Background:
The currently available anti breast cancer agents as well as conventional drug delivery methods have some
limitations.
Objective:
In view of these limitations, researchers used phytochemicals/herbal extracts as anti-breast cancer agents together with the
polymeric nanoparticles to provide an effective way of targeted drug delivery with lesser /no side effects.
Methods:
The literature for this review was searched during the year 2014 to 2018 by using the keywords, ‘ ‘breast cancer’, ‘breast
cancer and its current treatments’, ‘plants against the breast cancer’, ‘polymeric nanoparticles’, ‘herbal based polymeric nanoparticles’.
The databases i.e. PubMed, Science Direct and Google Scholar were used for collecting the information.
Results:
In the present review, we try to summarize the potential of herbal based nanoformulation as specific and high efficacy therapeutic strategy in order to pave a way for the future research involving screening and use of herbal nanoparticles for the treatment of
breast cancer.
Conclusion:
The encapsulation of the herbal extract in the polymeric nanoparticles is the prominent, effective and emerging way of
targeted drug delivery for cancer. It may serve as safer way of targeted drug delivery and may be the answer of the complications related
to the currently available anti-breast cancer agents as well as limitations of conventional method of drug delivery.
Single-step surface functionalization of polymeric nanoparticles for targeted drug delivery
