Tau 64 and Tau 69: Two Early Biochemical Markers of Neurofibrillary Degeneration

1989 ◽  
pp. 39-55 ◽  
Author(s):  
A. Delacourte ◽  
S. Flament ◽  
A. Défossez ◽  
L. Buee ◽  
B. Hémon ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Neurofibrillary Degeneration

6 Pathological Tau proteins are biochemical markers that differentiate several types of neurofibrillary degeneration

1996 ◽  
Vol 17 (4) ◽  
pp. S2
Author(s):  
A. Delacourte ◽  
N. Sergeant ◽  
V. Buée-Scherrer ◽  
L. Buée ◽  
J.-P. David ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Tau Proteins ◽  
Neurofibrillary Degeneration

Specific biochemical markers of bone metabolism and cytokine study confirm the diagnosis of malignant infantile osteopetrosis at birth using cord blood sample

Pathology ◽  
2005 ◽  
Vol 37 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Michael Chan ◽  
Wong K. ◽  
Iris Chan ◽  
Y. F. Luo ◽  
Sidney Tam ◽  
...  
Keyword(s):  
Cord Blood ◽  
Blood Sample ◽  
Bone Metabolism ◽  
Biochemical Markers ◽  
Cord Blood Sample

Results of study of biochemical markers of bone metabolism in men with coronary heart disease

2020 ◽  
pp. 39-43
Author(s):  
A. V. Voronkina ◽  
T. A. Raskina ◽  
M. V. Letaeva ◽  
Yu. V. Averkieva ◽  
O. S. Malyshenko ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Bone Formation ◽  
Bone Metabolism ◽  
Biochemical Markers ◽  
Coronary Atherosclerosis ◽  
Cathepsin K ◽  
Arterial Calcification ◽  
Mineral Density ◽  
Bone Remodeling Markers

The development of atherosclerosis is closely related to the calcification of the vessel intima and fibrous plaques, being a complex and multifactorial process, in which the markers of bone formation and resorption play an important role. Objective. To study the biochemical markers of bone metabolism in men with stable coronary heart disease (CHD). Material and methods. The study included 102 men with verified CHD. Data were evaluated by densitometry, coronary angiography, multispiral computed tomography, color duplex scanning of brachiocephalic arteries, serum lipids (total cholesterol, triglycerides [TG], high-density [LHD] and low-density lipoprotein cholesterol), concentrationsin the blood of osteocalcin (OC), bone alkaline phosphatase (BAP), cathepsin K and C-telopeptides (CTx). Results. Concentrations of BAP, cathepsin K and CTx in patients with CHD were significantly higher than in men without CHD. The concentration of OC in men with normal bone mineral density was significantly lower than in patients with osteopenic syndrome. There was a direct correlation between OC and antiatherogenic HDL cholesterol and the inverse correlation between OC and TG, CTx and TG. There was no correlation between the level of bone remodeling markers and coronary artery (CA) lesion variant and the severity of coronary atherosclerosis on SYNTAX scale. The correlation analysis did not reveal the connection of biochemical markers of bone metabolism with the severity of coronary atherosclerosis and calcification and thickness of intima-media complex of carotid arteries. Absolute values of bone formation indices (BAP, OC) were significantly higher in patients with severe СA calcification than in patients without signs of calcification. Summary. Increased rates of osteogenesis and osteoresorption characterize the accelerated process of bone metabolism and indicate in favor of high rates of bone loss in men with CHD, which confirms the likelihood of common pathophysiological mechanisms of bone resorption and arterial calcification.

