Cross Talk Between Aluminum and Genetic Susceptibility and Epigenetic Modification in Alzheimer’s Disease

2018 ◽  
pp. 173-191 ◽  
Author(s):  
Ruifeng Liang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Genetic Susceptibility ◽  
Cross Talk ◽  
Epigenetic Modification

scholarly journals Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease

2008 ◽  
Vol 173 (3) ◽  
pp. 665-681 ◽  
Author(s):  
Dun-Sheng Yang ◽  
Asok Kumar ◽  
Philip Stavrides ◽  
Jesse Peterson ◽  
Corrine M. Peterhoff ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cross Talk ◽  
Neuronal Apoptosis ◽  
Model Of Alzheimer’S Disease

scholarly journals Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins

PROTEOMICS ◽  
2014 ◽  
Vol 15 (2-3) ◽  
pp. 508-519 ◽  
Author(s):  
Eric B. Dammer ◽  
Andrew K. Lee ◽  
Duc M. Duong ◽  
Marla Gearing ◽  
James J. Lah ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Cross Talk ◽  
Small Heat Shock Proteins ◽  
Shock Proteins ◽  
Quantitative Phosphoproteomics

scholarly journals Impaired apoptosis in lymphoblasts from Alzheimer’s disease patients: Cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways

2007 ◽  
Vol 64 (11) ◽  
pp. 1437-1448 ◽  
Author(s):  
F. Bartolomé ◽  
N. de las Cuevas ◽  
Ú. Muñoz ◽  
F. Bermejo ◽  
Á. Martín-Requero
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Signaling Pathways ◽  
Cross Talk

scholarly journals P1-214: False Reassurance Following Genetic Susceptibility Testing for Alzheimer's Disease: Evidence from the REVEAL Study

2011 ◽  
Vol 7 ◽  
pp. S179-S180
Author(s):  
Margaret Bradbury ◽  
Clara Chen ◽  
Denise Lautenbach ◽  
Kurt Christensen ◽  
L. Cupples ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Genetic Susceptibility ◽  
Susceptibility Testing ◽  
Reveal Study ◽  
Genetic Susceptibility Testing

scholarly journals DNA Methylation: A Promising Approach in Management of Alzheimer’s Disease and Other Neurodegenerative Disorders

Biology ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 90
Author(s):  
Gagandeep Kaur ◽  
Suraj Singh S. Rathod ◽  
Mohammed M. Ghoneim ◽  
Sultan Alshehri ◽  
Javed Ahmad ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Dna Methylation ◽  
Neurodegenerative Diseases ◽  
Epigenetic Modification ◽  
Research Area ◽  
Potential Biomarker ◽  
Novel Biomarkers ◽  
Different Populations

DNA methylation, in the mammalian genome, is an epigenetic modification that involves the transfer of a methyl group on the C5 position of cytosine to derive 5-methylcytosine. The role of DNA methylation in the development of the nervous system and the progression of neurodegenerative diseases such as Alzheimer’s disease has been an interesting research area. Furthermore, mutations altering DNA methylation affect neurodevelopmental functions and may cause the progression of several neurodegenerative diseases. Epigenetic modifications in neurodegenerative diseases are widely studied in different populations to uncover the plausible mechanisms contributing to the development and progression of the disease and detect novel biomarkers for early prognosis and future pharmacotherapeutic targets. In this manuscript, we summarize the association of DNA methylation with the pathogenesis of the most common neurodegenerative diseases, such as, Alzheimer’s disease, Parkinson’s disease, Huntington diseases, and amyotrophic lateral sclerosis, and discuss the potential of DNA methylation as a potential biomarker and therapeutic tool for neurogenerative diseases.

O2-06-02: A genetic susceptibility locus for depression of Alzheimer's disease and Parkinson's disease

2008 ◽  
Vol 4 ◽  
pp. T143-T144
Author(s):  
Michael A. Slifer ◽  
Gary W. Beecham ◽  
Eden R. Martin ◽  
Gaofeng Wang ◽  
John R. Gilbert ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Parkinson’S Disease ◽  
Alzheimer's Disease ◽  
Parkinson's Disease ◽  
Genetic Susceptibility ◽  
Susceptibility Locus ◽  
Genetic Susceptibility Locus
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