Stimuli-responsive carbon nanotubes for targeted drug delivery

Author(s):  
M. Saquib Hasnain ◽  
Syed Anees Ahmad ◽  
Mohammad Niyaz Hoda ◽  
Sanjay Rishishwar ◽  
Poonam Rishishwar ◽  
...  
2010 ◽  
Vol 122 (26) ◽  
pp. 4507-4510 ◽  
Author(s):  
Eunju Kim ◽  
Dongwoo Kim ◽  
Hyuntae Jung ◽  
Jiyeong Lee ◽  
Somak Paul ◽  
...  

2016 ◽  
Vol 1 (6) ◽  
pp. 480-487 ◽  
Author(s):  
Ye Tian ◽  
Ranran Guo ◽  
Yunfeng Jiao ◽  
Yangfei Sun ◽  
Shun Shen ◽  
...  

Transferrin-capped hollow mesoporous silica nanoparticles through disulfide linkages realize tumor-targeting delivery and glutathione-induced drug release.


2017 ◽  
Vol 9 (14) ◽  
pp. 12227-12240 ◽  
Author(s):  
Yu Zhang ◽  
Qin Guo ◽  
Sai An ◽  
Yifei Lu ◽  
Jianfeng Li ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6707
Author(s):  
Mohamed Rahamathulla ◽  
Rohit R. Bhosale ◽  
Riyaz A. M. Osmani ◽  
Kasturi C. Mahima ◽  
Asha P. Johnson ◽  
...  

Current discoveries as well as research findings on various types of carbon nanostructures have inspired research into their utilization in a number of fields. These carbon nanostructures offer uses in pharmacy, medicine and different therapies. One such unique carbon nanostructure includes carbon nanotubes (CNTs), which are one-dimensional allotropes of carbon nanostructure that can have a length-to-diameter ratio greater than 1,000,000. After their discovery, CNTs have drawn extensive research attention due to their excellent material properties. Their physical, chemical and electronic properties are excellent and their composites provide great possibilities for enormous nanometer applications. The current study provides a systematic review based on prior literature review and data gathered from various sources. The various research studies from many research labs and organizations were systematically retrieved, collected, compiled and written. The entire collection and compilation of this review concluded the use of CNT approaches and their efficacy and safety for the treatment of various diseases such as brain tumors or cancer via nanotechnology-based drug delivery, phototherapy, gene therapy, antiviral therapy, antifungal therapy, antibacterial therapy and other biomedical applications. The current review covers diverse applications of CNTs in designing a range of targeted drug delivery systems and application for various therapies. It concludes with a discussion on how CNTs based medicines can expand in the future.


2020 ◽  
Vol 2 (2) ◽  
pp. 35-50
Author(s):  
Pramod Vishwanath Prasad ◽  
Kakali Purkayastha ◽  
Utkarsh Sharma ◽  
Mayadhar Barik

Emergence of various nanoscale drug carrier platforms as Drug Delivery Systems (DDS) has revolutionized the field of medicine.Nonetheless, theside-effects due to non-specific distribution of anticancer therapeutics in normal, healthy tissues remain to be a prime pitfall in curing cancers. Therefore, to achieve a better therapeutic efficacy, the use of a target-specific delivery, combined with a stimuli-responsive nanocarrier system, particularly pH-sensitive nanosystems offer an attractive strategy. Targeted drug delivery through pH-sensitive nanosystems offer the potential to enhance the therapeutic index of anticancer agents, either by increasing the drug concentration in tumor cells and/or by decreasing the exposure in normal host tissues. Therefore, nanoscale-based drug delivery through pH-sensitive nanosystems seem to be a boon for treating gynaecological cancers (as well as other cancers) without side-effects or with least harm to normal healthy tissues.


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