Electrophysiological, Biochemical and Pharmacological Aspects of Reentrant Ventricular Arrhythmias in the Late Myocardial Infarction Period

1980 ◽  
pp. 104-133
Author(s):  
N. El-Sherif ◽  
J. A. C. Gomes ◽  
G. J. Kelen ◽  
R. G. Khan ◽  
P. S. Kang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Ventricular Arrhythmias

RESEARCH THE VALUE OF THE COMBINATION OF T WAVE ALTERNANS AND NT-PROBNT IN PREDICTING SUDDEN CARDIAC DEATH

2012 ◽  
pp. 74-83
Author(s):  
Anh Tien Hoang ◽  
Nhat Quang Nguyen
Keyword(s):  
Myocardial Infarction ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Ventricular Arrhythmias ◽  
Healthy Person ◽  
Treadmill Test ◽  
T Wave ◽  
T Wave Alternans

Background: Decades of research now link TWA with inducible and spontaneous clinical ventricular arrhythmias. This bench-to-bedside foundation makes TWA, NT-ProBNP a very plausible index of susceptibility to ventricular arrythmia, and motivates the need to define optimal combination of TWA and NT-ProBNP in predicting ventricular arrythmia in myocardial infarction patients. We research this study with 2 targets: 1. To evaluate the role of TWA in predicting sudden cardiac death in myocardial infarction patients. 2. To evaluate the role of NT-ProBNP in predicting sudden cardiac death in myocardial infarction patients 3. Evaluate the role of the combined NT-ProBNP and TWA in predicting sudden cardiac death in myocardial infarction patients. Methods: Prospective study with follow up the mortality in 2 years: 71 chronic myocardial infarction patients admitted to hospital from 5/2009 to 5/20011 and 50 healthy person was done treadmill test to caculate TWA; ECG, echocardiography, NT-ProBNP. Results: Cut-off point of NT-ProBNP in predicting sudden cardiac death is 3168 pg/ml; AUC = 0,86 (95% CI: 0,72 - 0,91); Cut-off point of TWA in predicting sudden cardiac death is 107 µV; AUC = 0,81 (95% CI: 0,69 - 0,87); NT-ProBNP can predict sudden cardiac death with OR= 7,26 (p<0,01); TWA can predict sudden cardiac death with OR= 8,45 (p<0,01). The combined NT-ProBNP and TWA in predicting ventricular arrythmia in heart failure patients: OR= 17,91 (p<0,001). Conclusions: The combined NT-ProBNP and TWA have the best predict value of sudden cardiac death in myocardial infarction patients, compare to NT-ProBNP or TWA alone

Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: Results from the GUSTO-III trial

2003 ◽  
Vol 145 (3) ◽  
pp. 515-521 ◽  
Author(s):  
Sana M. Al-Khatib ◽  
Amanda L. Stebbins ◽  
Robert M. Califf ◽  
Kerry L. Lee ◽  
Christopher B. Granger ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Ventricular Arrhythmias

The Efficacy of Ajmaline in Ventricular Arrhythmias after Failure of Lidocaine Therapy in the Acute Phase of Myocardial Infarction

Angiology ◽  
1983 ◽  
Vol 34 (3) ◽  
pp. 204-214 ◽  
Author(s):  
E. Grenadier ◽  
G. Alpan ◽  
S. Keidar ◽  
D. Weiss ◽  
A. Marmor ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Phase ◽  
Ventricular Arrhythmias

Adjacent QT dispersion: A good predictor of ventricular arrhythmias after myocardial infarction

Open Medicine ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. 179-182 ◽  
Author(s):  
Mohammad Ostovan ◽  
Shahdad Khosropanah ◽  
Shohreh Hooshmand
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Qt Interval ◽  
Regional Variation ◽  
Ventricular Arrhythmias ◽  
Qt Dispersion ◽  
Maximum Difference ◽  
Simple Method ◽  
Qtc Dispersion ◽  
Surface Electrocardiogram

AbstractThe 12-lead surface electrocardiogram adjacent QTc dispersion, which is the maximum difference of corrected QT interval between two adjacent leads, is a simple method to determine regional variation in repolarization and refractoriness. The aim of this study is to evaluate adjacent QTc dispersion as a marker of susceptibility to ventricular arrhythmias after myocardial infarction. A total of 135 consecutive patients with acute myocardial infarction were enrolled in the study. Adjacent QTc, measured by lens magnifier, was calculated on the first, second and third days after acute myocardial infarction. On the second day after acute myocardial infarction, adjacent QTc dispersion was significantly greater in patients with ventricular arrhythmias (P < 0.001). Adjacent QTc dispersion on the first and fifth day after acute myocardial infarction was not associated with development of ventricular arrhythmias. On the second day after acute myocardial infarction, adjacent QTc dispersion is a simple and feasible method for prediction of ventricular arrhythmias.

scholarly journals Long-term benefit of 1-year amiodarone treatment for persistent complex ventricular arrhythmias after myocardial infarction.

Circulation ◽  
1993 ◽  
Vol 87 (2) ◽  
pp. 309-311 ◽  
Author(s):  
M E Pfisterer ◽  
W Kiowski ◽  
H Brunner ◽  
D Burckhardt ◽  
F Burkart
Keyword(s):  
Myocardial Infarction ◽  
Ventricular Arrhythmias ◽  
Amiodarone Treatment ◽  
Term Benefit

The effect of lidocaine when used as a local anesthetic or by intravenous injection

2021 ◽  
Vol 1 (4) ◽  
pp. 234-237
Author(s):  
Hamza Khalifa , ,, , Ibrahim ◽  
Abdulfatah Saed ◽  
Naser Ramdan R. Amaizah ◽  
Aejeeliyah Yousuf ◽  
Malak Abdalh Akim Esdera
Keyword(s):  
Myocardial Infarction ◽  
Local Anesthetic ◽  
Ventricular Arrhythmias ◽  
Rapid Onset ◽  
The Other ◽  
Important Class ◽  
Onset Of Action ◽  
Digitalis Poisoning ◽  
Duration Of Efficacy ◽  
Efficacy Profile

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and an intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for spinal and peridural anesthesias, however, lidocaine, on the other hand, has the advantage of a rapid onset of action. Adrenaline supplements could delay the resorption and the duration of efficacy could be doubled. Lidocaine is the most important class 1B antiarrhythmic drug: it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digitalis poisoning, cardioversion, or cardiac catheterization). However, a routine prophylactic administration is no longer recommended for acute cardiac infarction. The overall benefit of this measure is not convincing. Lidocaine has also been efficient in refractory cases of status epilepticus.

Sign in / Sign up

Export Citation Format

Share Document