Pathogenetic Mechanisms of Autoimmunity

1999 ◽  
pp. 26-37
Author(s):  
L. Adorini
Keyword(s):  
Pathogenetic Mechanisms

The Pathogenesis of Experimental Mycotic Encephalitis

1969 ◽  
Vol 27 ◽  
pp. 356-357
Author(s):  
James A. Swenberg ◽  
Adalbert Koestner ◽  
R.P. Tewari
Keyword(s):  
Electron Microscopy ◽  
Pathogenetic Mechanisms ◽  
Host Parasite

Previous investigations of pathogenetic mechanisms in mycotic encephalitis have been restricted to light microscopic and mycologic approaches. In this study, electron microscopy was utilized to determine the mode of vascular penetration and the cellular and subcellular host-parasite interrelationships in brains of mice infected with Oidiodendron kalrai. This newly isolated fungus was selected because of its ability to consistently produce encephalitis with gross and microscopic lesions similar to those observed in naturally occuring mycoses.

Endometrial hyperplasia (Clinical lecture)

2016 ◽  
pp. 10-18 ◽  
Author(s):  
I.B. Vovk ◽  
◽  
N.Е. Gorban ◽  
O.Ju. Borysiuk ◽  
◽  
...  
Keyword(s):  
Key Words ◽  
Hormonal Therapy ◽  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Diagnosis And Treatment ◽  
Pathogenetic Mechanisms ◽  
Endometrial Intraepithelial Neoplasia ◽  
Mechanisms Of Development ◽  
Clinical Lecture

In clinical lecture presents modern views of endometrial hyperplasia in terms of practitioner gynecologist. The problems of classification, pathogenetic mechanisms of development of endometrial hyperplasia. Particular attention is paid to modern approaches to diagnosis and treatment of endometrial hyperplasia. Key words: hyperplasia, endometrium, classification, endometrial hyperplasia, endometrial intraepithelial neoplasia, hormonal therapy.

Factors of humoral immunity in the combined course of vibration disease and hypertension

2020 ◽  
pp. 558-559
Author(s):  
R. A. Baraeva ◽  
L. A. Strizhakov ◽  
Y. I. Borzykh
Keyword(s):  
Humoral Immunity ◽  
Clinical Picture ◽  
Pathogenetic Mechanisms ◽  
Vibration Disease ◽  
Mechanisms Of Formation

The study of humoral immunity factors in vibration disease and its combination with hypertension opens up prospects for rehabilitation and treatment of patients with this pathology, as well as complements our knowledge of the pathogenetic mechanisms of formation of the clinical picture of these diseases.

Prostaglandin E1-Induced Hyperostosis: Clinicopathologic Correlations and Possible Pathogenetic Mechanisms

1996 ◽  
Vol 16 (3) ◽  
pp. 489-507 ◽  
Author(s):  
Ona Faye-Petersen ◽  
Walter Johnson ◽  
Waldemar Carlo ◽  
Gary Hedlund ◽  
Albert Pacifico ◽  
...  
Keyword(s):  
Prostaglandin E1 ◽  
Pathogenetic Mechanisms

scholarly journals Microfluidics in cardiovascular disease research: state of the art and future outlook

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Qingming Ma ◽  
Haixia Ma ◽  
Fenglan Xu ◽  
Xinyu Wang ◽  
Wentao Sun
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
State Of The Art ◽  
Drug Evaluation ◽  
Diagnostic Methods ◽  
Comprehensive Understanding ◽  
Pathogenetic Mechanisms ◽  
Disease Research ◽  
Delivery Vehicles ◽  
Primary Strategy

AbstractDue to extremely severe morbidity and mortality worldwide, it is worth achieving a more in-depth and comprehensive understanding of cardiovascular diseases. Tremendous effort has been made to replicate the cardiovascular system and investigate the pathogenesis, diagnosis and treatment of cardiovascular diseases. Microfluidics can be used as a versatile primary strategy to achieve a holistic picture of cardiovascular disease. Here, a brief review of the application of microfluidics in comprehensive cardiovascular disease research is presented, with specific discussions of the characteristics of microfluidics for investigating cardiovascular diseases integrally, including the study of pathogenetic mechanisms, the development of accurate diagnostic methods and the establishment of therapeutic treatments. Investigations of critical pathogenetic mechanisms for typical cardiovascular diseases by microfluidic-based organ-on-a-chip are categorized and reviewed, followed by a detailed summary of microfluidic-based accurate diagnostic methods. Microfluidic-assisted cardiovascular drug evaluation and screening as well as the fabrication of novel delivery vehicles are also reviewed. Finally, the challenges with and outlook on further advancing the use of microfluidics technology in cardiovascular disease research are highlighted and discussed.

The role of tryptophan in hepatic encephalopathy

1993 ◽  
Vol 5 (4) ◽  
pp. 71-75
Author(s):  
C. Aaldijk ◽  
W.W. Van Den Broek ◽  
R.C. Van Der Mast
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Picture ◽  
Serotonergic System ◽  
Pathogenetic Mechanisms ◽  
Research Findings ◽  
Glutamine Synthesis ◽  
The Brain ◽  
Tryptophan Uptake

SummaryIn this review the most important hypotheses for the occurrence of the clinical picture of hepatic encephalopathy are discussed. As possible pathogenetic mechanisms are raised: dysfunction of the serotonergic system due to an increased tryptophan uptake in the brain, an elevated intracerebral ammoniac concentration and glutamine synthesis, and a heightened intracerebral GABA-activity.The dysregulation of the serotonergic system as a consequence of the increased intracerebral tryptophan uptake is described as one of the most important pathogenetic mechanisms. The elevated intracerebral ammoniac concentration and the elevated intracerebral glutamine synthesis play in this a facilitating role. The similarity in symptomatology of the clinical picture of HE and the serotonergic syndrome support this hypothesis. Due to contradictory research findings the role of the GABA-ergic system and the occurrence of HE remains unclear.

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