Rationale and Design of a Trial to Evaluate the Cardiotoxocity of Weekly Schedules of Adriamycin, with Endomyocardial Biopsy used as an End Point

Author(s):  
F. M. Torti ◽  
B. Lum ◽  
M. R. Bristow ◽  
F. E. Stockdale ◽  
M. Kohler ◽  
...  
Author(s):  
Xia Mingyu ◽  
Ma Wengshu ◽  
Wu Xiangh ◽  
Chen Dong

This paper describes morphological and cytochemistry changes of endomyocardial biopsy in 94 patients. The samples of myoicardium were taken from 32 patients with dilated cardiomyopathy, and sdudied with light and electron microscop. The cytochemical studies in some of these patients were performed at histological and ultrastructure level. This paper also reported the result of myocardial biopsy in 33 patients with serious dysrythmia.The result of this controlled study indicates that morphological assessment in both cardiomyopathy and congenital or rheumatic heart diseases showed no special changes. In patients of dilated cardiomyopathy, the decreased activity of myosin ATPase was secondary to cardial failure. The change of succinate dehydrogenase (SDHase) was not significant with light microscopy. But ultrastructural localization of SDHase activity is valuable. Its activity was found to be localized in endomembrane and ridge of the mitochondria, the activity of this enzyme was decrease, normal, or increase. SDHase activity was more intense in cardial myocytes well-functioning, or ultrastructurally well preserved hearts.


1984 ◽  
Vol 2 (4) ◽  
pp. 647-656 ◽  
Author(s):  
William D. Edwards

2020 ◽  
Author(s):  
Keyword(s):  

2013 ◽  
Vol 5 (3) ◽  
pp. 193-197
Author(s):  
Emiko Ejima ◽  
Koichiroh Matsumura ◽  
Fumiyuki Hayashi ◽  
Kensaku Shibata ◽  
Masahiro Mizobuchi ◽  
...  

2019 ◽  
Vol 41 (4) ◽  
pp. 7-35
Author(s):  
Andrea Lynn Smith

The centerpiece of New York State’s 150th anniversary of the Sullivan Expedition of 1779 was a pageant, the “Pageant of Decision.” Major General John Sullivan’s Revolutionary War expedition was designed to eliminate the threat posed by Iroquois allied with the British. It was a genocidal operation that involved the destruction of over forty Indian villages. This article explores the motivations and tactics of state officials as they endeavored to engage the public in this past in pageant form. The pageant was widely popular, and served the state in fixing the expedition as the end point in settler-Indian relations in New York, removing from view decades of expropriations of Indian land that occurred well after Sullivan’s troops left.


2019 ◽  
Vol 3 ◽  
pp. 919
Author(s):  
Khairul Umami ◽  
Syawaludin A. Harahap ◽  
Mega Laksmini Syamsudin ◽  
Sunarto Sunarto

Pantai merupakan daerah yang sangat dinamis untuk berubah seiring bertambahnya waktu. Salah satu perubahan yang terjadi di daerah pantai yaitu perubahan pada garis pantai. Tujuan penelitian ini yaitu untuk mengetahui tingkat perubahan garis pantai di pesisir Kecamatan Sayung, Kabupaten Demak dari hasil overlay citra satelit Landsat. Penelitian ini diharapkan dapat berguna sebagai rujukan penelitian selanjutnya, serta sebagai informasi untuk instansi-instansi terkait dan pemerintah agar dapat memperhatikan kondisi keseimbangan fisik pantai di Pesisir Sayung. Penelitian ini menggunakan data yang bersumber dari citra Landsat 7 dan 8 dalam kurun waktu 10 tahun dari tahun 2006 sampai 2016. Metode yang digunakan yaitu metode deskriptif dengan menjelaskan masalah yang terjadi pada lokasi penelitian dengan pendekatan pemodelan dan sistematis. Metode analisis perubahan garis pantai dilakukan dalam program Digital Shoreline Analysis System (DSAS) dengan pendekatan statistik End Point Rate (EPR) dan Net Shorline Movement (NSM). Hasil penelitian menunjukkan bahwa perubahan garis pantai di pesisir Sayung didominasi dengan kejadian abrasi yang sangat tinggi dengan luasan abrasi bernilai 116,48 hektar. Abrasi maksimum terjadi di Desa Timbulsloko, Abrasi minimum terjadi di Desa Sriwulan, Akresi maksimum terjadi di Desa Sriwulan, dan Akresi minimum terjadi di Desa Bedono.


2020 ◽  
Vol 04 (05) ◽  
Author(s):  
Sander Trenson ◽  
Daniel Hofer ◽  
Mateusz Sokolski ◽  
Fran Mikulicic ◽  
Frank Ruschitzka ◽  
...  

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