A New 20 µm upper Limit for SGR A*

1994 ◽  
pp. 427-430 ◽  
Author(s):  
D. Gezari ◽  
L. Ozernoy ◽  
F. Varosi ◽  
C. McCreight ◽  
R. Joyce
Keyword(s):  
2020 ◽  
Vol 644 ◽  
pp. A105
Author(s):  
S. Elaheh Hosseini ◽  
Michal Zajaček ◽  
Andreas Eckart ◽  
Nadeen B. Sabha ◽  
Lucas Labadie

Context. The density of the ambient medium around a supermassive black hole (SMBH) and the way it varies with distance plays an important role in our understanding of the inflow-outflow mechanisms in the Galactic centre (GC). This dependence is often fitted by spherical power-law profiles based on observations in the X-ray, infrared (IR), submillimetre (submm), and radio domains. Aims. Nevertheless, the density profile is poorly constrained at the intermediate scales of 1000 Schwarzschild radii (Rs). Here we independently constrain the spherical density profile using the stellar bow shock of the star S2 which orbits the SMBH at the GC with the pericentre distance of 14.4 mas (∼1500 Rs). Methods. Assuming an elliptical orbit, we apply celestial mechanics and the theory of bow shocks that are at ram pressure equilibrium. We analyse the measured IR flux density and magnitudes of S2 in the L′-band (3.8 micron) obtained over seven epochs in the years between 2004–2018. We put an upper limit on the emission from S2’s associated putative bow shock and constrain the density profile of the ambient medium. Results. We detect no significant change in S2 flux density until the recent periapse in May 2018. The intrinsic flux variability of S2 is at the level of 2–3%. Based on the dust-extinction model, the upper limit on the number density at the S2 periapse is ∼1.87  ×  109 cm−3, which yields a density slope of at most 3.20. Using the synchrotron bow-shock emission, we obtain the ambient density of ≲1.01  ×  105 cm−3 and a slope of ≲1.47. These values are consistent with a wide variety of media from hot accretion flows to potentially colder and denser media comparable in properties to broad-line-region clouds. However, a standard thin disc can be excluded at the distance of S2’s pericentre. Conclusions. With the current photometry sensitivity of 0.01 mag, we are not able to make stringent constraints on the density of the ambient medium in the GC using S2-star observations. We can distinguish between hot accretion flows and thin, cold discs, where the latter can be excluded at the scale of the S2 periapse. Future observations of stars in the S cluster using instruments such as Mid-IR Extremely Large Telescope Imager and Spectrograph at Extremely Large Telescope with the photometric sensitivity of as much as 10−3 mag will allow the GC medium to be probed at intermediate scales at densities as low as ∼700 cm−3 in case of non-thermal bow-shock emission. The new instrumentation, in combination with discoveries of stars with smaller pericentre distances, will help to independently constrain the density profile around Sagittarius A* (Sgr A*).


Science ◽  
1993 ◽  
Vol 262 (5138) ◽  
pp. 1414-1416 ◽  
Author(s):  
D. C. Backer ◽  
J. A. Zensus ◽  
K. I. Kellermann ◽  
M. Reid ◽  
J. M. Moran ◽  
...  

2015 ◽  
Vol 54 (03) ◽  
pp. 106-111 ◽  
Author(s):  
S. L. Andersen ◽  
P. Laurberg

SummaryThyroid hormones are essential development factors and maternal thyroid dysfunction may cause pregnancy complications and diseases in the fetus/child. In the present review we discuss new data on the incidence of Graves'-Basedow disease (GBD) in and around pregnancy, and how hyperthyroidism may affect the risk of spontaneous abortion and stillbirth.A special concern in pregnant women is the potential side effects from the use of antithyroid drugs (ATDs). One type of side effects is the allergic/toxic reactions to the drugs, which seem to be similar in and outside pregnancy, and another is that ATDs tend to over treat the fetus when the mother with GBD is made euthyroid. To avoid fetal hypothyroidism, the lowest possible ATD dose should be used to keep maternal thyroid function at the upper limit of normality with low serum TSH. Birth defects after the use of methimazole (MMI) (or its prodrug carbimazole) have been considered to be very rare, and no risk has previously been associated with the use of propylthiouracil (PTU). However, a recent Danish national study found that 1/30 of children exposed to MMI in early pregnancy had birth defects associated with this, and many defects were severe. PTU exposure was associated with defects in 1/40, and these defects were less severe. Proposals are given on how to reduce the risk of ATD associated birth defects.


1985 ◽  
Vol 24 (03) ◽  
pp. 107-110
Author(s):  
M. Pääkkönen ◽  
S. Aukee ◽  
K. Korhonen ◽  
A. Pääkkönen ◽  
E. Länsimies ◽  
...  

