Herbal Based Polymeric Nanoparticles as a Therapeutic Remedy for Breast Cancer

2020 ◽  
Vol 20 ◽  
Author(s):  
Mohd Mughees ◽  
Saima Wajid
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Polymeric Nanoparticles ◽  
Herbal Extract ◽  
Future Research ◽  
Delivery Methods ◽  
Cancer Breast ◽  
Conventional Drug ◽  
Targeted Drug

Background: The currently available anti breast cancer agents as well as conventional drug delivery methods have some limitations. Objective: In view of these limitations, researchers used phytochemicals/herbal extracts as anti-breast cancer agents together with the polymeric nanoparticles to provide an effective way of targeted drug delivery with lesser /no side effects. Methods: The literature for this review was searched during the year 2014 to 2018 by using the keywords, ‘ ‘breast cancer’, ‘breast cancer and its current treatments’, ‘plants against the breast cancer’, ‘polymeric nanoparticles’, ‘herbal based polymeric nanoparticles’. The databases i.e. PubMed, Science Direct and Google Scholar were used for collecting the information. Results: In the present review, we try to summarize the potential of herbal based nanoformulation as specific and high efficacy therapeutic strategy in order to pave a way for the future research involving screening and use of herbal nanoparticles for the treatment of breast cancer. Conclusion: The encapsulation of the herbal extract in the polymeric nanoparticles is the prominent, effective and emerging way of targeted drug delivery for cancer. It may serve as safer way of targeted drug delivery and may be the answer of the complications related to the currently available anti-breast cancer agents as well as limitations of conventional method of drug delivery.

Identification of protein targets and the mechanism of the cytotoxic action of Ipomoea turpethum extract loaded nanoparticles against breast cancer cells

2019 ◽  
Vol 7 (39) ◽  
pp. 6048-6063 ◽  
Author(s):  
Mohd Mughees ◽  
Mohd Samim ◽  
Yadhu Sharma ◽  
Saima Wajid
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Cells ◽  
Targeted Drug Delivery ◽  
Breast Cancer Cells ◽  
Cytotoxic Action ◽  
Protein Targets ◽  
Targeted Drug

The shortcomings of the currently available anti-breast cancer agents compel the development of the safer targeted drug delivery for the treatment of breast cancer.

ROS-Switchable Polymeric Nanoplatform with Stimuli-Responsive Release for Active Targeted Drug Delivery to Breast Cancer

2017 ◽  
Vol 9 (14) ◽  
pp. 12227-12240 ◽  
Author(s):  
Yu Zhang ◽  
Qin Guo ◽  
Sai An ◽  
Yifei Lu ◽  
Jianfeng Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Stimuli Responsive ◽  
Targeted Drug

scholarly journals Targeted Drug Delivery Systems Mediated by a Novel Peptide in Breast Cancer Therapy and Imaging

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e66128 ◽  
Author(s):  
Ruei-Min Lu ◽  
Min-Shan Chen ◽  
De-Kuan Chang ◽  
Chien-Yu Chiu ◽  
Wei-Chuan Lin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Breast Cancer Therapy ◽  
Targeted Drug ◽  
Targeted Drug Delivery Systems

Synthesis of a novel, sequentially active-targeted drug delivery nanoplatform for breast cancer therapy

Biomaterials ◽  
2015 ◽  
Vol 59 ◽  
pp. 88-101 ◽  
Author(s):  
Arpan Satsangi ◽  
Sudipa S. Roy ◽  
Rajiv K. Satsangi ◽  
Anthony W. Tolcher ◽  
Ratna K. Vadlamudi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Breast Cancer Therapy ◽  
Targeted Drug

scholarly journals Single-step surface functionalization of polymeric nanoparticles for targeted drug delivery

Biomaterials ◽  
2009 ◽  
Vol 30 (5) ◽  
pp. 859-866 ◽  
Author(s):  
Yogesh B. Patil ◽  
Udaya S. Toti ◽  
Ayman Khdair ◽  
Linan Ma ◽  
Jayanth Panyam
Keyword(s):  
Drug Delivery ◽  
Surface Functionalization ◽  
Targeted Drug Delivery ◽  
Polymeric Nanoparticles ◽  
Single Step ◽  
Targeted Drug

scholarly journals Traditional, unfairly forgotten, rarely used and promising drug delivery methods in ophthalmology: a clinical interpretation (part 1)

2019 ◽  
Vol 12 (2) ◽  
pp. 83-95 ◽  
Author(s):  
A. V. Kuroyedov ◽  
V. V. Brzhesky ◽  
E. A. Krinitsyna
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Drug Concentration ◽  
Targeted Drug Delivery ◽  
Anatomical Structure ◽  
Delivery Methods ◽  
Clinical Interpretation ◽  
Physiological Properties ◽  
Challenging Tasks ◽  
Targeted Drug

Ocular targeted drug delivery is one of the most challenging tasks for pharmaceutical researchers and practical ophthalmologists. The possibilities of drug delivery to the eye are naturally determined by the anatomical structure of the eye and its physiological properties, which restrict the period when therapeutically required drug concentration could be maintained. Combined drug delivery schemes may, potentially, improve the patient’s acceptance of treatment, reduce side effects, increase efficacy, and eventually preserve vision.

Approaches for Targeted Drug Delivery to Colon

2010 ◽  
Vol 3 (1) ◽  
Author(s):  
Shyam Prasad ◽  
Vidhu Aeri ◽  
Yashwant .
Keyword(s):  
Drug Delivery ◽  
Drug Interaction ◽  
Gastrointestinal Tract ◽  
Side Effects ◽  
Drug Delivery System ◽  
Targeted Drug Delivery ◽  
Biological Membrane ◽  
Colonic Disease ◽  
Conventional Drug ◽  
Targeted Drug

The conventional drug delivery system for colonic disease may leads to absorption of drug across biological membrane of gastrointestinal tract (GIT). The absorption of drug throughout GIT may leads to increase in dose and associated side effects. Colon targeted drug delivery (CTDD) is a method of delivering medication to a patient in a manner that increases concentration of the medication in colon relative to other part of GIT. The aim of CTDD is to prolong, localize, target and have protected drug interaction to diseased tissue. The present review deals with primary as well as recent approaches of delivery of drug to colon.

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