Reference Values for Lung Density and Structure Measured by Quantitative CT

1994 ◽  
pp. 290-298 ◽  
Author(s):  
W. A. Kalender ◽  
H. Fichte ◽  
W. Bautz ◽  
A. Zwick ◽  
R. Rienmüller ◽  
...  
Keyword(s):  
Reference Values ◽  
Quantitative Ct ◽  
Lung Density

scholarly journals Quantitative CT lung densitometry for the diagnosis of bronchiolitis obliterans in children

2021 ◽  
Author(s):  
Hye Jin Lee ◽  
Seong koo Kim ◽  
Jae Wook Lee ◽  
Soo Ah Im ◽  
Nack Gyun Chung ◽  
...  
Keyword(s):  
Bronchiolitis Obliterans ◽  
Multivariate Logistic Regression Analysis ◽  
Retrospective Chart Review ◽  
Relative Volume ◽  
Chest Ct ◽  
Airflow Limitation ◽  
Quantitative Ct ◽  
Lung Density ◽  
Volume Percentage ◽  
The Difference

Background: The purpose of this study was to evaluate the quantitative diagnostic performance of computed tomography (CT) densitometry in pediatric bronchiolitis obliterans (BO) patients. Methods: A retrospective chart review was performed on 109 children under age 18 who underwent 3D chest CT from March 2019 to March 2021. We measured the mean lung density (MLD) and calculated the difference of MLD (MLDD) in expiratory and inspiratory phase, the expiratory to inspiratory ratio of mean lung density (E/I MLD), and the relative volume percentage of lung density at 50 HU intervals (E600 to E950). We calculated the sensitivity, specificity, and diagnostic accuracy of lung density indices for the diagnosis of BO. Results: A total of 81 patients, 51 BO patients and 30 controls, were included in this study (mean age: 12.7 vs 11.4 years). Expiratory (EXP) MLD, MLDD, E/I MLD, and E900 were all statistically significantly worse in the BO group. Multivariate logistic regression analysis showed that MLDD (odds ratio [OR] = 0.98, p < .001), E/I MLD (OR = 1.39, p < .001), and E850 (OR = 1.54, p = 0.003) were significant densitometry parameters for BO diagnosis. In ROC analysis, E900 (cut-off 1.4%; AUC = 0.920), E/I MLD (cut-off 0.87; AUC = 0.887), and MLDD (cut-off 109 HU; AUC = 0.867) showed high accuracy in diagnosis of BO. Conclusion: The quantification of lung density with chest CT complements the diagnosis by providing additional indications of expiratory airflow limitation in pediatric BO patients.

A comparison of CT lung voxel density analysis in a blast and non blast injured casualty.

2018 ◽  
Vol 165 (3) ◽  
pp. 166-168
Author(s):  
Sebastian Bourn ◽  
T E Scott ◽  
E J Hulse
Keyword(s):  
Lung Injury ◽  
Three Dimensional ◽  
High Morbidity ◽  
Quantitative Ct ◽  
Lung Density ◽  
Blast Exposure ◽  
Blast Lung Injury ◽  
Density Analysis ◽  
Assisted Diagnosis ◽  
Trauma Ct

IntroductionPrimary blast lung injury (PBLI) is a prominent feature in casualties following exposure to blast. PBLI carries high morbidity and mortality, but remains difficult to diagnose and quantify. Radiographic diagnosis of PBLI was historically made with the aid of plain radiographs; more recently, qualitative review of CT images has assisted diagnosis.MethodsWe report a novel way of measuring post-traumatic acute lung injury using CT lung density analysis in two casualties. One casualty presented following blast exposure with confirmed blast lung injury and the other presented following extremity injury without blast exposure. Three-dimensional lung maps of each casualty were produced from their original trauma CT scan. Analysis of the lung maps allowed quantitative radiological comparison exposing areas of reduced aeration of the patient’s lungs.Results45% of the blast-exposed lungs were non-aerated compared with 10% in the non-blast-exposed lungs.DiscussionIn these example cases quantitative CT lung density analysis allowed blast-injured lungs to be distinguished from non-blast-exposed lungs.

