Practical Studies on Multi-channel Operation of a Novel Highly Sensitive Quartz Crystal Microbalance-based Planar Biosensor

2002 ◽  
pp. 906-908
Author(s):  
Hiroyuki Sota ◽  
Hiroshi Yoshimine ◽  
Yasuro Shinohara ◽  
Lars Fägerstam ◽  
Patric Fricking ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Highly Sensitive

Miniaturized, highly sensitive single-chip multichannel quartz-crystal microbalance

2002 ◽  
Vol 81 (26) ◽  
pp. 5069-5071 ◽  
Author(s):  
Vu Ngoc Hung ◽  
Takashi Abe ◽  
Phan Ngoc Minh ◽  
Masayoshi Esashi
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Single Chip ◽  
Highly Sensitive

A highly sensitive quartz crystal microbalance sensor modified with antifouling microgels for saliva glucose monitoring

Nanoscale ◽  
2020 ◽  
Vol 12 (37) ◽  
pp. 19317-19324
Author(s):  
Qian Dou ◽  
Shiwen Wang ◽  
Zifeng Zhang ◽  
Yanxiang Wang ◽  
Zhipeng Zhao ◽  
...  
Keyword(s):  
Amino Acids ◽  
Quartz Crystal Microbalance ◽  
High Resistance ◽  
Quartz Crystal ◽  
Glucose Monitoring ◽  
Glucose Detection ◽  
Quartz Crystal Microbalance Sensor ◽  
Highly Sensitive

A microgels@amino acids@cross-linked-coated sensor was fabricated to realize saliva glucose detection as well as to provide high resistance to protein pollution.

Detecting odorous materials in water using quartz crystal microbalance sensors

2002 ◽  
Vol 45 (4-5) ◽  
pp. 201-206 ◽  
Author(s):  
S. Ogawa ◽  
I. Sugimoto
Keyword(s):  
Pattern Recognition ◽  
Water Vapor ◽  
Quartz Crystal Microbalance ◽  
Petroleum Hydrocarbons ◽  
Quartz Crystal ◽  
Sensor Response ◽  
Contaminated Water ◽  
Highly Sensitive ◽  
Sensor Cell ◽  
Benzene Concentration

Water drawn from rivers into purification plants must be checked for the presence of odorous materials because oil or organic-solvent contamination of the water may occur. If the detection of odorous materials in water is untimely or fails, the consequences can be serious. Therefore, the water must be checked continuously. We have developed a water-monitoring system that uses a highly sensitive electronic nose consisting of quartz crystal microbalance sensors to detect odorous materials in water. The nose is sensitive enough to detect petroleum hydrocarbons without water vapor at a low-ppb level. However, the nose is very sensitive to humidity and temperature. We have thus developed a method for accurately maintaining the humidity and temperature in the sensor cell. Experimental results show that the developed system can quickly detect contaminated water that was mixed with gasoline, kerosene, or benzene (concentration: several hundred ppb level), and we should be able to classify the pollutant by using pattern recognition of the dynamic sensor response.

scholarly journals Rapid and Simultaneous Quantification of 4 Urinary Proteins by Piezoelectric Quartz Crystal Microbalance Immunosensor Array

2006 ◽  
Vol 52 (12) ◽  
pp. 2273-2280 ◽  
Author(s):  
Yang Luo ◽  
Ming Chen ◽  
Qianjun Wen ◽  
Meng Zhao ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Clinical Chemistry ◽  
Label Free ◽  
Urinary Proteins ◽  
Quartz Crystals ◽  
Piezoelectric Quartz ◽  
Piezoelectric Immunosensor ◽  
Highly Sensitive ◽  
Piezoelectric Quartz Crystal

Abstract Background: Urinary proteins are predictive and prognostic markers for diabetes nephropathy. Conventional methods for the quantification of urinary proteins, however, are time-consuming, and most require radioactive labeling. We designed a label-free piezoelectric quartz crystal microbalance (QCM) immunosensor array to simultaneously quantify 4 urinary proteins. Methods: We constructed a 2 × 5 model piezoelectric immunosensor array fabricated with disposable quartz crystals for quantification of microalbumin, α1-microglobulin, β2-microglobulin, and IgG in urine. We made calibration curves after immobilization of antibodies at an optimal concentration and then evaluated the performance characteristics of the immunosensor with a series of tests. In addition, we measured 124 urine samples with both QCM immunosensor array and immunonephelometry to assess the correlation between the 2 methods. Results: With the QCM immunosensor array, we were able to quantify 4 urinary proteins within 15 min. This method had an analytical interval of 0.01–60 mg/L. The intraassay and interassay imprecisions (CVs) were <10%, and the relative recovery rates were 90.3%–109.1%. Nonspecificity of the immunosensor was insignificant (frequency shifts <20 Hz). ROC analyses indicated sensitivities were ≥95.8% and, specificities were ≥76.3%. Bland–Altman difference plots showed the immunosensor array to be highly comparable to immunonephelometry. Conclusions: The QCM system we designed has the advantages of being rapid, label free, and highly sensitive and thus can be a useful supplement to commercial assay methods in clinical chemistry.

A highly sensitive quartz-crystal microbalance for sputtering investigations in slow ion–surface collisions

1999 ◽  
Vol 70 (9) ◽  
pp. 3696-3700 ◽  
Author(s):  
G. Hayderer ◽  
M. Schmid ◽  
P. Varga ◽  
HP. Winter ◽  
F. Aumayr
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Highly Sensitive
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