Tumour Markers in the Diagnosis and Management of Patients with Hepatocellular Carcinoma

1986 ◽  
pp. 68-72 ◽  
Author(s):  
P. J. Johnson
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumour Markers ◽  
Diagnosis And Management

scholarly journals Elevation of tumour markers TGF-β, M2-PK, OV-6 and AFP in hepatocellular carcinoma (HCC)-induced rats and their suppression by microalgae Chlorella vulgaris

BMC Cancer ◽  
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Khaizurin Tajul Arifin ◽  
Suhaniza Sulaiman ◽  
Suhana Md Saad ◽  
Hanafi Ahmad Damanhuri ◽  
Wan Zurinah Wan Ngah ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Chlorella Vulgaris ◽  
Tumour Markers

scholarly journals Saudi Guidelines for the Diagnosis and Management of Hepatocellular Carcinoma: Technical Review and Practice Guidelines

2012 ◽  
Vol 32 (2) ◽  
pp. 174-199 ◽  
Author(s):  
Ayman A. Abdo ◽  
Mazen Hassanain ◽  
AbdulRahman AlJumah ◽  
Ashwaq Al Olayan ◽  
Faisal M. Sanai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Practice Guidelines ◽  
Diagnosis And Management ◽  
Technical Review

Management of hepatocellular carcinoma

2021 ◽  
Vol 4 (1) ◽  
pp. 19-25
Author(s):  
Salem Youssef Mohamed
Keyword(s):  
Hepatocellular Carcinoma ◽  
At Risk ◽  
Liver Cancer ◽  
Early Diagnosis ◽  
Primary Liver Cancer ◽  
Screening Programs ◽  
Diagnosis And Management

Hepatocellular carcinoma (HCC) is a heterogeneous disease that develops most of the time on diseases liver. Early diagnosis and management are the best options for the patients, so screening programs are mandatory for those who are at risk of the development of HCC. Despite the challenge of management of HCC, there is hopeful management for HCC as the field of primary liver cancer has moved quickly

scholarly journals Sinusoidal Endothelial Cell Progenitor Cells Promote Tumour Progression in Patients with Hepatocellular Carcinoma

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Ya-xing Feng ◽  
Wei Li ◽  
Xu-dong Wen ◽  
Ning Zhang ◽  
Wei-hui Liu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Endothelial Cell ◽  
Progenitor Cells ◽  
Tumour Progression ◽  
Clinicopathological Characteristics ◽  
Tumour Markers ◽  
Sinusoidal Endothelial Cell ◽  
Liver Tumours ◽  
Expression Levels ◽  
Poorly Differentiated

Objective. As sinusoidal endothelial cell progenitor cells (SEPCs) play a significant role in liver regeneration, it is necessary to elucidate whether SEPCs participate in tumour progression of hepatocellular carcinoma (HCC). Methods. A total of 45 patients with primary HCC who underwent liver resection were included in this study. The liver tumours were removed from the patients, and partial tissues were prepared to identify SEPCs through double staining of CD133/CD45 and CD133/CD31 at the same location. Blood samples were collected to examine liver function parameters and tumour markers. The demographics and clinicopathological characteristics of the patients were collected for correlation analysis with SEPCs. Results. SEPCs were observed in several blood vessels within the HCC nodules of all 45 patients, but no SEPCs were detected in the tumour-adjacent tissues. The number of SEPCs was correlated with the expression levels of HCC tumour markers α-fetoprotein (AFP) and CA199. There was a positive correlation between the expression of SEPC markers and diameter of HCC tumours in differently differentiated specimens ( P < 0.01 ). The expression levels of SEPC markers were significantly higher in patients with poorly differentiated HCC than in patients with moderately and highly differentiated HCC ( P < 0.05 ). Conclusions. SEPCs are closely associated with HCC progression; therefore, SEPCs may be considered potential prognostic and metastatic biomarkers and therapeutic candidates for HCC.

Current approaches to the diagnosis and management of hepatocellular carcinoma

2005 ◽  
Vol 5 (1) ◽  
pp. 1-13 ◽  
Author(s):  
J. F. Perry ◽  
H. Poustchi ◽  
J. George ◽  
G. C. Farrell ◽  
G. W. McCaughan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diagnosis And Management

scholarly journals Diagnosis and management of hepatocellular carcinoma: results of a consensus meeting of The Ottawa Hospital Cancer Centre

2010 ◽  
Vol 17 (2) ◽  
Author(s):  
T. Asmis ◽  
F. Balaa ◽  
L. Scully ◽  
D. Papadatos ◽  
C. Marginean ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Consensus Meeting ◽  
Cancer Centre ◽  
Diagnosis And Management ◽  
Ottawa Hospital
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