What Does Pharmaceutical Industry Expect of Patenting Human Genes and Living Organisms?

Author(s):  
B. Garthoff
Author(s):  
Friedrich Vogel ◽  
Reinhard Grunwald
Keyword(s):  

2022 ◽  
Vol 4 (1) ◽  
pp. 013-018
Author(s):  
Mohini Chandrashekhar Upadhye ◽  
Mohini Chetan Kuchekar ◽  
Rohini Revansiddhappa Pujari ◽  
Nutan Uttam Sable

Biopolymers are compounds prepared by using various living organisms, including plants. These are composed of repeated units of the same or similar structure (monomers) linked together. Rubber, starch, cellulose, proteins and DNA, RNA, chitin, and peptides are some of the examples of natural biopolymers. Biopolymers are a diverse and remarkably versatile class of materials that are either produced by biological systems or synthesize from biological sources. Biopolymers are used in pharmaceutical industry and also in food industry.Naturally derived polymers are also used for conditioning benefits in hair and skin care. Biopolymers have various applications in medicine, food, packaging, and petroleum industries. This review article is focused on various aspects of biopolymers with a special emphasis on role of biopolymers in green nanotechnology and agriculture.


Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 486
Author(s):  
Jonas Schaub ◽  
Achim Zielesny ◽  
Christoph Steinbeck ◽  
Maria Sorokina

Natural products (NPs), biomolecules produced by living organisms, inspire the pharmaceutical industry and research due to their structural characteristics and the substituents from which they derive their activities. Glycosidic residues are frequently present in NP structures and have particular pharmacokinetic and pharmacodynamic importance as they improve their solubility and are often involved in molecular transport, target specificity, ligand–target interactions, and receptor binding. The COlleCtion of Open Natural prodUcTs (COCONUT) is currently the largest open database of NPs, and therefore a suitable starting point for the detection and analysis of the diversity of glycosidic residues in NPs. In this work, we report and describe the presence of circular, linear, terminal, and non-terminal glycosidic units in NPs, together with their importance in drug discovery.


2021 ◽  
Author(s):  
Jonas Schaub ◽  
Achim Zielesny ◽  
Christoph Steinbeck ◽  
Maria Sorokina

AbstractNatural products (NP), biomolecules produced by living organisms, inspire the pharmaceutical industry and research due to their structural characteristics and the substituents from which they derive their activities. Glycosidic residues are frequently present in NP structures and have particular pharmacokinetic and pharmacodynamic importance as they improve their solubility and are often involved in molecular transport, target specificity, ligand-target interactions and receptor binding. The COlleCtion of Open Natural prodUcTs (COCONUT) is currently the largest open database of NP and therefore a suitable starting point for the detection and analysis of the diversity of glycosidic residues in NP. In this work, we report and describe the presence of circular, linear, terminal and non-terminal glycosidic units in NP, together with their importance in drug discovery.


2021 ◽  
Vol 43 (3) ◽  
pp. 523-535 ◽  
Author(s):  
M. Aguirre-Ramírez ◽  
H. Silva-Jiménez ◽  
I. M. Banat ◽  
M. A. Díaz De Rienzo

AbstractMacromolecules are essential cellular components in biological systems responsible for performing a large number of functions that are necessary for growth and perseverance of living organisms. Proteins, lipids and carbohydrates are three major classes of biological macromolecules. To predict the structure, function, and behaviour of any cluster of macromolecules, it is necessary to understand the interaction between them and other components through basic principles of chemistry and physics. An important number of macromolecules are present in mixtures with surfactants, where a combination of hydrophobic and electrostatic interactions is responsible for the specific properties of any solution. It has been demonstrated that surfactants can help the formation of helices in some proteins thereby promoting protein structure formation. On the other hand, there is extensive research towards the use of surfactants to solubilize drugs and pharmaceuticals; therefore, it is evident that the interaction between surfactants with macromolecules is important for many applications which includes environmental processes and the pharmaceutical industry. In this review, we describe the properties of different types of surfactants that are relevant for their physicochemical interactions with biological macromolecules, from macromolecules–surfactant complexes to hydrophobic and electrostatic interactions.


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