A Survey of Machine Learning and Deep Learning Applications in Genome Editing

2021 ◽  
pp. 145-162
Author(s):  
Talal Almutiri ◽  
Faisal Saeed ◽  
Manar Alassaf
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Genome Editing

scholarly journals CRISPRpred(SEQ): a sequence based tool for sgRNA on target activity prediction [(almost) beating Deep Learning pipelines by traditional machine learning]

2019 ◽  
Author(s):  
Ali Haisam Muhammad Rafid ◽  
Md. Toufikuzzaman ◽  
Mohammad Saifur Rahman ◽  
M. Sohel Rahman
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Genome Editing ◽  
Cell Lines ◽  
Genetic Diseases ◽  
Machine Learning Techniques ◽  
Activity Prediction ◽  
Current State ◽  
Learning Techniques ◽  
Target Activity

AbstractAn accurate and fast genome editing tool can be used to treat genetic diseases, modify crops genetically etc. However, a tool that has low accuracy can be risky to use, as incorrect genome editing may have severe consequences. Although many tools have been developed in the past, there are still room for further improvement. In this paper, we present CRISPRpred(SEQ), a sequence based tool for sgRNA on target activity prediction that leverages only traditional machine learning techniques. We compare the results of CRISPRpred(SEQ) with that of DeepCRISPR, the current state-of-the-art, which uses a deep learning pipeline. In spite of using only traditional machine learning methods, we are able to beat DeepCRISPR for the three out of four cell lines in the benchmark dataset convincingly (2.174%, 6.905% and 8.119% improvement for the three cell lines), which is quite outstanding.

Deep Learning Based High-Resolution Remote Sensing Image classification

2017 ◽  
Vol 7 (10) ◽  
pp. 22
Author(s):  
Sumit Kaur
Keyword(s):  
Machine Learning ◽  
Remote Sensing ◽  
Deep Learning ◽  
Image Classification ◽  
Language Processing ◽  
Object Perception ◽  
Remote Sensing Image ◽  
Research Area ◽  
Remote Sensing Image Classification ◽  
Unsupervised Algorithms

Abstract- Deep learning is an emerging research area in machine learning and pattern recognition field which has been presented with the goal of drawing Machine Learning nearer to one of its unique objectives, Artificial Intelligence. It tries to mimic the human brain, which is capable of processing and learning from the complex input data and solving different kinds of complicated tasks well. Deep learning (DL) basically based on a set of supervised and unsupervised algorithms that attempt to model higher level abstractions in data and make it self-learning for hierarchical representation for classification. In the recent years, it has attracted much attention due to its state-of-the-art performance in diverse areas like object perception, speech recognition, computer vision, collaborative filtering and natural language processing. This paper will present a survey on different deep learning techniques for remote sensing image classification. 

Data science in economics: comprehensive review of advanced machine learning and deep learning methods

2020 ◽  
Author(s):  
Saeed Nosratabadi ◽  
Amir Mosavi ◽  
Puhong Duan ◽  
Pedram Ghamisi ◽  
Ferdinand Filip ◽  
...  
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Data Science ◽  
State Of The Art ◽  
Science Methods ◽  
Learning Models ◽  
Diverse Range ◽  
Hybrid Machine ◽  
Economics Research

This paper provides a state-of-the-art investigation of advances in data science in emerging economic applications. The analysis was performed on novel data science methods in four individual classes of deep learning models, hybrid deep learning models, hybrid machine learning, and ensemble models. Application domains include a wide and diverse range of economics research from the stock market, marketing, and e-commerce to corporate banking and cryptocurrency. Prisma method, a systematic literature review methodology, was used to ensure the quality of the survey. The findings reveal that the trends follow the advancement of hybrid models, which, based on the accuracy metric, outperform other learning algorithms. It is further expected that the trends will converge toward the advancements of sophisticated hybrid deep learning models.

Deep Learning for text in limted data settings

2020 ◽  
Author(s):  
Pathikkumar Patel ◽  
Bhargav Lad ◽  
Jinan Fiaidhi
Keyword(s):  
Machine Learning ◽  
Time Series ◽  
Deep Learning ◽  
Sentiment Analysis ◽  
Transfer Learning ◽  
Text Classification ◽  
State Of The Art ◽  
Time Series Forecasting ◽  
Text Data ◽  
Performance Levels

During the last few years, RNN models have been extensively used and they have proven to be better for sequence and text data. RNNs have achieved state-of-the-art performance levels in several applications such as text classification, sequence to sequence modelling and time series forecasting. In this article we will review different Machine Learning and Deep Learning based approaches for text data and look at the results obtained from these methods. This work also explores the use of transfer learning in NLP and how it affects the performance of models on a specific application of sentiment analysis.

