Segmentation of Blood Vessels, Optic Disc Localization, Detection of Exudates, and Diabetic Retinopathy Diagnosis from Digital Fundus Images

Author(s):  
Soham Basu ◽  
Sayantan Mukherjee ◽  
Ankit Bhattacharya ◽  
Anindya Sen
2020 ◽  
Vol 10 (4) ◽  
pp. 5986-5991
Author(s):  
A. N. Saeed

Artificial Intelligence (AI) based Machine Learning (ML) is gaining more attention from researchers. In ophthalmology, ML has been applied to fundus photographs, achieving robust classification performance in the detection of diseases such as diabetic retinopathy, retinopathy of prematurity, etc. The detection and extraction of blood vessels in the retina is an essential part of various diagnosing problems associated with eyes, such as diabetic retinopathy. This paper proposes a novel machine learning approach to segment the retinal blood vessels from eye fundus images using a combination of color features, texture features, and Back Propagation Neural Networks (BPNN). The proposed method comprises of two steps, namely the color texture feature extraction and training the BPNN to get the segmented retinal nerves. Magenta color and correlation-texture features are given as input to the BPNN. The system was trained and tested in retinal fundus images taken from two distinct databases. The average sensitivity, specificity, and accuracy obtained for the segmentation of retinal blood vessels were 0.470%, 0.914%, and 0.903% respectively. Results obtained reveal that the proposed methodology is excellent in automated segmentation retinal nerves. The proposed segmentation methodology was able to obtain comparable accuracy with other methods.


2010 ◽  
Vol 1 (3) ◽  
pp. 16-27 ◽  
Author(s):  
I. K. E. Purnama ◽  
K. Y. E. Aryanto ◽  
M. H. F. Wilkinson

Retinal blood vessels can give information about abnormalities or disease by examining its pathological changes. One abnormality is diabetic retinopathy, characterized by a disorder of retinal blood vessels resulting from diabetes mellitus. Currently, diabetic retinopathy is one of the major causes of human vision abnormalities and blindness. Hence, early detection can lead to proper treatment, and segmentation of the abnormality provides a map of retinal vessels that can facilitate the assessment of the characteristics of these vessels. In this paper, the authors propose a new method, consisting of a sequence of procedures, to segment blood vessels in a retinal image. In the method, attribute filtering with a so-called Max-Tree is used to represent the image based on its gray value. The filtering process is done using the branches filtering approach in which the tree branches are selected based on the non-compactness of the nodes. The selection is started from the leaves. This experiment was performed on 40 retinal images, and utilized the manual segmentation created by an observer to validate the results. The proposed method can deliver an average accuracy of 94.21%.


2015 ◽  
Vol 5 (1) ◽  
pp. 36
Author(s):  
Baha Sen ◽  
Kemal Akyol ◽  
Safak Bayir ◽  
Hilal Kaya

<p>Identifying the position of the optic disc on the retinal fundus image is a technique that is often used in medical diagnosis, treatment and monitoring processes. Determination of the intensity of the bright colors that belongs to the optic disc on a normal retinal image by the help of image processing algorithms is a fairly easy process. However, determining the optic disc on a retinal image including the diabetic retinopathy disease is a more difficult process. The reason for this difficulty is the existence of many regions that have the same light intensity in different parts of the retina. In this study, a new method for supplying the automatic determination of the optic disc in a recursive manner is proposed. By the help of OpenCV library, automatic determination process of the optic disc on the retinal fundus images including the diabetic retinopathy disease, has been implemented. Circular regions with maximum brightness values in the retinal images that were normalized and passed through the denoising process were determined and these regions were analyzed if they are optic disc or not. This process basically consists of two steps: In the first step, the possible optic disc candidate regions were determined recursively and in the second step, by the help of Gabor filter kernels, these regions were analyzed and it’s provided to decide if they are optic disc or not. This study is based on a dataset that has 89 images including diabetic retinopathy disease. Performance of this system is tested on these images and also on the images that the red, green, blue color channels and Contrast Limited Adaptive Histogram Equalization (CLAHE) retinas were obtained. Most accurate determination of the position of the optic disc is obtained with retinas, implemented process CLAHE, including the best success rate of 89.88%.</p><p> </p>Keywords: Optic disc, diabetic retinopathy, recursively, circular region, gabor filter kernels.


Mekatronika ◽  
2020 ◽  
Vol 2 (1) ◽  
pp. 68-72
Author(s):  
Abdulaziz Abdo Salman ◽  
Ismail Mohd Khairuddin ◽  
Anwar P.P. Abdul Majeed ◽  
Mohd Azraai Mohd Razman

Diabetes is a global disease that occurs when the body is disabled pancreas to secrete insulin to convert the sugar to power in the blood. As a result, some tiny blood vessels on the part of the body, such as the eyes, are affected by high sugar and cause blocking blood flow in the vessels, which is called diabetic retinopathy.  This disease may lead to permanent blindness due to the growth of new vessels in the back of the retina causing it to detach from the eyes. In 2016, 387 million people were diagnosed with Diabetic retinopathy, and the number is growing yearly, and the old detection approach becomes worse. Therefore, the purpose of this paper is to computerize the old method of detecting different classes of DR from 0-4 according to severity by given fundus images. The method is to construct a fine-tuned deep learning model based on transfer learning with dense layers. The used models here are InceptionV3, VGG16, and ResNet50 with a sharpening filter. Subsequently, InceptionV3 has achieved 94% as the highest accuracy among other models.  


2016 ◽  
Vol 76 (22) ◽  
pp. 23309-23331 ◽  
Author(s):  
Rui Wang ◽  
Linghan Zheng ◽  
Chaoqun Xiong ◽  
Chunfang Qiu ◽  
Huating Li ◽  
...  

Author(s):  
I. K. E. Purnama ◽  
K. Y. E. Aryanto ◽  
M. H. F. Wilkinson

Retinal blood vessels can give information about abnormalities or disease by examining its pathological changes. One abnormality is diabetic retinopathy, characterized by a disorder of retinal blood vessels resulting from diabetes mellitus. Currently, diabetic retinopathy is one of the major causes of human vision abnormalities and blindness. Hence, early detection can lead to proper treatment, and segmentation of the abnormality provides a map of retinal vessels that can facilitate the assessment of the characteristics of these vessels. In this paper, the authors propose a new method, consisting of a sequence of procedures, to segment blood vessels in a retinal image. In the method, attribute filtering with a so-called Max-Tree is used to represent the image based on its gray value. The filtering process is done using the branches filtering approach in which the tree branches are selected based on the non-compactness of the nodes. The selection is started from the leaves. This experiment was performed on 40 retinal images, and utilized the manual segmentation created by an observer to validate the results. The proposed method can deliver an average accuracy of 94.21%.


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