Neuroimaging Using Nuclear Magnetic Resonance and Computerized Tomography in Patients with Multiple Sclerosis, Idiopathic Optic Neuritis, and Systemic Lupus Erythematosus

Neurology ◽  
1986 ◽  
pp. 463-468
Author(s):  
L. Jacobs ◽  
P. R. Kinkel ◽  
W. R. Kinkel ◽  
F. A. Green ◽  
P. Costello
1984 ◽  
Vol 2 (2) ◽  
pp. 155-156
Author(s):  
M. Vermess ◽  
R.M. Bernstein ◽  
G.M. Bydder ◽  
R.E. Steiner ◽  
I.R. Young ◽  
...  

2010 ◽  
Vol 37 (11) ◽  
pp. 2259-2267 ◽  
Author(s):  
MARTA GONZÀLEZ ◽  
JOSEP RIBALTA ◽  
GLÒRIA VIVES ◽  
SIMONA IFTIMIE ◽  
RAIMÓN FERRÉ ◽  
...  

Objective.Patients with systemic lupus erythematosus (SLE) have accelerated atherosclerosis. Since the conventional lipid profile (total plasma cholesterol, triglycerides, low and high density lipoprotein cholesterol) is not consistently altered in SLE, we hypothesized that investigation of lipoprotein subclasses would improve prediction of risk of atherosclerosis in these patients.Methods.As a quantitative index of atherosclerosis, we measured the carotid intima-media thickness (IMT) in 68 patients with SLE and related the atherosclerosis to a detailed lipoprotein profile generated using nuclear magnetic resonance (NMR). We measured the cholesterol transported by the pool of remnant lipoproteins (RLPc) and evaluated the modulatory effect of the APOE genotype on the lipoprotein subclass profile and atherosclerosis associated with SLE.Results.Circulating lipoprotein remnant particles [RLPc and intermediate density lipoprotein (IDL)] were positively correlated with IMT, and among them, the indicator that explained 20.2% of the variability in carotid atherosclerosis measured in these patients was IDL, as assessed by NMR. Carriers of the APOE2 allele were at increased risk due to a significant accumulation of IDL particles.Conclusion.Lipoprotein subclasses are more associated with subclinical atherosclerosis in patients with SLE than the lipid variables that are routinely measured. The IDL fraction, which is significantly modulated by the APOE genotype, is the most strongly, significantly, and positively correlated with IMT.


1983 ◽  
Vol 7 (3) ◽  
pp. 461-467 ◽  
Author(s):  
M. Vermess ◽  
R. M. Bernstein ◽  
G. M. Bydder ◽  
R. E. Steiner ◽  
I. R. Young ◽  
...  

Author(s):  
Stephen Oppenheimer ◽  
B.I. Hoffbrand

ABSTRACT:The optic neuritis of systemic lupus erythematosus (S.L.E.) more frequently results in the persistence of a central scotoma or complete blindness after a single attack than demyelinating optic neuritis, although the initial clinical presentations may be identical. A significant number of patients, however, recover normal vision. Optic neuritis may be the presenting symptom of S.L.E. and as myelopathy may also occur in the course of the disease, confusion with multiple sclerosis may result, especially if there are no arthritic, cutaneous nor visceral manifestations. We report a case of lupus optic neuritis associated with anticardiolipin antibodies and a circulating lupus anticoagulant and suggest these may be a marker for vasculitic optic neuritis and play a role in its aetiology.


2021 ◽  
pp. 33-36
Author(s):  
María Isabel Quaglia ◽  
Carla Gobbi ◽  
Carla Alonso ◽  
Yohana Tissera ◽  
Rosa Figueroa ◽  
...  

Non compacted cardiomyopathy (NCNC) frequently represents an abnormality of myocardial morphology associated with a genetic etiology, however, there are few descriptions of its association with autoimmune diseases. We present a review of the literature and the case of a lupus patient who was admitted with signs of decompensated heart failure with confirmation of VINC by echocardiography and cardiac nuclear magnetic resonance (C-MRI).


1987 ◽  
Vol 30 (8) ◽  
pp. 947-950 ◽  
Author(s):  
Jay G. Kenik ◽  
Kelly Krohn ◽  
Richard B. Kelly ◽  
Martin Bierman ◽  
Michael D. Hammeke ◽  
...  

2006 ◽  
Vol 45 (2) ◽  
pp. 121-121 ◽  
Author(s):  
Takeo Sato ◽  
Satoko Unno ◽  
Kiyofumi Hagiwara ◽  
Hiroaki Matsuno ◽  
Katsuhiko Takeda ◽  
...  

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