SummaryIn this work the duodenogastric reflux was quantified as the amount of radioactivity entering the stomach after an i.v. administration of 99mmTc-HIDA in ulcer patients and in patients who had undergone BI gastrectomy. The results were compared with visual evidence of gastric activity in the gamma camera images and biochemical determination of gastric bile reflux. The method is useful in quantifying the reflux if the activity is above the background activity. It allows the determination of an upper limit for the reflux when the reflux is evident visually. Only two or three images are needed for the quantitation. No correlation was found between biochemical measurement of fasting bile reflux in the stomach and radioisotopic quantification.


2013 ◽  
Vol 41 (01) ◽  
pp. 31-36
Author(s):  
E. Kienzle ◽  
N. Becker

ZusammenfassungIm Rahmen einer Eliminationsdiät wird regelmäßig Pferdefleisch eingesetzt. Aus Gründen der Praktikabilität verwenden Tierbesitzer häufig kommerziell erhältliches Pferdefleisch aus der Dose. Aufgrund eines Berichts von Zervikalspondylosen bei einer auf Futtermittel allergischen Katze erfolgte eine Analyse verschiedener auf Pferdefleisch basierender Produkte hinsichtlich des Vitamin-AGehalts.In 14 Pferdefleischerzeugnissen wurde der Vitamin-A-Gehalt (Retinol) analysiert. Der Gehalt an umsetzbarer Energie wurde mithilfe von Schätzformeln auf Basis der Deklaration berechnet.In Produkten mit deklarierten Anteilen von Leber, Innereien oder tierischen Nebenprodukten konnten zum Teil erhebliche Vitamin-A-Gehalte festgestellt werden. Bei alleiniger Verfütterung eines dieser Produkte (Deckung des durchschnittlichen Energiebedarfs) würde die Vitamin-A-Versorgung nur knapp unter dem Safe Upper Limit der Katze sowie oberhalb des Safe Upper Limits beim Hund liegen.Bei All-Meat-Produkten sollte nicht nur die Deklaration, sondern auch der Inhalt näher betrachtet werden, um einen Hinweis auf eventuell hohe Leberanteile zu erhalten.Aufgrund der Ergebnisse ist eine exzessive Vitamin-A-Aufnahme bei langfristiger Verfütterung von Pferdefleischprodukten mit hohen Leberanteilen nicht auszuschließen.


1993 ◽  
Vol 69 (05) ◽  
pp. 430-435 ◽  
Author(s):  
Colin Longstaff ◽  
Man-Yu Wong ◽  
Patrick J Gaffney

SummaryAn international collaborative study has been carried out to investigate the reproducibility of hirudin assays in 13 laboratories using four recombinant hirudins and one natural, sulphated product. A simple assay procedure was proposed involving the titration of α-thrombin with inhibitor and measurement of residual activity using a chromogenic substrate. A standard α-thrombin preparation was supplied to ensure that this reagent was of uniform quality throughout the study. The method appeared to present no difficulties and laboratories reported similar potencies for the 5 hirudin samples, in line with expected values. This gave 200–222 Thrombin Inhibitory Units/ampoule (TIU/ampoule) of lyophilised hirudin, with geometric coefficient of variation (gcv) values ranging from 10.15–15.97%. This corresponds to specific activities of approximately 14,300–15,900 TIU/mg protein. This is close to the upper limit of previously reported values of specific activity. We conclude that the precision of this determination compared with the wider range of values in the literature (8,000–16,000 thrombin inhibitory units [TIU]/mg) results from the use of good quality standard α-thrombin by all laboratories. This study has important implications for hirudin standardisation.


2018 ◽  
Vol 6 (2) ◽  
pp. 14-35
Author(s):  
Jana Kesselová

Abstract The study focuses on the process of being aware of own I in children acquiring Slovak language at an early age and living in a Slovak family. The aim of the research is to understand the process of acquiring the means by which children refer to themselves in the interaction with an adult person. The research uses the qualitative longitudinal method of individual case study. A child’s speech is researched from the very first occurrence of a self-reference mean in 16th month up to the upper limit of early age (36th month) and all that is based on audio-visual records transcripts. The following are researched: (a) succession of self-reference means acquisition in early childhood, (b) function of self-reference linguistic means, (c) process of child’s self-awareness. The results obtained based on the linguistic data in Slovak language are compared with the results of similarly focused researches in English, French, Polish, Russian and Bulgarian language. The research reveals some constants in the development of self-reference instruments that can be observed throughout various language-cultural environments. The research is a part of solutions within the grant project VEGA 1/0099/16 Personal and Social Deixis in Slovak Language.


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