scholarly journals Association of quantitative CT lung density measurements and lung function decline in World Trade Center workers

2020 ◽  
Author(s):  
Xiaoyu Liu ◽  
Anthony P. Reeves ◽  
Katherine Antoniak ◽  
Raúl San José Estépar ◽  
John T. Doucette ◽  
...  
Keyword(s):  
Lung Function ◽  
World Trade ◽  
World Trade Center ◽  
Lung Function Decline ◽  
Quantitative Ct ◽  
Lung Density ◽  
Density Measurements ◽  
Trade Center

Measurement of Lung Density by Means of Quantitative CT Scanning

CHEST Journal ◽  
1992 ◽  
Vol 102 (3) ◽  
pp. 805-811 ◽  
Author(s):  
André Heremans ◽  
Johny A. Verschakelen ◽  
Luc Van fraeyenhoven ◽  
Maurits Demedts
Keyword(s):  
Ct Scanning ◽  
Quantitative Ct ◽  
Lung Density

scholarly journals Quantitative CT Reference Values for Vertebral Trabecular Bone Density in Children and Young Adults

Radiology ◽  
2009 ◽  
Vol 250 (1) ◽  
pp. 222-227 ◽  
Author(s):  
Vicente Gilsanz ◽  
Francisco J. Perez ◽  
Patricia P. Campbell ◽  
Frederick J. Dorey ◽  
David C. Lee ◽  
...  
Keyword(s):  
Young Adults ◽  
Bone Density ◽  
Trabecular Bone ◽  
Reference Values ◽  
Trabecular Bone Density ◽  
Quantitative Ct ◽  
Vertebral Trabecular Bone ◽  
Children And Young Adults

EURRECA’s Approach for Estimating Micronutrient Requirements

2011 ◽  
Vol 81 (4) ◽  
pp. 256-263 ◽  
Author(s):  
Christophe Matthys ◽  
Pieter van ‘t Veer ◽  
Lisette de Groot ◽  
Lee Hooper ◽  
Adriënne E.J.M. Cavelaars ◽  
...  
Keyword(s):  
Reference Values ◽  
Policy Decision ◽  
Individual Variability ◽  
The Body ◽  
Decision Makers ◽  
Nutrient Requirements ◽  
Factorial Approach ◽  
Dietary Reference Values ◽  
Health Policy Decision ◽  
Quantitative Integration

In Europe, micronutrient dietary reference values have been established by (inter)national committees of experts and are used by public health policy decision-makers to monitor and assess the adequacy of diets within population groups. The approaches used to derive dietary reference values (including average requirements) vary considerably across countries, and so far no evidence-based reason has been identified for this variation. Nutrient requirements are traditionally based on the minimum amount of a nutrient needed by an individual to avoid deficiency, and is defined by the body’s physiological needs. Alternatively the requirement can be defined as the intake at which health is optimal, including the prevention of chronic diet-related diseases. Both approaches are confronted with many challenges (e. g., bioavailability, inter and intra-individual variability). EURRECA has derived a transparent approach for the quantitative integration of evidence on Intake-Status-Health associations and/or Factorial approach (including bioavailability) estimates. To facilitate the derivation of dietary reference values, EURopean micronutrient RECommendations Aligned (EURRECA) is developing a process flow chart to guide nutrient requirement-setting bodies through the process of setting dietary reference values, which aims to facilitate the scientific alignment of deriving these values.

Pediatric reference values for insulin from oGTT and prevalence of hyperinsulinemia in obese children

2014 ◽  
Vol 9 (S 01) ◽  
Author(s):  
A Körner ◽  
K Scheuermann ◽  
M Neef ◽  
E Sergeyev ◽  
M Vogel ◽  
...  
Keyword(s):  
Reference Values ◽  
Obese Children
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