Grand Strategic Thoughts with a Global Vision

Author(s):  
Liang Qiao
Keyword(s):  
Mousaion ◽  
2020 ◽  
Vol 37 (2) ◽  
Author(s):  
Collence Takaingenhamo Chisita ◽  
Nyarai Patience Chibanda

The development of libraries in any country is critical for its socio-economic transformation especially during this 21st century era where access to information and knowledge underpins development. The International Federation of Library Associations and Institutions (IFLA) launched the Global Vision Project in 2017 as a way of strengthening library throughout the world. The project has seen over 190 countries participating worldwide. For most nations, especially those in the developing countries, this has indeed created platforms for strong and united library associations that are powering literate, informed and participative societies. A number of countries in Africa including Zimbabwe have taken the initiatives to participate in the IFLA Global Vision. This article seeks to examine the challenges and opportunities   for librarians in Zimbabwe in building a united library field. It will also scrutinize the road travelled by librarians in Zimbabwe in their pursuit of a vision to reposition their libraries on the global library landscape. The   article will also study the factors affecting the development of a unified library sector in Zimbabwe. It will also explore how the national professional association Zimbabwe Library Association (ZIMLA) can contribute towards a unified library profession through collaboration. The article also proposes a strategy to enhance cooperation among librarians in Zimbabwe.


2009 ◽  
Vol 10 (8) ◽  
pp. 772-774
Author(s):  
Leyre Zuniga ◽  
Begona Calvo

2014 ◽  
Vol 6 (1) ◽  
pp. 38-56 ◽  
Author(s):  
Ana López-Serrano ◽  
Riansares Muñoz Olivas ◽  
Jon Sanz Landaluze ◽  
Carmen Cámara
Keyword(s):  

2017 ◽  
Vol 110 ◽  
pp. 2-9 ◽  
Author(s):  
Philip C. Stevenson ◽  
Murray B. Isman ◽  
Steven R. Belmain

2011 ◽  
Vol 589 (14) ◽  
pp. 3419-3420
Author(s):  
Maxim Volgushev
Keyword(s):  

Rare Künste ◽  
2007 ◽  
pp. 367-384
Author(s):  
Franz Reitinger
Keyword(s):  

Viruses ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2197
Author(s):  
Célia Chamontin ◽  
Guillaume Bossis ◽  
Sébastien Nisole ◽  
Nathalie J. Arhel ◽  
Ghizlane Maarifi

Intrinsic immunity is orchestrated by a wide range of host cellular proteins called restriction factors. They have the capacity to interfere with viral replication, and most of them are tightly regulated by interferons (IFNs). In addition, their regulation through post-translational modifications (PTMs) constitutes a major mechanism to shape their action positively or negatively. Following viral infection, restriction factor modification can be decisive. Palmitoylation of IFITM3, SUMOylation of MxA, SAMHD1 and TRIM5α or glycosylation of BST2 are some of those PTMs required for their antiviral activity. Nonetheless, for their benefit and by manipulating the PTMs machinery, viruses have evolved sophisticated mechanisms to counteract restriction factors. Indeed, many viral proteins evade restriction activity by inducing their ubiquitination and subsequent degradation. Studies on PTMs and their substrates are essential for the understanding of the antiviral defense mechanisms and provide a global vision of all possible regulations of the immune response at a given time and under specific infection conditions. Our aim was to provide an overview of current knowledge regarding the role of PTMs on restriction factors with an emphasis on their impact on viral replication.


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