s):  
Wall Thickness ◽  
Structural Adaptation

Structural adaptations of bovine ungulates modern agrocenosis

2021 ◽  
Vol 1 (11) ◽  
pp. 6-15
Author(s):  
Sergey V. Posyabin ◽  
◽  
Elena N. Borkhunova ◽  
Vladislav V. Belogurov ◽  
Mikhail D. Kachalin ◽  
...  
Keyword(s):  
Body Size ◽  
Forest Soils ◽  
Distal Part ◽  
Static Load ◽  
High Weight ◽  
Morphometric Characteristics ◽  
Structural Adaptation ◽  
Solid Soil ◽  
Similar Body ◽  
Structural Adaptations

The article presents the results of studies of anatomical, histological and morphometric characteristics of bovine ungulates aimed at identifying signs of structural adaptation of the distal part of the limb to anthropogenically modeled content conditions. The factors that the hoof experiences are the predominance of static load, the high weight of the animal, and the support on solid soil. As a morphological control, elk is considered as a parrotfish animal with similar body size and weight, located in the conditions of natural biotsenose and moving on forest soils. It is shown that constant presence of cattle in conditions of hypokinesia on hard floors leads to change of limb setting and change of hoof shape, which is reflected in change of hoof shape, increase of hoof angle, ratio of plantar and dorsal hoof surfaces length. At the same time, the biomechanical load is redistributed between parts of the hoof so that the load on the wall increases and on the ball decreases. This may be a factor predisposing the hoof to the appearance of microtraumas, later manifested by laminites.

Servitisation through structural adaptation

2021 ◽  
Vol 31 (3) ◽  
pp. 468-490
Author(s):  
Saad Zighan ◽  
Ziad Alkalha ◽  
David Bamford ◽  
Iain Reid ◽  
Zu'bi M.F. Al-Zu'bi
Keyword(s):  
Service Provision ◽  
Design Theory ◽  
Structural Changes ◽  
Oil And Gas ◽  
Project Managers ◽  
The Body ◽  
Exploratory Research ◽  
Organisational Structure ◽  
Structural Adaptation ◽  
Content Type

PurposeThe purpose of this study is to investigate the structural changes needed for project-based organisations (PBOs) to synthesise their project operations and services following the servitisation strategy. It addresses the question of how PBOs should change their organisational structure fitting with service provision strategy.Design/methodology/approachThis study followed an exploratory research method using a single in-depth case with evidence collected from 51 project managers from five different industry sectors: construction, oil and gas, IT, logistics and health careFindingsCapitalising on organisational design theory, it has been found that successfully extending PBOs' outcomes into a system of both project output and extra services requires an adjustment of organisational structure that creates greater value for both companies and customers. This required adjustment has been divided into five main categories: (1) collaboration cross-project and customers; (2) flexible workflow, (3) decentralised decision-making, (4) wide span of control and (5) project governance. However, the findings indicate that success can only be ensured by particular mutually coordinated organisational designs with a suitable balance of products and servicesPractical implicationsThis study presents vital indicators to PBOs practitioners when deploying servitisation within their operational strategy by adjusting the organisation's design.Social implicationsServitisation could add both economic and social values for a diverse set of project stakeholders. However, the sustainability performance of servitisation in servitised project-based organisations is an outcome of reducing the discrepancy between project operation and service provision activities.Originality/valueThis study contributes to the body of knowledge and proposes a structural alteration process in PBOs to help align project operations and service provision activities. It explains how project-based organisations reconfigure their resources to provide services.

HISTOCHEMICAL AND STRUCTURAL ADAPTATION OF SKELETAL MUSCLE TO BODY SUSPENSION IN SPONTANEOUSLY HYPERTENSIVE RATS.

1995 ◽  
Vol 27 (Supplement) ◽  
pp. S181
Author(s):  
S. Ogoh ◽  
S. Yamasaki ◽  
H. Okamoto ◽  
S. Fukuda ◽  
S. Tsuchikura ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Spontaneously Hypertensive Rats ◽  
Structural Adaptation ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

scholarly journals BEHAVIORAL FUNCTIONS IMPLEMENTATION ON SPIKING NEURAL NETWORKS

2021 ◽  
Vol 20 (3) ◽  
pp. 591-622
Author(s):  
Anton Korsakov ◽  
Aleksandr Bakhshiev ◽  
Lyubov Astapova ◽  
Lev Stankevich
Keyword(s):  
Neural Networks ◽  
Conditioned Reflex ◽  
Negative Reinforcement ◽  
Input Pulse ◽  
Compartmental Models ◽  
Structural Adaptation ◽  
Spike Model ◽  
Current State ◽  
Proposed Model ◽  
Spiking Model

The question of behavioral functions modeling of animals (in particular, the modeling and implementation of the conditioned reflex) is considered. The analysis of the current state of neural networks with the possibility of structural reconfiguration is carried out. The modeling is carried out by means of neural networks, which are built on the basis of a compartmental spiking model of a neuron with the possibility of structural adaptation to the input pulse pattern. The compartmental spike model of a neuron is able to change its structure (the size of the cell body, the number and length of dendrites, the number of synapses) depending on the incoming pulse pattern at its inputs. A brief description of the compartmental spiking model of a neuron is given, and its main features are noted in terms of the possibility of its structural reconfiguration. The method of structural adaptation of the compartmental spiking model of the neuron to the input pulse pattern is described. To study the work of the proposed model of a neuron in a network, the choice of a conditioned reflex as a special case of the formation of associative connections is justified as an example. The structural scheme and algorithm of formation of a conditioned reflex with both positive and negative reinforcement are described. The article presents a step-by-step description of experiments on the associative connection’s formation in general and conditioned reflex (both with positive and negative reinforcement), in particular. The conclusion is made about the prospects of using spiking compartmental models of neurons to improve the efficiency of the implementation of behavioral functions in neuromorphic control systems. Further promising directions for the development of neuromorphic systems based on spiking compartmental models of the neuron are considered.

scholarly journals Climate Change Adaptation of Geo-Structures in Europe: Emerging Issues and Future Steps

Geosciences ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 488
Author(s):  
Alessandra Insana ◽  
Mary Antonette Beroya-Eitner ◽  
Marco Barla ◽  
Hauke Zachert ◽  
Bojan Žlender ◽  
...  
Keyword(s):  
Climate Change ◽  
Climate Change Impacts ◽  
Structural Adaptation ◽  
Hazard Risk ◽  
Emerging Issues ◽  
Assessment And Monitoring ◽  
The Subject ◽  
Geographical Scope ◽  
Potential Climate Change ◽  
Hazard Risk Assessment

Climate change is already being felt in Europe, unequivocally affecting the regions’ geo-structures. Concern over this is rising, as reflected in the increasing number of studies on the subject. However, the majority of these studies focused only on slopes and on a limited geographical scope. In this paper, we attempted to provide a broader picture of potential climate change impacts on the geo-structures in Europe by gathering the collective view of geo-engineers and geo-scientists in several countries, and by considering different geo-structure types. We also investigated how geo-structural concerns are being addressed in national adaptation plans. We found that specific provisions for geo-structural adaptation are generally lacking and mainly come in the form of strategies for specific problems. In this regard, two common strategies are hazard/risk assessment and monitoring, which are mainly implemented in relation to slope stability. We recommend that in future steps, other geo-structures are likewise given attention, particularly those assessed as also potentially significantly affected by climate change. Countries considered in this study are mainly the member countries of the European Large Geotechnical Institutes Platform (ELGIP).

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