scholarly journals Non compacted cardiomyopathy as a cause of insufficiency cardiac in Systemic Lupus Erythematosus

2021 ◽  
pp. 33-36
Author(s):  
María Isabel Quaglia ◽  
Carla Gobbi ◽  
Carla Alonso ◽  
Yohana Tissera ◽  
Rosa Figueroa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systemic Lupus Erythematosus ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Decompensated Heart Failure ◽  
Review Of The Literature ◽  
Systemic Lupus ◽  
Genetic Etiology ◽  
Myocardial Morphology

Non compacted cardiomyopathy (NCNC) frequently represents an abnormality of myocardial morphology associated with a genetic etiology, however, there are few descriptions of its association with autoimmune diseases. We present a review of the literature and the case of a lupus patient who was admitted with signs of decompensated heart failure with confirmation of VINC by echocardiography and cardiac nuclear magnetic resonance (C-MRI).

Nuclear magnetic resonance (NMR) imaging of the brain in systemic lupus erythematosus

1984 ◽  
Vol 2 (2) ◽  
pp. 155-156
Author(s):  
M. Vermess ◽  
R.M. Bernstein ◽  
G.M. Bydder ◽  
R.E. Steiner ◽  
I.R. Young ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Nmr Imaging ◽  
Systemic Lupus ◽  
The Brain ◽  
Nuclear Magnetic

Heart failure imaging patterns in systemic lupus erythematosus. Evaluation using cardiovascular magnetic resonance

2014 ◽  
Vol 176 (2) ◽  
pp. 559-561 ◽  
Author(s):  
Sophie Mavrogeni ◽  
Georgia Karabela ◽  
Efthymios Stavropoulos ◽  
Sotiris Plastiras ◽  
George Spiliotis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systemic Lupus Erythematosus ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Systemic Lupus

Nuclear Magnetic Resonance Lipoprotein Subclasses and the APOE Genotype Influence Carotid Atherosclerosis in Patients with Systemic Lupus Erythematosus

2010 ◽  
Vol 37 (11) ◽  
pp. 2259-2267 ◽  
Author(s):  
MARTA GONZÀLEZ ◽  
JOSEP RIBALTA ◽  
GLÒRIA VIVES ◽  
SIMONA IFTIMIE ◽  
RAIMÓN FERRÉ ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Carotid Atherosclerosis ◽  
Apoe Genotype ◽  
Density Lipoprotein ◽  
Systemic Lupus ◽  
Lipoprotein Subclasses ◽  
Nuclear Magnetic

Objective.Patients with systemic lupus erythematosus (SLE) have accelerated atherosclerosis. Since the conventional lipid profile (total plasma cholesterol, triglycerides, low and high density lipoprotein cholesterol) is not consistently altered in SLE, we hypothesized that investigation of lipoprotein subclasses would improve prediction of risk of atherosclerosis in these patients.Methods.As a quantitative index of atherosclerosis, we measured the carotid intima-media thickness (IMT) in 68 patients with SLE and related the atherosclerosis to a detailed lipoprotein profile generated using nuclear magnetic resonance (NMR). We measured the cholesterol transported by the pool of remnant lipoproteins (RLPc) and evaluated the modulatory effect of the APOE genotype on the lipoprotein subclass profile and atherosclerosis associated with SLE.Results.Circulating lipoprotein remnant particles [RLPc and intermediate density lipoprotein (IDL)] were positively correlated with IMT, and among them, the indicator that explained 20.2% of the variability in carotid atherosclerosis measured in these patients was IDL, as assessed by NMR. Carriers of the APOE2 allele were at increased risk due to a significant accumulation of IDL particles.Conclusion.Lipoprotein subclasses are more associated with subclinical atherosclerosis in patients with SLE than the lipid variables that are routinely measured. The IDL fraction, which is significantly modulated by the APOE genotype, is the most strongly, significantly, and positively correlated with IMT.

scholarly journals Combined Brain/Heart Magnetic Resonance Imaging in Systemic Lupus Erythematosus

2020 ◽  
Vol 16 (3) ◽  
pp. 178-186 ◽  
Author(s):  
Sophie Mavrogeni ◽  
Loukia Koutsogeorgopoulou ◽  
Theodoros Dimitroulas ◽  
George Markousis-Mavrogenis ◽  
Kyriaki Boki ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Heart Failure ◽  
Systemic Lupus Erythematosus ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Cardiac Involvement ◽  
Brain Mri ◽  
Resonance Imaging ◽  
Systemic Lupus ◽  
Neuropsychiatric Sle

: Cardiovascular Disease (CVD) in Systemic Lupus Erythematosus (SLE) and Neuropsychiatric SLE (NPSLE) has an estimated prevalence of 50% and 40%, respectively and both constitute major causes of death among SLE patients. In this review, a combined brain/heart Magnetic Resonance Imaging (MRI) for SLE risk stratification has been proposed. : The pathophysiologic background of NPSLE includes microangiopathy, macroscopic infarcts and accelerated atherosclerosis. Classic brain MRI findings demonstrate lesions suggestive of NPSLE in 50% of the NPSLE cases, while advanced MRI indices can detect pre-clinical lesions in the majority of them, but their clinical impact still remains unknown. Cardiac involvement in SLE includes myo-pericarditis, valvular disease/endocarditis, Heart Failure (HF), coronary macro-microvascular disease, vasculitis and pulmonary hypertension. Classic and advanced Cardiovascular Magnetic Resonance (CMR) indices allow function and tissue characterization for early diagnosis and treatment follow-up of CVD in SLE. : Although currently, there are no clinical data supporting the combined use of brain/heart MRI in asymptomatic SLE, it may have a place in cases with clinical suspicion of brain/heart involvement, especially in patients at high risk for CVD/stroke such as SLE with antiphospholipid syndrome (SLE/APS), in whom concurrent cardiac and brain lesions have been identified. Furthermore, it may be of value in SLE with multi-organ involvement, NPSLE with concurrent cardiac involvement, and recent onset of arrhythmia and/or heart failure.

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