scholarly journals Pharmacotherapy in Oral and Maxillofacial Surgery

Author(s):  
Latha P. Rao

AbstractThe field of pharmacology has always fascinated medical professionals—the ability to cure a disease by prescribing medicine is very tempting. Medical and surgical specialties benefit from the correct use of drugs, and oral and maxillofacial surgery (OMFS) is no exception. Antibiotics, analgesics, and anti-inflammatory drugs are among commonly prescribed medicines in a maxillofacial surgical practice. Umpteen number of literature studies are available on the usage of these medicines in maxillofacial surgery. A review of literature is attempted in this chapter to reach a consensus in matters pertaining to these drugs. The task was in no way an easy one as no two studies compared the same group of medicines or similar pharmacological properties. The key facts, which have emerged from this literature search, have been projected in this chapter.

2017 ◽  
Vol 158 (Supplement 3) ◽  
pp. 3-30
Author(s):  
László Hodinka ◽  
Géza Bálint ◽  
Erika Budai ◽  
Pál Géher ◽  
Renáta Papp ◽  
...  

Abstract: In this review the available evidences regarding the most frequently applied medication (peroral and transdermal non-steroidal anti-inflammatory agents) for the most frequent musculoskeletal complaints (regional pain syndromes) have been collected for the appropriate medical professionals who are most frequently faced with these conditions (general practitioners, rheumatologists, orthopedics, occupational and sports medicine experts). The special population at risk (with repeated and high energy overuse because of occupational or sport activities) and the pathology of their syndromes are identified. Mode of action, pharmacological properties of the non-steroidal anti-inflammatory drugs and the unwanted effects of their application especially in infants and elderly are highlighted. Recommendations of the general and specific pain management guidelines have been selected and listed in the review. Orv Hetil. 2017; 158(Suppl. 3): 3–30.


2010 ◽  
Vol 04 (01) ◽  
pp. 54 ◽  
Author(s):  
Oliver Findl ◽  

Topical ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs) are used in the treatment of post-operative ocular inflammation and pain following cataract surgery and for some other clinical applications of ophthalmology, including cystoid macular oedema. Products vary by their pharmacological properties, clinical efficacy and tolerability, which affect their place in therapy for new agents in Europe. The pharmacological properties of topical ophthalmic NSAIDs and their place in current treatment of post-operative ocular inflammation are discussed in this article, focussing on bromfenac, which has been submitted for approval by the European Medicines Agency (EMEA).


2020 ◽  
Vol 67 (3) ◽  
pp. 158-163
Author(s):  
Norika Katagiri ◽  
Ryutaro Sakai ◽  
Takashi Izutsu ◽  
Hiromasa Kawana ◽  
Shigekazu Sugino ◽  
...  

Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders of the gastrointestinal tract including ulcerative colitis (UC) and Crohn's disease. Pain management can be challenging in patients with IBD because there are limitations on the use of analgesics. Use of nonsteroidal anti-inflammatory drugs is not recommended in patients with IBD because there is risk of relapse of IBD and an overall increase in disease activity. Opioids, although frequently used for treating severe acute pain, can have additional risks and complications in patients with IBD such as ileus, toxic megacolon, and narcotic bowel syndrome. Furthermore, little information is available in the literature on pain management in these patients undergoing noncolorectal surgery. This report describes 2 patients with UC in whom postoperative pain following oral and maxillofacial surgery was managed by intravenous patient-controlled analgesia with pentazocine. Apart from the development of acute dystonia in 1 case that was likely due to the use of droperidol for prevention of postoperative nausea and vomiting, postoperative pain was well controlled by pentazocine in both patients without any complications or UC exacerbations.


2020 ◽  
Vol 38 (4) ◽  
pp. 197-204
Author(s):  
SM Anwar Sadat ◽  
Mushfiq H Shaikh ◽  
Manjula Attygalla ◽  
Naman R Rao ◽  
Toru Nagao ◽  
...  

Oral health professionals are at high risk of developing COVID-19 infection due to their practice of close proximity to the patients. Patients in daily dental practice can be seen with basic protection protocol. Routine and elective dental procedures should be cancelled during this pandemic situation and could be rescheduled when the situation eases. In practice, as of universal prevention strategy, all patients should be assumed as COVID-19 infected and treated accordingly. Adequate standards of hygiene and protection should be adopted for all patients to avoid potential transmission risks. During the COVID-19 pandemic, it would be crucial to categorize oral and maxillofacial surgery cases into: emergency case, urgent case, intermediate case and low priority cases. While there has been a growing literature suggesting the aspect of critical care associated in treating these patients, ample of evidence indicates how this COVID-19 pandemic will affect surgical practice. Here we highlight the current unfavorable situation due to COVID -19 and offer recommendations for changes to dental and maxillofacial surgical practices. J Bangladesh Coll Phys Surg 2020; 38(4): 197-204


2015 ◽  
Vol 5 ◽  
pp. 51-53
Author(s):  
Arunesh Kumar Tiwari ◽  
Balram ◽  
Sunit Kumar ◽  
Rashmi Tripathi

Author(s):  
Santhosh Kumar Mp

 Serratiopeptidase, a proteolytic enzyme derived from Serratia E-15 species enterobacteria, is widely used in medical field for its anti-inflammatory, anti-edemic properties, and analgesic properties. It is being used commonly in various specialties such as orthopedics, otolaryngology, gynecology, surgery, pulmonology, ophthalmology, and dentistry. Research has shown that serratiopeptidase is the most effective anti-inflammatory agent compared to other enzyme preparations. This article reviews the efficacy, safety, and applications of serratiopeptidase in oral surgery. This article also discusses the mechanism of action of serratiopeptidase, its contraindications and complications. From the recently published literature, it is clear that the role of serratiopeptidase as a therapeutic agent in oral and maxillofacial surgery is expanding and they hold a promising future as a broad-spectrum anti-inflammatory drug with minimal side effects and complications. Further, research will broaden their applications in the field of medicine and dentistry.


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