Evidence-based Anticancer Materia Medica for Cervical Cancer

Author(s):  
Tatjana Stanojković ◽  
Aleksandra Konić-Ristić ◽  
Teodora Janković ◽  
Gordana Zdunić ◽  
Katarina Šavikin

Author(s):  
Marina Kochiyeva

Data on modern methodological approaches that are used in screening for cancer are summarized. General principles of organizing screening studies are examined from the perspective of evidence-based medicine, target population, research methods, and effectiveness of the implemented screening programs for breast cancer, cervical cancer, and colon cancer are determined.



2017 ◽  
Vol 6 (8) ◽  
pp. 2008-2014 ◽  
Author(s):  
Nicole G. Campos ◽  
Vivien Tsu ◽  
Jose Jeronimo ◽  
Mercy Mvundura ◽  
Jane J. Kim


2021 ◽  
Author(s):  
Paulo Cesar Morales Mayer ◽  
Caroline Amélia Gonçalves ◽  
Franz Porzsolt

Abstract Background: Evidence-Based healthcare deals basically with published clinical trials to guide the decision making on what treatment to use for any specific conditions.Aims: The present paper assessed the inclusion and exclusion criteria used in clinical trials of cervical cancer aiming at establishing a clear distinction between each criterion.Methods: We performed a bibliographical search in pubmed with the terms cervical cancer and treatment or therapy filtered for clinical trials with human subjects for the last ten years. A total of 30 papers were used extracting and classifying the inclusion and exclusion category according to the characteristic they described. Results: We found no clear parameter to establish which criteria could exclusively serve as inclusion or exclusion across the papers, about 56% of the categories identified were found either listed as inclusion or exclusion criteria or even as both in some cases.Conclusions: The key issue of selection criteria is not in its form but in its function, the first point to consider is if the trial is experimental (focused on efficacy and proof of principle) or observational (pragmatic trials, focused on effectiveness and real world conditions). We suggest, inclusion criteria should be broad, focused on the investigated condition; exclusion criteria should apply only to the subset of this “included” population, and do not take part in observational studies. These conclusions do not serve only for researchers but should affect practitioners and policy makers to correctly compare the results of investigated treatment.



Author(s):  
Eran Ben-Arye ◽  
Tamar Tadmor ◽  
Aaron Polliack ◽  
Elad Schiff


Author(s):  
Yi-Ren Chen ◽  
Pei-Wen Hsiao ◽  
Feng-Ming Lin ◽  
Guan-James Wu ◽  
Chin-Hsien Tsai


2012 ◽  
Vol 23 (2A) ◽  
pp. 62-76
Author(s):  
John Harvey Wingfield ◽  
Tabia Henry Akintobi ◽  
DeBran Jacobs ◽  
Marvella E. Ford


2020 ◽  
Vol 30 (4) ◽  
pp. 311-327 ◽  
Author(s):  
Kari Tanderup ◽  
Nicole Nesvacil ◽  
Kathrin Kirchheiner ◽  
Monica Serban ◽  
Sofia Spampinato ◽  
...  


2019 ◽  
Vol 7 (4) ◽  
pp. e000182
Author(s):  
William Cherniak ◽  
Nikki Tyler ◽  
Kriti Arora ◽  
Ilana Lapidos-Salaiz ◽  
Emma Sczudlo ◽  
...  

Human papillomavirus (HPV) vaccination campaigns to prevent cervical cancer are being considered and implemented in countries around the world. While vaccination will protect future generations, it will not help the millions of women currently infected, leading to an estimated 311 000 deaths per year globally. This paper examines a selection of strategies that when applied to both existing and new technologies, could accelerate access to HPV testing. Authors from the US Agency for International Development, the National Institutes of Health, and the Bridge to Health Medical and Dental, a non-governmental organisation, joined forces to propose a scalable and country-directed solution for preventing cervical cancer using an end-to-end approach. Collectively, the authors offer seven evidence-based strategies, that when used alone or in combination have the ability to reduce HPV-caused cervical cancer deaths and disability. These strategies include (1) consistent HPV test intervals to decrease HPV DNA test costs; (2) exploring market shaping opportunities; (3) employing iterative user research methodologies like human-centred design; (4) target product profiles for new HPV tests; (5) encouraging innovation around cervical cancer screen and treat programmes; (6) developing national cancer control plans; and (7) integrating cervical cancer screen and treat services into existing infrastructure. By using the strategies outlined here, in combination with HPV vaccination campaigns, national governments will be able to scale and expand cervical cancer screening programmes and provide evidence-based treatment programmes for HPV-infected women.



2014 ◽  
Vol 32 (25) ◽  
pp. 2687-2690 ◽  
Author(s):  
Bradley J. Monk ◽  
Krishnansu S. Tewari


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