Data Science in Economics: Comprehensive Review of Advanced Machine Learning and Deep Learning Methods

2020 ◽  
Author(s):  
Saeed Nosratabadi ◽  
Amir Mosavi ◽  
Puhong Duan ◽  
Pedram Ghamisi ◽  
Filip Ferdinand ◽  
...  
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Data Science ◽  
Learning Methods ◽  
Comprehensive Review

Virtual Screening Meets Deep Learning

2018 ◽  
Vol 15 (1) ◽  
pp. 6-28 ◽  
Author(s):  
Javier Pérez-Sianes ◽  
Horacio Pérez-Sánchez ◽  
Fernando Díaz
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Virtual Screening ◽  
Great Increase ◽  
New Drugs ◽  
Learning Approach ◽  
Screening Strategies ◽  
Computer Aided ◽  
Recent Developments

Background: Automated compound testing is currently the de facto standard method for drug screening, but it has not brought the great increase in the number of new drugs that was expected. Computer- aided compounds search, known as Virtual Screening, has shown the benefits to this field as a complement or even alternative to the robotic drug discovery. There are different methods and approaches to address this problem and most of them are often included in one of the main screening strategies. Machine learning, however, has established itself as a virtual screening methodology in its own right and it may grow in popularity with the new trends on artificial intelligence. Objective: This paper will attempt to provide a comprehensive and structured review that collects the most important proposals made so far in this area of research. Particular attention is given to some recent developments carried out in the machine learning field: the deep learning approach, which is pointed out as a future key player in the virtual screening landscape.

Deep Learning in Disease Diagnosis: Models and Datasets

2020 ◽  
Vol 15 ◽  
Author(s):  
Deeksha Saxena ◽  
Mohammed Haris Siddiqui ◽  
Rajnish Kumar
Keyword(s):  
Biological Sciences ◽  
Machine Learning ◽  
Deep Learning ◽  
Disease Diagnosis ◽  
Learning Models ◽  
Data Types ◽  
Related Data ◽  
Abstract Level ◽  
Experimental Validations ◽  
Selection Of

Background: Deep learning (DL) is an Artificial neural network-driven framework with multiple levels of representation for which non-linear modules combined in such a way that the levels of representation can be enhanced from lower to a much abstract level. Though DL is used widely in almost every field, it has largely brought a breakthrough in biological sciences as it is used in disease diagnosis and clinical trials. DL can be clubbed with machine learning, but at times both are used individually as well. DL seems to be a better platform than machine learning as the former does not require an intermediate feature extraction and works well with larger datasets. DL is one of the most discussed fields among the scientists and researchers these days for diagnosing and solving various biological problems. However, deep learning models need some improvisation and experimental validations to be more productive. Objective: To review the available DL models and datasets that are used in disease diagnosis. Methods: Available DL models and their applications in disease diagnosis were reviewed discussed and tabulated. Types of datasets and some of the popular disease related data sources for DL were highlighted. Results: We have analyzed the frequently used DL methods, data types and discussed some of the recent deep learning models used for solving different biological problems. Conclusion: The review presents useful insights about DL methods, data types, selection of DL models for the disease diagnosis.

Android Malware Detection Techniques: A Literature Review

2020 ◽  
Vol 14 ◽  
Author(s):  
Meghna Dhalaria ◽  
Ekta Gandotra
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Malware Detection ◽  
Future Research ◽  
Android Malware ◽  
Detection Techniques ◽  
Android Malware Detection ◽  
Future Research Directions ◽  
To Come ◽  
Tools And Techniques

Purpose: This paper provides the basics of Android malware, its evolution and tools and techniques for malware analysis. Its main aim is to present a review of the literature on Android malware detection using machine learning and deep learning and identify the research gaps. It provides the insights obtained through literature and future research directions which could help researchers to come up with robust and accurate techniques for classification of Android malware. Design/Methodology/Approach: This paper provides a review of the basics of Android malware, its evolution timeline and detection techniques. It includes the tools and techniques for analyzing the Android malware statically and dynamically for extracting features and finally classifying these using machine learning and deep learning algorithms. Findings: The number of Android users is expanding very fast due to the popularity of Android devices. As a result, there are more risks to Android users due to the exponential growth of Android malware. On-going research aims to overcome the constraints of earlier approaches for malware detection. As the evolving malware are complex and sophisticated, earlier approaches like signature based and machine learning based are not able to identify these timely and accurately. The findings from the review shows various limitations of earlier techniques i.e. requires more detection time, high false positive and false negative rate, low accuracy in detecting sophisticated malware and less flexible. Originality/value: This paper provides a systematic and comprehensive review on the tools and techniques being employed for analysis, classification and identification of Android malicious applications. It includes the timeline of Android malware evolution, tools and techniques for analyzing these statically and dynamically for the purpose of extracting features and finally using these features for their detection and classification using machine learning and deep learning algorithms. On the basis of the detailed literature review, various research gaps are listed. The paper also provides future research directions and insights which could help researchers to come up with innovative and robust techniques for detecting and classifying the Android malware.

Sign in / Sign up

Export Citation Format

Share Document