Analytical Methods for Biotechnology Products

Biotechnology products: validation of analytical methods

Specification of Drug Substances and Products ◽

10.1016/b978-0-08-102824-7.00022-1 ◽

2020 ◽

pp. 587-603

Author(s):

Jennifer E. Dally ◽

Myrna A. Monck

Keyword(s):

Analytical Methods ◽

Biotechnology Products

Download Full-text

Historical Development of Analytical Methods for Anti-Doping Control

Physical Education and Sport Through the Centuries ◽

10.1515/spes-2016-0018 ◽

2017 ◽

Vol 4 (1) ◽

pp. 15-23

Author(s):

Emilija Stojanović ◽

Dragan Radovanović

Keyword(s):

Analytical Methods ◽

Historical Development ◽

Technological Progress ◽

Doping Control ◽

Scientific Cooperation ◽

High Quality ◽

Biotechnology Products ◽

International Scientific Cooperation

AbstractAlthough the fight against the use of doping in sport has been going on for almost 90 years, its effects have become tangible in the last 45 years only, thanks to the use of valid and sensitive analytical methods. Historically, extensive international scientific cooperation and technological progress have laid down the basis for the development of high quality doping control laboratories worldwide. New biotechnology products are constantly being discovered and are made available on the doping market, so that anti-doping approaches must be raised to a higher level, and analytical methods must be constantly improved and refined, since it has bacome obvious that to some extent they lag behind new sophisticated doping agents. However, all the methods must first be scientifically proven and tested in order to be adequately used against doping in sport. If the technology and systematic use of the latest scientific anti-doping knowledge continue to develop and advance, it will greatly contribute to the development of analytical methods.

Download Full-text

Stereo modeling of HVEM specimens by serial tilting and computer graphics

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100141913 ◽

1986 ◽

Vol 44 ◽

pp. 34-35

Author(s):

J.R. McIntosh ◽

D.L. Stemple ◽

William Bishop ◽

G.W. Hannaway

Keyword(s):

Computer Graphics ◽

Analytical Methods ◽

Photographic Film ◽

Complex Structures ◽

Multiple Objects ◽

Multiple Images ◽

3 Dimensional

EM specimens often contain 3-dimensional information that is lost during micrography on a single photographic film. Two images of one specimen at appropriate orientations give a stereo view, but complex structures composed of multiple objects of graded density that superimpose in each projection are often difficult to decipher in stereo. Several analytical methods for 3-D reconstruction from multiple images of a serially tilted specimen are available, but they are all time-consuming and computationally intense.

Download Full-text