A 6-month intervention study with vibration therapy in severely disabled children: effects on bone, biochemical markers and acceptance

2013 ◽  
Author(s):  
Swolin-Eide Diana ◽  
Braathen Gunnar ◽  
Emilsson Roger ◽  
Glansen Ulla ◽  
Soderpalm Ann-Charlott ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Intervention Study ◽  
Disabled Children ◽  
Bone Biochemical Markers ◽  
Vibration Therapy

Biochemical Markers in Patients Undergoing Cardiac Surgery

2006 ◽  
Vol 0 (2) ◽  
pp. 76
Author(s):  
Bernard Lewis Croal ◽  
Jane D McNeilly ◽  
◽  
Keyword(s):  
Cardiac Surgery ◽  
Biochemical Markers

Littoral invertebrates in waders’ nutrition at migratory stopover sites in the Azov and Black Sea region

2014 ◽  
Vol 25 (1-2) ◽  
pp. 69-82 ◽  
Author(s):  
L. P. Kharchenko ◽  
I. A. Lykova
Keyword(s):  
Fatty Acids ◽  
Black Sea ◽  
Biochemical Markers ◽  
Artemia Salina ◽  
Total Lipids ◽  
Long Distance ◽  
Black Sea Region ◽  
Stopover Sites ◽  
Littoral Invertebrates ◽  
Migratory Stopover

Seasonal migration for birds – distant migrants are the most energy intensive. Fat reserves accumulated in the bird’s body before migration and during migratory stopovers determine success of the long-distance flight. Lipids play a vital role both as a source of energy and as structural components of cell membranes. For most migrants to the speed and quality processes fat accumulation affects the feed ration in the field of migration stops. Fodder saturation with essential polyunsaturated fatty acids (PUFAs) is of great importance. Being paramount for physiological processes, these acids cannot be synthesized in the bird’s body. The proposed article is dedicated to the study of waders’ trophic relationships with their prey items, and the use of PUFAs as biochemical markers. This approach is based on the specificity of the fatty acids contained in the lipids of invertebrate to be used as food bird species studied. Significant amount NPZHK waders obtained from forage that can be considered PUFAs as biochemical markers to determine the range and diversity of food producing birds PUFAs ways, and also to study the food chain in ecosystems. A fatty acid spectrum (FAS) of the lipids common for nine littoral invertebrate species (Gammarus aequicauda, Idotea balthica, Artemia salina, Nerеis sp., Nerеis zonata, Theodoxces astrachanicus, Hydrobia acuta, Chironomus salinarius, Chironomus plumosus), which constitute the main component of waders’ diet at the migratory stopover sites in the Azov and Black Sea region, has been studied. Found that the largest amount of total lipids contained in Nereis zonata (4,6 %) and Artemia salina (4,4 %), the lowest amount of total lipids was observed in Chironomus (1,5–1,8 %), which implies that polychaete worms and Artemia salina, as a source of fat, are the most productive for waders. Our research has found that mollusks, polychaete worms, and Artemia salina are the most effective waders’ fodder in the PUFAs content. Mollusks contain the largest amount of PUFAs, their spectrum is ω3 and ω6 PUFAs, especially arаchidonic acid C20:4. Polychate worms are also characterized by a high PUFAs level; they serve for birds as a source of linolenic and linoleic acid groups. Artemia salina contains a large amount of eicosapentaenoic С20:5ω3 and docosahexaenoic С22:6ω3 acids, which getting to an organism of birds, participating in the formation of cell membranes, act as thermal stabilizer lipid bilayers, enhance stamina during long-distance flight. A high abundance of Artemia salina in the feeding areas permit tundra waders to use them as a prey item, which can fulfill the bird’s body with a required amount of fatty acids in a short time. We have established an influence of some environmental factors, as water temperature and salinity, on the lipids FAS of littoral invertebrates. Spectrum analysis of polyene fatty acids in the lipids closely related species of invertebrates living in different salinity water showed that the content of PUFAs in the lipid depend on their food spectrum, and the environmental conditions. Therefore, anthropogenic pressure and changes of water hydrological regime may affect PUFAs content in the lipids of littoral invertebrates. In its turn, this factor may change alimentary behavior and migratory strategy of the birds, which use migratory stopover sites in the region in question. Shallow waters of the Azov-Black Sea region are characterized by different climatic characteristics and a large reserve of phytoplankton. This explains the mass character species studied of invertebrates to feeding areas and their use as basic prey items, many species of waders.

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