Effects of Growth Hormone on Bone and Calcium Metabolism in Older People

1993 ◽  
pp. 302-306
Author(s):  
R. Marcus ◽  
L. Holloway ◽  
G. Butterfield
Keyword(s):  
Growth Hormone ◽  
Older People ◽  
Calcium Metabolism

Growth Hormone Administration and Exercise Effects on Muscle Fiber Type and Diameter in Moderately Frail Older People

2001 ◽  
Vol 49 (7) ◽  
pp. 852-858 ◽  
Author(s):  
James V. Hennessey ◽  
Joseph A. Chromiak ◽  
Shirley DellaVentura ◽  
Steven E. Reinert ◽  
Jacqueline Puhl ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Older People ◽  
Muscle Fiber ◽  
Fiber Type ◽  
Muscle Fiber Type ◽  
Frail Older People ◽  
Growth Hormone Administration ◽  
Hormone Administration

Regulation of Calcium Metabolism

1976 ◽  
Vol 13 (1-6) ◽  
pp. 518-539 ◽  
Author(s):  
R. G. G. Russell
Keyword(s):  
Growth Hormone ◽  
Calcium Metabolism ◽  
Gonadal Steroids ◽  
Renal Handling ◽  
Renal Metabolism ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D ◽  
Clinical Disorders ◽  
The Relationship

This paper reviews the regulation of calcium metabolism in man. The body's calcium economy is determined by the relationship between the intestinal absorption of calcium, the renal handling of calcium, and by the movements of calcium in and out of the skeleton. These processes are influenced by many factors, the most important of which are parathyroid hormone and the hormones derived from the renal metabolism of vitamin D, notably 1,25-dihydroxyvitamin D8. The role of endogenous calcitonin in man is still controversial, but there are several other hormones which have some influence on calcium metabolism, including thyroid hormone, growth hormone, and the adrenal and gonadal steroids. Clinical disorders of calcium metabolism and their treatment are discussed in terms of the disturbances in normal physiology they represent.

Effects of Growth Hormone in Older People

1994 ◽  
pp. 150-154 ◽  
Author(s):  
Robert Marcus ◽  
Leah Holloway ◽  
Gail E. Butterfield
Keyword(s):  
Growth Hormone ◽  
Older People

scholarly journals HOMOLOGOUS RECOMBINANT GROWTH HORMONE AND CALCIUM METABOLISM IN THE TILAPIA, OREOCHROMIS MOSSAMBICUS, ADAPTED TO FRESH WATER

1993 ◽  
Vol 185 (1) ◽  
pp. 107-119 ◽  
Author(s):  
G. Flik ◽  
W. Atsma ◽  
J. C. Fenwick ◽  
F. Rentier-Delrue ◽  
J. Smal ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Calcium Metabolism ◽  
Calcium Influx ◽  
Oreochromis Mossambicus ◽  
The Body ◽  
Hepatosomatic Index ◽  
Gh Treatment ◽  
Recombinant Growth Hormone ◽  
Total Body Calcium ◽  
Treated Fish

Homologous recombinant tilapia growth hormone (rtGH) was tested for its effects on calcium metabolism in freshwater tilapia Oreochromis mossambicus. Fish were fed an optimal ration of 5 % of their body mass per day. A positive correlation was found between the amount of food given and the branchial calcium influx. In male tilapia, the mean calcium influxes were 5.80 and 11.71 micromole h-1 100 g-1 when they were fed 2 % and 5 % food, respectively. In female fish fed 5 % food, the calcium influx was 6.20 micromole h-1 100 g-1. Calcium influx via the gills was not affected by rtGH. However, in rtGH-treated fish, the net efflux of calcium was lower than in the controls. Apparently, the calcium taken up from the water was more efficiently stored in the body. GH increased the hepatosomatic index and had mild growth-promoting effects (mass and length increases); it increased the total body calcium pool without affecting bone or scale calcium density. The chloride cell density in the opercular epithelium almost doubled after GH treatment. GH did not influence plasma ion composition. Plasma cortisol levels were lower in rtGH-treated fish. A comparison of the roles of GH and prolactin (the products of the prolactin gene family) in calcium regulation of the tilapia led us to conclude that GH has specific calcitropic effects on freshwater tilapia that differ from those of prolactin.

scholarly journals The effect of growth hormone on calcium metabolism in the sheep

1975 ◽  
Vol 33 (3) ◽  
pp. 309-314 ◽  
Author(s):  
G. D. Braithwaite
Keyword(s):  
Growth Hormone ◽  
Bone Resorption ◽  
Calcium Metabolism ◽  
Nutrient Balance ◽  
Subcutaneous Administration ◽  
Bovine Growth Hormone ◽  
Hormone Production ◽  
Exchangeable Ca ◽  
Balance Technique

1. The effect of subcutaneous administration of bovine growth hormone on calcium metabolism of nearly mature wether sheep has been studied by a combination of a radioactive technique and a nutrient balance technique.2. Administration of growth hormone resulted in a significant increase in the rates of absorption of Ca, accretion of Ca into bone, resorption of Ca from bone and skeletal retention of Ca, and also in the sizes of the exchangeable Ca pools.3. Retention of phosphorus was also significantly increased.4. These changes suggest that the effect of growth hormone was to alter the Ca metabolism of nearly mature wethers to resemble that of younger, more actively growing animals.5. Results are consistent with the theory that oestrogens may alter Ca metabolism of wethers by increasing growth hormone production.

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